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A cell line-derived, immune-competent neurospheroid model to study neuroinflammation and human brain disorders.

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Title: A cell line-derived, immune-competent neurospheroid model to study neuroinflammation and human brain disorders.
Authors: Bufi AA; Department of Life Science and Public Health, Università Cattolica del Sacro Cuore, Rome, Italy.; Laboratory of Experimental Hematology, Vaccine and Infectious Disease Institute (Vaxinfectio), University of Antwerp, Antwerp, Belgium., Papait A; Department of Life Science and Public Health, Università Cattolica del Sacro Cuore, Rome, Italy.; Fondazione Policlinico Universitario 'Agostino Gemelli', Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS), Rome, Italy., Farigu S; Centro di Ricerca E. Menni, Fondazione Poliambulanza Istituto Ospedaliero, Brescia, Italy., Vertua E; Centro di Ricerca E. Menni, Fondazione Poliambulanza Istituto Ospedaliero, Brescia, Italy., Bonassi Signoroni P; Centro di Ricerca E. Menni, Fondazione Poliambulanza Istituto Ospedaliero, Brescia, Italy., Scalvini E; Centro di Ricerca E. Menni, Fondazione Poliambulanza Istituto Ospedaliero, Brescia, Italy., Giuzzi E; Centro di Ricerca E. Menni, Fondazione Poliambulanza Istituto Ospedaliero, Brescia, Italy., Paini A; Centro di Ricerca E. Menni, Fondazione Poliambulanza Istituto Ospedaliero, Brescia, Italy., Chiodelli P; Department of Life Science and Public Health, Università Cattolica del Sacro Cuore, Rome, Italy.; Fondazione Policlinico Universitario 'Agostino Gemelli', Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS), Rome, Italy., Silini AR; Centro di Ricerca E. Menni, Fondazione Poliambulanza Istituto Ospedaliero, Brescia, Italy., Ponsaerts P; Laboratory of Experimental Hematology, Vaccine and Infectious Disease Institute (Vaxinfectio), University of Antwerp, Antwerp, Belgium., Parolini O; Department of Life Science and Public Health, Università Cattolica del Sacro Cuore, Rome, Italy.; Fondazione IRCCS Casa Sollievo della Sofferenza, San Giovanni Rotondo, Foggia, Italy.
Source: Frontiers in immunology [Front Immunol] 2026 Mar 17; Vol. 17, pp. 1792896. Date of Electronic Publication: 2026 Mar 17 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: A cell line-derived, immune-competent neurospheroid model to study neuroinflammation and human brain disorders.
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  Data: <searchLink fieldCode="AU" term="%22Bufi+AA%22">Bufi AA</searchLink>; Department of Life Science and Public Health, Università Cattolica del Sacro Cuore, Rome, Italy.; Laboratory of Experimental Hematology, Vaccine and Infectious Disease Institute (Vaxinfectio), University of Antwerp, Antwerp, Belgium.<br /><searchLink fieldCode="AU" term="%22Papait+A%22">Papait A</searchLink>; Department of Life Science and Public Health, Università Cattolica del Sacro Cuore, Rome, Italy.; Fondazione Policlinico Universitario 'Agostino Gemelli', Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS), Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Farigu+S%22">Farigu S</searchLink>; Centro di Ricerca E. Menni, Fondazione Poliambulanza Istituto Ospedaliero, Brescia, Italy.<br /><searchLink fieldCode="AU" term="%22Vertua+E%22">Vertua E</searchLink>; Centro di Ricerca E. Menni, Fondazione Poliambulanza Istituto Ospedaliero, Brescia, Italy.<br /><searchLink fieldCode="AU" term="%22Bonassi+Signoroni+P%22">Bonassi Signoroni P</searchLink>; Centro di Ricerca E. Menni, Fondazione Poliambulanza Istituto Ospedaliero, Brescia, Italy.<br /><searchLink fieldCode="AU" term="%22Scalvini+E%22">Scalvini E</searchLink>; Centro di Ricerca E. Menni, Fondazione Poliambulanza Istituto Ospedaliero, Brescia, Italy.<br /><searchLink fieldCode="AU" term="%22Giuzzi+E%22">Giuzzi E</searchLink>; Centro di Ricerca E. Menni, Fondazione Poliambulanza Istituto Ospedaliero, Brescia, Italy.<br /><searchLink fieldCode="AU" term="%22Paini+A%22">Paini A</searchLink>; Centro di Ricerca E. Menni, Fondazione Poliambulanza Istituto Ospedaliero, Brescia, Italy.<br /><searchLink fieldCode="AU" term="%22Chiodelli+P%22">Chiodelli P</searchLink>; Department of Life Science and Public Health, Università Cattolica del Sacro Cuore, Rome, Italy.; Fondazione Policlinico Universitario 'Agostino Gemelli', Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS), Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Silini+AR%22">Silini AR</searchLink>; Centro di Ricerca E. Menni, Fondazione Poliambulanza Istituto Ospedaliero, Brescia, Italy.<br /><searchLink fieldCode="AU" term="%22Ponsaerts+P%22">Ponsaerts P</searchLink>; Laboratory of Experimental Hematology, Vaccine and Infectious Disease Institute (Vaxinfectio), University of Antwerp, Antwerp, Belgium.<br /><searchLink fieldCode="AU" term="%22Parolini+O%22">Parolini O</searchLink>; Department of Life Science and Public Health, Università Cattolica del Sacro Cuore, Rome, Italy.; Fondazione IRCCS Casa Sollievo della Sofferenza, San Giovanni Rotondo, Foggia, Italy.
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