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Real-world effectiveness of denosumab compared to teriparatide in patients with severe osteoporosis.

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Title: Real-world effectiveness of denosumab compared to teriparatide in patients with severe osteoporosis.
Authors: Birtolo MF; Department of Biomedical Sciences, Humanitas University, Milan, Italy.; Endocrinology, Diabetology, Medical Andrology Unit, IRCCS Humanitas Research Hospital, Milan, Italy., Piasentier A; Department of Biomedical Sciences, Humanitas University, Milan, Italy.; Endocrinology, Diabetology, Medical Andrology Unit, IRCCS Humanitas Research Hospital, Milan, Italy., Dutu AD; Department of Biomedical Sciences, Humanitas University, Milan, Italy.; Radiotherapy and Radiosurgery Department, IRCCS Humanitas Research Hospital, Rozzano, Milan, Italy., Vena W; Department of Biomedical Sciences, Humanitas University, Milan, Italy.; Endocrinology and Diabetology Unit, Humanitas Gavazzeni, Bergamo, Italy., Morenghi E; Department of Biomedical Sciences, Humanitas University, Milan, Italy.; Biostatistics Unit, IRCCS Humanitas Research Hospital, Milan, Italy., Pigni S; Department of Biomedical Sciences, Humanitas University, Milan, Italy.; Endocrinology, Diabetology, Medical Andrology Unit, IRCCS Humanitas Research Hospital, Milan, Italy., Gentile LMS; Department of Biomedical Sciences, Humanitas University, Milan, Italy.; Endocrinology, Diabetology, Medical Andrology Unit, IRCCS Humanitas Research Hospital, Milan, Italy., Fanti A; Department of Biomedical Sciences, Humanitas University, Milan, Italy.; Endocrinology, Diabetology, Medical Andrology Unit, IRCCS Humanitas Research Hospital, Milan, Italy., Vitale V; Department of Biomedical Sciences, Humanitas University, Milan, Italy.; Endocrinology, Diabetology, Medical Andrology Unit, IRCCS Humanitas Research Hospital, Milan, Italy., Pucci A; Department of Biomedical Sciences, Humanitas University, Milan, Italy.; Endocrinology, Diabetology, Medical Andrology Unit, IRCCS Humanitas Research Hospital, Milan, Italy., Capo G; Neurosurgery Department, IRCCS Humanitas Research Hospital, Milan, Italy., Tomei M; Neurosurgery Department, IRCCS Humanitas Research Hospital, Milan, Italy., Brembilla C; Neurosurgery Department, IRCCS Humanitas Research Hospital, Milan, Italy., Fornari M; Neurosurgery Department, IRCCS Humanitas Research Hospital, Milan, Italy., Laghi A; Department of Biomedical Sciences, Humanitas University, Milan, Italy.; Radiology Department, IRCCS Humanitas Research Hospital, Milan, Italy., Politi LS; Department of Biomedical Sciences, Humanitas University, Milan, Italy.; Radiology Department, IRCCS Humanitas Research Hospital, Milan, Italy., Bossi AC; Endocrinology and Diabetology Unit, Humanitas Gavazzeni, Bergamo, Italy., Lania AGA; Department of Biomedical Sciences, Humanitas University, Milan, Italy.; Endocrinology, Diabetology, Medical Andrology Unit, IRCCS Humanitas Research Hospital, Milan, Italy., Mazziotti G; Department of Biomedical Sciences, Humanitas University, Milan, Italy.; Endocrinology, Diabetology, Medical Andrology Unit, IRCCS Humanitas Research Hospital, Milan, Italy.
Source: Frontiers in endocrinology [Front Endocrinol (Lausanne)] 2026 Mar 17; Vol. 17, pp. 1744054. Date of Electronic Publication: 2026 Mar 17 (Print Publication: 2026).
Publication Type: Journal Article; Comparative Study
Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101555782 Publication Model: eCollection Cited Medium: Print ISSN: 1664-2392 (Print) Linking ISSN: 16642392 NLM ISO Abbreviation: Front Endocrinol (Lausanne) Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Real-world effectiveness of denosumab compared to teriparatide in patients with severe osteoporosis.
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  Data: <searchLink fieldCode="AU" term="%22Birtolo+MF%22">Birtolo MF</searchLink>; Department of Biomedical Sciences, Humanitas University, Milan, Italy.; Endocrinology, Diabetology, Medical Andrology Unit, IRCCS Humanitas Research Hospital, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Piasentier+A%22">Piasentier A</searchLink>; Department of Biomedical Sciences, Humanitas University, Milan, Italy.; Endocrinology, Diabetology, Medical Andrology Unit, IRCCS Humanitas Research Hospital, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Dutu+AD%22">Dutu AD</searchLink>; Department of Biomedical Sciences, Humanitas University, Milan, Italy.; Radiotherapy and Radiosurgery Department, IRCCS Humanitas Research Hospital, Rozzano, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Vena+W%22">Vena W</searchLink>; Department of Biomedical Sciences, Humanitas University, Milan, Italy.; Endocrinology and Diabetology Unit, Humanitas Gavazzeni, Bergamo, Italy.<br /><searchLink fieldCode="AU" term="%22Morenghi+E%22">Morenghi E</searchLink>; Department of Biomedical Sciences, Humanitas University, Milan, Italy.; Biostatistics Unit, IRCCS Humanitas Research Hospital, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Pigni+S%22">Pigni S</searchLink>; Department of Biomedical Sciences, Humanitas University, Milan, Italy.; Endocrinology, Diabetology, Medical Andrology Unit, IRCCS Humanitas Research Hospital, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Gentile+LMS%22">Gentile LMS</searchLink>; Department of Biomedical Sciences, Humanitas University, Milan, Italy.; Endocrinology, Diabetology, Medical Andrology Unit, IRCCS Humanitas Research Hospital, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Fanti+A%22">Fanti A</searchLink>; Department of Biomedical Sciences, Humanitas University, Milan, Italy.; Endocrinology, Diabetology, Medical Andrology Unit, IRCCS Humanitas Research Hospital, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Vitale+V%22">Vitale V</searchLink>; Department of Biomedical Sciences, Humanitas University, Milan, Italy.; Endocrinology, Diabetology, Medical Andrology Unit, IRCCS Humanitas Research Hospital, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Pucci+A%22">Pucci A</searchLink>; Department of Biomedical Sciences, Humanitas University, Milan, Italy.; Endocrinology, Diabetology, Medical Andrology Unit, IRCCS Humanitas Research Hospital, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Capo+G%22">Capo G</searchLink>; Neurosurgery Department, IRCCS Humanitas Research Hospital, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Tomei+M%22">Tomei M</searchLink>; Neurosurgery Department, IRCCS Humanitas Research Hospital, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Brembilla+C%22">Brembilla C</searchLink>; Neurosurgery Department, IRCCS Humanitas Research Hospital, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Fornari+M%22">Fornari M</searchLink>; Neurosurgery Department, IRCCS Humanitas Research Hospital, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Laghi+A%22">Laghi A</searchLink>; Department of Biomedical Sciences, Humanitas University, Milan, Italy.; Radiology Department, IRCCS Humanitas Research Hospital, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Politi+LS%22">Politi LS</searchLink>; Department of Biomedical Sciences, Humanitas University, Milan, Italy.; Radiology Department, IRCCS Humanitas Research Hospital, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Bossi+AC%22">Bossi AC</searchLink>; Endocrinology and Diabetology Unit, Humanitas Gavazzeni, Bergamo, Italy.<br /><searchLink fieldCode="AU" term="%22Lania+AGA%22">Lania AGA</searchLink>; Department of Biomedical Sciences, Humanitas University, Milan, Italy.; Endocrinology, Diabetology, Medical Andrology Unit, IRCCS Humanitas Research Hospital, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Mazziotti+G%22">Mazziotti G</searchLink>; Department of Biomedical Sciences, Humanitas University, Milan, Italy.; Endocrinology, Diabetology, Medical Andrology Unit, IRCCS Humanitas Research Hospital, Milan, Italy.
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