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Vaginal microbial community state types fail to predict IVF outcomes, whereas Ureaplasma parvum and Lactobacillus iners are negative predictors of implantation, clinical pregnancy, and live birth.

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Title: Vaginal microbial community state types fail to predict IVF outcomes, whereas Ureaplasma parvum and Lactobacillus iners are negative predictors of implantation, clinical pregnancy, and live birth.
Authors: Graspeuntner S; Institute of Medical Microbiology, University of Lübeck, Lübeck, Germany.; German Centre for Infection Research, Partner Site Hamburg-Lübeck-Borstel-Riems, Lübeck, Germany.; Medical Clinic III, University Hospital Schleswig-Holstein, Lübeck, Germany., Lupatsii M; Institute of Medical Microbiology, University of Lübeck, Lübeck, Germany., Hamala N; Department of Gynaecological Endocrinology and Reproductive Medicine, University Hospital of Schleswig-Holstein, Campus Lübeck and Universitäres Kinderwunschzentrum Lübeck und Manhagen, Lübeck, Germany., Masuch A; Department of Gynaecological Endocrinology and Reproductive Medicine, University Hospital of Schleswig-Holstein, Campus Lübeck and Universitäres Kinderwunschzentrum Lübeck und Manhagen, Lübeck, Germany., Depenbusch M; Department of Gynaecological Endocrinology and Reproductive Medicine, University Hospital of Schleswig-Holstein, Campus Lübeck and Universitäres Kinderwunschzentrum Lübeck und Manhagen, Lübeck, Germany., Pfeffer I; Institute of Medical Microbiology, University of Lübeck, Lübeck, Germany., Schultze-Mosgau A; Department of Gynaecological Endocrinology and Reproductive Medicine, University Hospital of Schleswig-Holstein, Campus Lübeck and Universitäres Kinderwunschzentrum Lübeck und Manhagen, Lübeck, Germany., Eggersmann TK; Department of Gynaecological Endocrinology and Reproductive Medicine, University Hospital of Schleswig-Holstein, Campus Lübeck and Universitäres Kinderwunschzentrum Lübeck und Manhagen, Lübeck, Germany., Rupp J; Institute of Medical Microbiology, University of Lübeck, Lübeck, Germany.; German Centre for Infection Research, Partner Site Hamburg-Lübeck-Borstel-Riems, Lübeck, Germany.; Infectious Disease Clinic, University Hospital Schleswig-Holstein, Lübeck, Germany., Griesinger G; Department of Gynaecological Endocrinology and Reproductive Medicine, University Hospital of Schleswig-Holstein, Campus Lübeck and Universitäres Kinderwunschzentrum Lübeck und Manhagen, Lübeck, Germany.
Source: Human reproduction open [Hum Reprod Open] 2026 Mar 05; Vol. 2026 (2), pp. hoag018. Date of Electronic Publication: 2026 Mar 05 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 101722764 Publication Model: eCollection Cited Medium: Internet ISSN: 2399-3529 (Electronic) Linking ISSN: 23993529 NLM ISO Abbreviation: Hum Reprod Open Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Vaginal microbial community state types fail to predict IVF outcomes, whereas Ureaplasma parvum and Lactobacillus iners are negative predictors of implantation, clinical pregnancy, and live birth.
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  Data: <searchLink fieldCode="AU" term="%22Graspeuntner+S%22">Graspeuntner S</searchLink>; Institute of Medical Microbiology, University of Lübeck, Lübeck, Germany.; German Centre for Infection Research, Partner Site Hamburg-Lübeck-Borstel-Riems, Lübeck, Germany.; Medical Clinic III, University Hospital Schleswig-Holstein, Lübeck, Germany.<br /><searchLink fieldCode="AU" term="%22Lupatsii+M%22">Lupatsii M</searchLink>; Institute of Medical Microbiology, University of Lübeck, Lübeck, Germany.<br /><searchLink fieldCode="AU" term="%22Hamala+N%22">Hamala N</searchLink>; Department of Gynaecological Endocrinology and Reproductive Medicine, University Hospital of Schleswig-Holstein, Campus Lübeck and Universitäres Kinderwunschzentrum Lübeck und Manhagen, Lübeck, Germany.<br /><searchLink fieldCode="AU" term="%22Masuch+A%22">Masuch A</searchLink>; Department of Gynaecological Endocrinology and Reproductive Medicine, University Hospital of Schleswig-Holstein, Campus Lübeck and Universitäres Kinderwunschzentrum Lübeck und Manhagen, Lübeck, Germany.<br /><searchLink fieldCode="AU" term="%22Depenbusch+M%22">Depenbusch M</searchLink>; Department of Gynaecological Endocrinology and Reproductive Medicine, University Hospital of Schleswig-Holstein, Campus Lübeck and Universitäres Kinderwunschzentrum Lübeck und Manhagen, Lübeck, Germany.<br /><searchLink fieldCode="AU" term="%22Pfeffer+I%22">Pfeffer I</searchLink>; Institute of Medical Microbiology, University of Lübeck, Lübeck, Germany.<br /><searchLink fieldCode="AU" term="%22Schultze-Mosgau+A%22">Schultze-Mosgau A</searchLink>; Department of Gynaecological Endocrinology and Reproductive Medicine, University Hospital of Schleswig-Holstein, Campus Lübeck and Universitäres Kinderwunschzentrum Lübeck und Manhagen, Lübeck, Germany.<br /><searchLink fieldCode="AU" term="%22Eggersmann+TK%22">Eggersmann TK</searchLink>; Department of Gynaecological Endocrinology and Reproductive Medicine, University Hospital of Schleswig-Holstein, Campus Lübeck and Universitäres Kinderwunschzentrum Lübeck und Manhagen, Lübeck, Germany.<br /><searchLink fieldCode="AU" term="%22Rupp+J%22">Rupp J</searchLink>; Institute of Medical Microbiology, University of Lübeck, Lübeck, Germany.; German Centre for Infection Research, Partner Site Hamburg-Lübeck-Borstel-Riems, Lübeck, Germany.; Infectious Disease Clinic, University Hospital Schleswig-Holstein, Lübeck, Germany.<br /><searchLink fieldCode="AU" term="%22Griesinger+G%22">Griesinger G</searchLink>; Department of Gynaecological Endocrinology and Reproductive Medicine, University Hospital of Schleswig-Holstein, Campus Lübeck and Universitäres Kinderwunschzentrum Lübeck und Manhagen, Lübeck, Germany.
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              Text: 2026 Mar 05
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