Saikosaponin-d attenuates postpartum estrogen withdrawal-induced depressive symptoms by modulating glucocorticoid metabolism and inhibiting hippocampal NLRP3 inflammatory vesicle activation.
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| Title: | Saikosaponin-d attenuates postpartum estrogen withdrawal-induced depressive symptoms by modulating glucocorticoid metabolism and inhibiting hippocampal NLRP3 inflammatory vesicle activation. |
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| Authors: | Zhai X; Department of Pharmacy, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Jiefang Avenue, Wuhan, 430022, People's Republic Of China. zhaixuejia@hust.edu.cn., Yang Q; School of Pharmacy, Hubei University of Chinese Medicine, 430065, Wuhan, People's Republic Of China., Zhao Y; Department of Pediatrics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, People's Republic Of China., Zeng X; School of Pharmacy, Hubei University of Chinese Medicine, 430065, Wuhan, People's Republic Of China., He Y; Department of Pharmacy, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Jiefang Avenue, Wuhan, 430022, People's Republic Of China., You Q; Engineering Research Center of TCM Protection Technology and New Product Development for the Elderly Brain Health, Ministry of Education, Hubei University of Chinese Medicine, Wuhan, 430065, People's Republic Of China.; Hubei Shizhen Laboratory, 430065, Wuhan , People's Republic Of China. |
| Source: | Metabolic brain disease [Metab Brain Dis] 2026 Apr 02; Vol. 41 (1). Date of Electronic Publication: 2026 Apr 02. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Springer Country of Publication: United States NLM ID: 8610370 Publication Model: Electronic Cited Medium: Internet ISSN: 1573-7365 (Electronic) Linking ISSN: 08857490 NLM ISO Abbreviation: Metab Brain Dis Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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