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Protectin DX reduces inflammatory pain initiated by superoxide anion in mice: targeting leukocyte recruitment, oxidative stress, cytokine production and TRPV1+ nociceptive sensory neuron activation.

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Title: Protectin DX reduces inflammatory pain initiated by superoxide anion in mice: targeting leukocyte recruitment, oxidative stress, cytokine production and TRPV1+ nociceptive sensory neuron activation.
Authors: Carneiro JA; Department of Immunology, Parasitology and General Pathology, Londrina State University, Rodovia Celso Garcia Cid, Km 380, PR 445, Caixa Postal 10.011, Londrina, Paraná, 86057-970, Brazil., Bianchini BHS; Department of Immunology, Parasitology and General Pathology, Londrina State University, Rodovia Celso Garcia Cid, Km 380, PR 445, Caixa Postal 10.011, Londrina, Paraná, 86057-970, Brazil., Martelossi-Cebinelli G; Department of Immunology, Parasitology and General Pathology, Londrina State University, Rodovia Celso Garcia Cid, Km 380, PR 445, Caixa Postal 10.011, Londrina, Paraná, 86057-970, Brazil., Artero NA; Department of Immunology, Parasitology and General Pathology, Londrina State University, Rodovia Celso Garcia Cid, Km 380, PR 445, Caixa Postal 10.011, Londrina, Paraná, 86057-970, Brazil., Maximiano TKE; Department of Immunology, Parasitology and General Pathology, Londrina State University, Rodovia Celso Garcia Cid, Km 380, PR 445, Caixa Postal 10.011, Londrina, Paraná, 86057-970, Brazil., Franciosi A; Department of Immunology, Parasitology and General Pathology, Londrina State University, Rodovia Celso Garcia Cid, Km 380, PR 445, Caixa Postal 10.011, Londrina, Paraná, 86057-970, Brazil., Dionisio AM; Department of Immunology, Parasitology and General Pathology, Londrina State University, Rodovia Celso Garcia Cid, Km 380, PR 445, Caixa Postal 10.011, Londrina, Paraná, 86057-970, Brazil., Yaekashi KM; Department of Immunology, Parasitology and General Pathology, Londrina State University, Rodovia Celso Garcia Cid, Km 380, PR 445, Caixa Postal 10.011, Londrina, Paraná, 86057-970, Brazil., Carvalho TT; Department of Immunology, Parasitology and General Pathology, Londrina State University, Rodovia Celso Garcia Cid, Km 380, PR 445, Caixa Postal 10.011, Londrina, Paraná, 86057-970, Brazil.; Department of Biomedical Sciences, Infectious and Immunologic Diseases Research Center, Cedars-Sinai Medical Center, Los Angeles, CA, USA., da Silva MDV; Department of Immunology, Parasitology and General Pathology, Londrina State University, Rodovia Celso Garcia Cid, Km 380, PR 445, Caixa Postal 10.011, Londrina, Paraná, 86057-970, Brazil., Rasquel-Oliveira FS; Department of Immunology, Parasitology and General Pathology, Londrina State University, Rodovia Celso Garcia Cid, Km 380, PR 445, Caixa Postal 10.011, Londrina, Paraná, 86057-970, Brazil.; Department of Vascular Biology Program, Department of Surgery, Boston Children's Hospital, Harvard Medical School, Karp Research Building, Boston, MA, USA., Zanoveli JM; Department of Pharmacology, Biological Science Sector, Federal University of Paraná, Curitiba, Paraná, Brazil., Fattori V; Department of Vascular Biology Program, Department of Surgery, Boston Children's Hospital, Harvard Medical School, Karp Research Building, Boston, MA, USA., Casagrande R; Department of Pharmaceutical Sciences, Londrina State University, Avenida Robert Koch, 60, Caixa Postal 10.011, Londrina, Paraná, 86039-440, Brazil., Verri WA Jr; Department of Immunology, Parasitology and General Pathology, Londrina State University, Rodovia Celso Garcia Cid, Km 380, PR 445, Caixa Postal 10.011, Londrina, Paraná, 86057-970, Brazil. waldiceujr@yahoo.com.br.
Source: Inflammation research : official journal of the European Histamine Research Society ... [et al.] [Inflamm Res] 2026 Apr 02; Vol. 75 (1). Date of Electronic Publication: 2026 Apr 02.
Publication Type: Journal Article
Journal Info: Publisher: Birkhäuser Country of Publication: Switzerland NLM ID: 9508160 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-908X (Electronic) Linking ISSN: 10233830 NLM ISO Abbreviation: Inflamm Res Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Protectin DX reduces inflammatory pain initiated by superoxide anion in mice: targeting leukocyte recruitment, oxidative stress, cytokine production and TRPV1<superscript>+</superscript> nociceptive sensory neuron activation.
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  Data: <searchLink fieldCode="AU" term="%22Carneiro+JA%22">Carneiro JA</searchLink>; Department of Immunology, Parasitology and General Pathology, Londrina State University, Rodovia Celso Garcia Cid, Km 380, PR 445, Caixa Postal 10.011, Londrina, Paraná, 86057-970, Brazil.<br /><searchLink fieldCode="AU" term="%22Bianchini+BHS%22">Bianchini BHS</searchLink>; Department of Immunology, Parasitology and General Pathology, Londrina State University, Rodovia Celso Garcia Cid, Km 380, PR 445, Caixa Postal 10.011, Londrina, Paraná, 86057-970, Brazil.<br /><searchLink fieldCode="AU" term="%22Martelossi-Cebinelli+G%22">Martelossi-Cebinelli G</searchLink>; Department of Immunology, Parasitology and General Pathology, Londrina State University, Rodovia Celso Garcia Cid, Km 380, PR 445, Caixa Postal 10.011, Londrina, Paraná, 86057-970, Brazil.<br /><searchLink fieldCode="AU" term="%22Artero+NA%22">Artero NA</searchLink>; Department of Immunology, Parasitology and General Pathology, Londrina State University, Rodovia Celso Garcia Cid, Km 380, PR 445, Caixa Postal 10.011, Londrina, Paraná, 86057-970, Brazil.<br /><searchLink fieldCode="AU" term="%22Maximiano+TKE%22">Maximiano TKE</searchLink>; Department of Immunology, Parasitology and General Pathology, Londrina State University, Rodovia Celso Garcia Cid, Km 380, PR 445, Caixa Postal 10.011, Londrina, Paraná, 86057-970, Brazil.<br /><searchLink fieldCode="AU" term="%22Franciosi+A%22">Franciosi A</searchLink>; Department of Immunology, Parasitology and General Pathology, Londrina State University, Rodovia Celso Garcia Cid, Km 380, PR 445, Caixa Postal 10.011, Londrina, Paraná, 86057-970, Brazil.<br /><searchLink fieldCode="AU" term="%22Dionisio+AM%22">Dionisio AM</searchLink>; Department of Immunology, Parasitology and General Pathology, Londrina State University, Rodovia Celso Garcia Cid, Km 380, PR 445, Caixa Postal 10.011, Londrina, Paraná, 86057-970, Brazil.<br /><searchLink fieldCode="AU" term="%22Yaekashi+KM%22">Yaekashi KM</searchLink>; Department of Immunology, Parasitology and General Pathology, Londrina State University, Rodovia Celso Garcia Cid, Km 380, PR 445, Caixa Postal 10.011, Londrina, Paraná, 86057-970, Brazil.<br /><searchLink fieldCode="AU" term="%22Carvalho+TT%22">Carvalho TT</searchLink>; Department of Immunology, Parasitology and General Pathology, Londrina State University, Rodovia Celso Garcia Cid, Km 380, PR 445, Caixa Postal 10.011, Londrina, Paraná, 86057-970, Brazil.; Department of Biomedical Sciences, Infectious and Immunologic Diseases Research Center, Cedars-Sinai Medical Center, Los Angeles, CA, USA.<br /><searchLink fieldCode="AU" term="%22da+Silva+MDV%22">da Silva MDV</searchLink>; Department of Immunology, Parasitology and General Pathology, Londrina State University, Rodovia Celso Garcia Cid, Km 380, PR 445, Caixa Postal 10.011, Londrina, Paraná, 86057-970, Brazil.<br /><searchLink fieldCode="AU" term="%22Rasquel-Oliveira+FS%22">Rasquel-Oliveira FS</searchLink>; Department of Immunology, Parasitology and General Pathology, Londrina State University, Rodovia Celso Garcia Cid, Km 380, PR 445, Caixa Postal 10.011, Londrina, Paraná, 86057-970, Brazil.; Department of Vascular Biology Program, Department of Surgery, Boston Children's Hospital, Harvard Medical School, Karp Research Building, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Zanoveli+JM%22">Zanoveli JM</searchLink>; Department of Pharmacology, Biological Science Sector, Federal University of Paraná, Curitiba, Paraná, Brazil.<br /><searchLink fieldCode="AU" term="%22Fattori+V%22">Fattori V</searchLink>; Department of Vascular Biology Program, Department of Surgery, Boston Children's Hospital, Harvard Medical School, Karp Research Building, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Casagrande+R%22">Casagrande R</searchLink>; Department of Pharmaceutical Sciences, Londrina State University, Avenida Robert Koch, 60, Caixa Postal 10.011, Londrina, Paraná, 86039-440, Brazil.<br /><searchLink fieldCode="AU" term="%22Verri+WA+Jr%22">Verri WA Jr</searchLink>; Department of Immunology, Parasitology and General Pathology, Londrina State University, Rodovia Celso Garcia Cid, Km 380, PR 445, Caixa Postal 10.011, Londrina, Paraná, 86057-970, Brazil. waldiceujr@yahoo.com.br.
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  Data: <searchLink fieldCode="JN" term="%229508160%22">Inflammation research : official journal of the European Histamine Research Society ... [et al.]</searchLink> [Inflamm Res] 2026 Apr 02; Vol. 75 (1). <i>Date of Electronic Publication: </i>2026 Apr 02.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Birkhäuser%22">Birkhäuser </searchLink><i>Country of Publication: </i>Switzerland <i>NLM ID: </i>9508160 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1420-908X (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2210233830%22">10233830 </searchLink><i>NLM ISO Abbreviation: </i>Inflamm Res <i>Subsets: </i>MEDLINE
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        Value: 10.1007/s00011-026-02234-5
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        Text: English
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      – TitleFull: Protectin DX reduces inflammatory pain initiated by superoxide anion in mice: targeting leukocyte recruitment, oxidative stress, cytokine production and TRPV1+ nociceptive sensory neuron activation.
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              Text: 2026 Apr 02
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