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Exploratory study of PD-1 inhibitors with or without ruxolitinib for the treatment of adult EBV-associated hemophagocytic lymphohistiocytosis: a real-world data-based preliminary investigation.

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Title: Exploratory study of PD-1 inhibitors with or without ruxolitinib for the treatment of adult EBV-associated hemophagocytic lymphohistiocytosis: a real-world data-based preliminary investigation.
Authors: Chen Z; Department of Hematology, Hunan Provincial People's Hospital, The First Affiliated Hospital of Hunan Normal University, Changsha, 410002, China., Li W; Department of Hematology, Hunan Provincial People's Hospital, The First Affiliated Hospital of Hunan Normal University, Changsha, 410002, China.; Hunan Normal University , Changsha, 410081, China., Liu C; Department of Hematology, Hunan Provincial People's Hospital, The First Affiliated Hospital of Hunan Normal University, Changsha, 410002, China., Chen J; Department of Hematology, Hunan Provincial People's Hospital, The First Affiliated Hospital of Hunan Normal University, Changsha, 410002, China., Tan X; Department of Hematology, Hunan Provincial People's Hospital, The First Affiliated Hospital of Hunan Normal University, Changsha, 410002, China., Li W; Department of Hematology, Hunan Provincial People's Hospital, The First Affiliated Hospital of Hunan Normal University, Changsha, 410002, China., Zhou C; Department of Hematology, Hunan Provincial People's Hospital, The First Affiliated Hospital of Hunan Normal University, Changsha, 410002, China., Li F; Department of Hematology, Hunan Provincial People's Hospital, The First Affiliated Hospital of Hunan Normal University, Changsha, 410002, China., Lei P; Laboratory of Hematology, Hunan Provincial People's Hospital,The First Affiliated Hospital of Hunan Normal University, Changsha, 410002, China., Zhou M; Department of Hematology, Hunan Provincial People's Hospital, The First Affiliated Hospital of Hunan Normal University, Changsha, 410002, China. Zhouming_0321@163.com.
Source: Clinical and experimental medicine [Clin Exp Med] 2026 Apr 02; Vol. 26 (1). Date of Electronic Publication: 2026 Apr 02.
Publication Type: Journal Article
Journal Info: Publisher: Springer-Verlag Italia Country of Publication: Italy NLM ID: 100973405 Publication Model: Electronic Cited Medium: Internet ISSN: 1591-9528 (Electronic) Linking ISSN: 15918890 NLM ISO Abbreviation: Clin Exp Med Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Exploratory study of PD-1 inhibitors with or without ruxolitinib for the treatment of adult EBV-associated hemophagocytic lymphohistiocytosis: a real-world data-based preliminary investigation.
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  Data: <searchLink fieldCode="AU" term="%22Chen+Z%22">Chen Z</searchLink>; Department of Hematology, Hunan Provincial People's Hospital, The First Affiliated Hospital of Hunan Normal University, Changsha, 410002, China.<br /><searchLink fieldCode="AU" term="%22Li+W%22">Li W</searchLink>; Department of Hematology, Hunan Provincial People's Hospital, The First Affiliated Hospital of Hunan Normal University, Changsha, 410002, China.; Hunan Normal University , Changsha, 410081, China.<br /><searchLink fieldCode="AU" term="%22Liu+C%22">Liu C</searchLink>; Department of Hematology, Hunan Provincial People's Hospital, The First Affiliated Hospital of Hunan Normal University, Changsha, 410002, China.<br /><searchLink fieldCode="AU" term="%22Chen+J%22">Chen J</searchLink>; Department of Hematology, Hunan Provincial People's Hospital, The First Affiliated Hospital of Hunan Normal University, Changsha, 410002, China.<br /><searchLink fieldCode="AU" term="%22Tan+X%22">Tan X</searchLink>; Department of Hematology, Hunan Provincial People's Hospital, The First Affiliated Hospital of Hunan Normal University, Changsha, 410002, China.<br /><searchLink fieldCode="AU" term="%22Li+W%22">Li W</searchLink>; Department of Hematology, Hunan Provincial People's Hospital, The First Affiliated Hospital of Hunan Normal University, Changsha, 410002, China.<br /><searchLink fieldCode="AU" term="%22Zhou+C%22">Zhou C</searchLink>; Department of Hematology, Hunan Provincial People's Hospital, The First Affiliated Hospital of Hunan Normal University, Changsha, 410002, China.<br /><searchLink fieldCode="AU" term="%22Li+F%22">Li F</searchLink>; Department of Hematology, Hunan Provincial People's Hospital, The First Affiliated Hospital of Hunan Normal University, Changsha, 410002, China.<br /><searchLink fieldCode="AU" term="%22Lei+P%22">Lei P</searchLink>; Laboratory of Hematology, Hunan Provincial People's Hospital,The First Affiliated Hospital of Hunan Normal University, Changsha, 410002, China.<br /><searchLink fieldCode="AU" term="%22Zhou+M%22">Zhou M</searchLink>; Department of Hematology, Hunan Provincial People's Hospital, The First Affiliated Hospital of Hunan Normal University, Changsha, 410002, China. Zhouming_0321@163.com.
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  Data: <searchLink fieldCode="JN" term="%22100973405%22">Clinical and experimental medicine</searchLink> [Clin Exp Med] 2026 Apr 02; Vol. 26 (1). <i>Date of Electronic Publication: </i>2026 Apr 02.
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        Value: 10.1007/s10238-026-02136-0
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        Text: English
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      – TitleFull: Exploratory study of PD-1 inhibitors with or without ruxolitinib for the treatment of adult EBV-associated hemophagocytic lymphohistiocytosis: a real-world data-based preliminary investigation.
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              Text: 2026 Apr 02
              Type: published
              Y: 2026
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