Repurposing rosmarinic acid as an anti-colorectal cancer agent through bolstering T cell anti-tumor immunity by enhancing activation of MEK1-mediated TCR signaling.

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Title: Repurposing rosmarinic acid as an anti-colorectal cancer agent through bolstering T cell anti-tumor immunity by enhancing activation of MEK1-mediated TCR signaling.
Authors: Kang Z; Department of Colorectal Surgery, Changhai Hospital, Naval Medical University, Shanghai, 200433, China., Li X; Department of Colorectal Surgery, Changhai Hospital, Naval Medical University, Shanghai, 200433, China., Ma X; Department of Colorectal Surgery, Changhai Hospital, Naval Medical University, Shanghai, 200433, China., Yan F; Department of Colorectal Surgery, Changhai Hospital, Naval Medical University, Shanghai, 200433, China. feihu_1989@163.com., Wang Z; Department of Colorectal Surgery, Changhai Hospital, Naval Medical University, Shanghai, 200433, China. dr_wangzhen@163.com.
Source: Cancer immunology, immunotherapy : CII [Cancer Immunol Immunother] 2026 Apr 02; Vol. 75 (4). Date of Electronic Publication: 2026 Apr 02.
Publication Type: Journal Article
Journal Info: Publisher: Springer Verlag Country of Publication: Germany NLM ID: 8605732 Publication Model: Electronic Cited Medium: Internet ISSN: 1432-0851 (Electronic) Linking ISSN: 03407004 NLM ISO Abbreviation: Cancer Immunol Immunother Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1432-0851
DOI:10.1007/s00262-026-04366-3