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Loss of ovarian function and estrogen therapy remodel the brain's synaptic and metabolic proteome.

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Title: Loss of ovarian function and estrogen therapy remodel the brain's synaptic and metabolic proteome.
Authors: Salathe SF; Department of Cell Biology and Physiology, University of Kansas Medical Center, Kansas City, Kansas, United States., Franczak E; Department of Cell Biology and Physiology, University of Kansas Medical Center, Kansas City, Kansas, United States., Busick Z; Department of Cell Biology and Physiology, University of Kansas Medical Center, Kansas City, Kansas, United States., Boakye FB; Department of Cell Biology and Physiology, University of Kansas Medical Center, Kansas City, Kansas, United States., Allen J; Department of Cell Biology and Physiology, University of Kansas Medical Center, Kansas City, Kansas, United States., Lutkewitte A; Internal Medicine, Division of Endocrinology and Clinical Pharmacology and KU Diabetes Institute, University of Kansas Medical Center, Kansas City, Kansas, United States.; Kansas Center for Metabolism and Obesity Research, University of Kansas Medical Center, Kansas City, Kansas, United States.; The University of Kansas Diabetes Institute, Kansas City, Kansas, United States., Wilkins H; Department of Neurology, University of Kansas Medical Center, Kansas City, Kansas, United States.; University of Kansas Alzheimer's Disease Center, University of Kansas Medical Center, Kansas City, Kansas, United States.; Department of Biochemistry and Molecular Biology, University of Kansas Medical Center, Kansas City, Kansas, United States., Thyfault J; Department of Cell Biology and Physiology, University of Kansas Medical Center, Kansas City, Kansas, United States.; Internal Medicine, Division of Endocrinology and Clinical Pharmacology and KU Diabetes Institute, University of Kansas Medical Center, Kansas City, Kansas, United States.; Kansas Center for Metabolism and Obesity Research, University of Kansas Medical Center, Kansas City, Kansas, United States.; The University of Kansas Diabetes Institute, Kansas City, Kansas, United States.; Department of Neurology, University of Kansas Medical Center, Kansas City, Kansas, United States.; University of Kansas Alzheimer's Disease Center, University of Kansas Medical Center, Kansas City, Kansas, United States., Kugler BA; Department of Cell Biology and Physiology, University of Kansas Medical Center, Kansas City, Kansas, United States.
Source: American journal of physiology. Regulatory, integrative and comparative physiology [Am J Physiol Regul Integr Comp Physiol] 2026 May 01; Vol. 330 (5), pp. R489-R500. Date of Electronic Publication: 2026 Apr 02.
Publication Type: Journal Article
Journal Info: Publisher: American Physiological Society Country of Publication: United States NLM ID: 100901230 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1522-1490 (Electronic) Linking ISSN: 03636119 NLM ISO Abbreviation: Am J Physiol Regul Integr Comp Physiol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Loss of ovarian function and estrogen therapy remodel the brain's synaptic and metabolic proteome.
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  Data: <searchLink fieldCode="AU" term="%22Salathe+SF%22">Salathe SF</searchLink>; Department of Cell Biology and Physiology, University of Kansas Medical Center, Kansas City, Kansas, United States.<br /><searchLink fieldCode="AU" term="%22Franczak+E%22">Franczak E</searchLink>; Department of Cell Biology and Physiology, University of Kansas Medical Center, Kansas City, Kansas, United States.<br /><searchLink fieldCode="AU" term="%22Busick+Z%22">Busick Z</searchLink>; Department of Cell Biology and Physiology, University of Kansas Medical Center, Kansas City, Kansas, United States.<br /><searchLink fieldCode="AU" term="%22Boakye+FB%22">Boakye FB</searchLink>; Department of Cell Biology and Physiology, University of Kansas Medical Center, Kansas City, Kansas, United States.<br /><searchLink fieldCode="AU" term="%22Allen+J%22">Allen J</searchLink>; Department of Cell Biology and Physiology, University of Kansas Medical Center, Kansas City, Kansas, United States.<br /><searchLink fieldCode="AU" term="%22Lutkewitte+A%22">Lutkewitte A</searchLink>; Internal Medicine, Division of Endocrinology and Clinical Pharmacology and KU Diabetes Institute, University of Kansas Medical Center, Kansas City, Kansas, United States.; Kansas Center for Metabolism and Obesity Research, University of Kansas Medical Center, Kansas City, Kansas, United States.; The University of Kansas Diabetes Institute, Kansas City, Kansas, United States.<br /><searchLink fieldCode="AU" term="%22Wilkins+H%22">Wilkins H</searchLink>; Department of Neurology, University of Kansas Medical Center, Kansas City, Kansas, United States.; University of Kansas Alzheimer's Disease Center, University of Kansas Medical Center, Kansas City, Kansas, United States.; Department of Biochemistry and Molecular Biology, University of Kansas Medical Center, Kansas City, Kansas, United States.<br /><searchLink fieldCode="AU" term="%22Thyfault+J%22">Thyfault J</searchLink>; Department of Cell Biology and Physiology, University of Kansas Medical Center, Kansas City, Kansas, United States.; Internal Medicine, Division of Endocrinology and Clinical Pharmacology and KU Diabetes Institute, University of Kansas Medical Center, Kansas City, Kansas, United States.; Kansas Center for Metabolism and Obesity Research, University of Kansas Medical Center, Kansas City, Kansas, United States.; The University of Kansas Diabetes Institute, Kansas City, Kansas, United States.; Department of Neurology, University of Kansas Medical Center, Kansas City, Kansas, United States.; University of Kansas Alzheimer's Disease Center, University of Kansas Medical Center, Kansas City, Kansas, United States.<br /><searchLink fieldCode="AU" term="%22Kugler+BA%22">Kugler BA</searchLink>; Department of Cell Biology and Physiology, University of Kansas Medical Center, Kansas City, Kansas, United States.
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  Data: <searchLink fieldCode="JN" term="%22100901230%22">American journal of physiology. Regulatory, integrative and comparative physiology</searchLink> [Am J Physiol Regul Integr Comp Physiol] 2026 May 01; Vol. 330 (5), pp. R489-R500. <i>Date of Electronic Publication: </i>2026 Apr 02.
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        Value: 10.1152/ajpregu.00031.2026
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              Text: 2026 May 01
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