Molecular variants, clonal evolution and clinical relevance in pediatric and adult T-cell lymphoblastic neoplasia.

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Title: Molecular variants, clonal evolution and clinical relevance in pediatric and adult T-cell lymphoblastic neoplasia.
Authors: Sandmann S; Institute of Medical Data Science, Otto-von-Guericke-University, Magdeburg, Germany. sarah.sandmann@med.ovgu.de., Te Vrugt M; Pediatric Hematology and Oncology and NHL-BFM study center, University Hospital Muenster, Muenster, Germany., Randau G; Pediatric Hematology and Oncology and NHL-BFM study center, University Hospital Muenster, Muenster, Germany., Beder T; A Clinical Research Unit 'CATCH ALL' (KFO 5010/1) funded by the Deutsche Forschungsgemeinschaft, Kiel, Germany., Neumann M; Department of Medicine II, Hematology and Oncology, University Hospital Schleswig-Holstein, Kiel, Germany., Lange T; Institute of Medical Data Science, Otto-von-Guericke-University, Magdeburg, Germany.; Department of Psychiatry, University of Muenster, Muenster, Germany., Alfert A; Pediatric Hematology and Oncology and NHL-BFM study center, University Hospital Muenster, Muenster, Germany., Mueller S; Pediatric Hematology and Oncology and NHL-BFM study center, University Hospital Muenster, Muenster, Germany., Hotfilder M; Pediatric Hematology and Oncology and NHL-BFM study center, University Hospital Muenster, Muenster, Germany., Rossi C; Clinic for Pediatric Oncology, Hematology, Immunology, and Pneumology, Center for Pediatric and Adolescent Medicine, University Hospital Heidelberg, Heidelberg, Germany., Eckert C; Department of Pediatric Oncology/Hematology, Charité Universitaetsmedizin Berlin, Berlin, Germany., Moericke A; Department of Pediatrics I, Pediatric Hematology/Oncology, ALL-BFM Study Group, Christian Albrechts University Kiel and University Hospital Schleswig-Holstein, Kiel, Germany., Horns JM; Department of Medicine II, Hematology and Oncology, University Hospital Schleswig-Holstein, Kiel, Germany., Zimmermann M; Department of Pediatric Hematology and Oncology, Hannover Medical School, Hannover, Germany., Varghese J; Institute of Medical Data Science, Otto-von-Guericke-University, Magdeburg, Germany., Brüggemann M; Department of Medicine II, Hematology and Oncology, University Hospital Schleswig-Holstein, Kiel, Germany., Burkhardt B; Pediatric Hematology and Oncology and NHL-BFM study center, University Hospital Muenster, Muenster, Germany. birgit.burkhardt@ukmuenster.de.
Source: Blood cancer journal [Blood Cancer J] 2026 Apr 02; Vol. 16 (1). Date of Electronic Publication: 2026 Apr 02.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: United States NLM ID: 101568469 Publication Model: Electronic Cited Medium: Internet ISSN: 2044-5385 (Electronic) Linking ISSN: 20445385 NLM ISO Abbreviation: Blood Cancer J Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:2044-5385
DOI:10.1038/s41408-026-01488-w