Zoledronic acid enhances the antitumor efficacy of the PSMA CAR-T cells for bone tumors, but impedes the ability to control metastases of prostate cancer in mice.
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| Title: | Zoledronic acid enhances the antitumor efficacy of the PSMA CAR-T cells for bone tumors, but impedes the ability to control metastases of prostate cancer in mice. |
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| Authors: | Li D; Department of Biotherapy, the State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, and Collaborative Innovation Center for Biotherapy, Chengdu, China., Gu X; Department of Biotherapy, the State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, and Collaborative Innovation Center for Biotherapy, Chengdu, China., Li J; Department of Biotherapy, the State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, and Collaborative Innovation Center for Biotherapy, Chengdu, China., Huang Y; Department of Biotherapy, the State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, and Collaborative Innovation Center for Biotherapy, Chengdu, China.; Department of Laboratory Medicine, General Hospital of Western Theater Command of PLA, Chengdu, Sichuan, China., Zhou WL; Department of Biotherapy, the State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, and Collaborative Innovation Center for Biotherapy, Chengdu, China., Li J; Department of Biotherapy, the State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, and Collaborative Innovation Center for Biotherapy, Chengdu, China., Wang F; Department of Biotherapy, the State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, and Collaborative Innovation Center for Biotherapy, Chengdu, China., Yan F; Department of Biotherapy, the State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, and Collaborative Innovation Center for Biotherapy, Chengdu, China., Gao H; Department of Biotherapy, the State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, and Collaborative Innovation Center for Biotherapy, Chengdu, China., Ying X; Department of Biotherapy, the State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, and Collaborative Innovation Center for Biotherapy, Chengdu, China., Li Y; Department of Biotherapy, the State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, and Collaborative Innovation Center for Biotherapy, Chengdu, China., Qi S; Department of Biotherapy, the State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, and Collaborative Innovation Center for Biotherapy, Chengdu, China., Zhu Y; Department of Biotherapy, Cancer center, West China Hospital, Sichuan University, Chengdu, China., Liu J; Department of Biotherapy, Cancer center, West China Hospital, Sichuan University, Chengdu, China., Wang W; Department of Biotherapy, the State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, and Collaborative Innovation Center for Biotherapy, Chengdu, China. weiwang@scu.edu.cn. |
| Source: | Cancer gene therapy [Cancer Gene Ther] 2026 Apr 02. Date of Electronic Publication: 2026 Apr 02. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Publishing Group Country of Publication: England NLM ID: 9432230 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5500 (Electronic) Linking ISSN: 09291903 NLM ISO Abbreviation: Cancer Gene Ther Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 41927852 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Zoledronic acid enhances the antitumor efficacy of the PSMA CAR-T cells for bone tumors, but impedes the ability to control metastases of prostate cancer in mice. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Li+D%22">Li D</searchLink>; Department of Biotherapy, the State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, and Collaborative Innovation Center for Biotherapy, Chengdu, China.<br /><searchLink fieldCode="AU" term="%22Gu+X%22">Gu X</searchLink>; Department of Biotherapy, the State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, and Collaborative Innovation Center for Biotherapy, Chengdu, China.<br /><searchLink fieldCode="AU" term="%22Li+J%22">Li J</searchLink>; Department of Biotherapy, the State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, and Collaborative Innovation Center for Biotherapy, Chengdu, China.<br /><searchLink fieldCode="AU" term="%22Huang+Y%22">Huang Y</searchLink>; Department of Biotherapy, the State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, and Collaborative Innovation Center for Biotherapy, Chengdu, China.; Department of Laboratory Medicine, General Hospital of Western Theater Command of PLA, Chengdu, Sichuan, China.<br /><searchLink fieldCode="AU" term="%22Zhou+WL%22">Zhou WL</searchLink>; Department of Biotherapy, the State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, and Collaborative Innovation Center for Biotherapy, Chengdu, China.<br /><searchLink fieldCode="AU" term="%22Li+J%22">Li J</searchLink>; Department of Biotherapy, the State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, and Collaborative Innovation Center for Biotherapy, Chengdu, China.<br /><searchLink fieldCode="AU" term="%22Wang+F%22">Wang F</searchLink>; Department of Biotherapy, the State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, and Collaborative Innovation Center for Biotherapy, Chengdu, China.<br /><searchLink fieldCode="AU" term="%22Yan+F%22">Yan F</searchLink>; Department of Biotherapy, the State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, and Collaborative Innovation Center for Biotherapy, Chengdu, China.<br /><searchLink fieldCode="AU" term="%22Gao+H%22">Gao H</searchLink>; Department of Biotherapy, the State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, and Collaborative Innovation Center for Biotherapy, Chengdu, China.<br /><searchLink fieldCode="AU" term="%22Ying+X%22">Ying X</searchLink>; Department of Biotherapy, the State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, and Collaborative Innovation Center for Biotherapy, Chengdu, China.<br /><searchLink fieldCode="AU" term="%22Li+Y%22">Li Y</searchLink>; Department of Biotherapy, the State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, and Collaborative Innovation Center for Biotherapy, Chengdu, China.<br /><searchLink fieldCode="AU" term="%22Qi+S%22">Qi S</searchLink>; Department of Biotherapy, the State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, and Collaborative Innovation Center for Biotherapy, Chengdu, China.<br /><searchLink fieldCode="AU" term="%22Zhu+Y%22">Zhu Y</searchLink>; Department of Biotherapy, Cancer center, West China Hospital, Sichuan University, Chengdu, China.<br /><searchLink fieldCode="AU" term="%22Liu+J%22">Liu J</searchLink>; Department of Biotherapy, Cancer center, West China Hospital, Sichuan University, Chengdu, China.<br /><searchLink fieldCode="AU" term="%22Wang+W%22">Wang W</searchLink>; Department of Biotherapy, the State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, and Collaborative Innovation Center for Biotherapy, Chengdu, China. weiwang@scu.edu.cn. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%229432230%22">Cancer gene therapy</searchLink> [Cancer Gene Ther] 2026 Apr 02. <i>Date of Electronic Publication: </i>2026 Apr 02. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Publishing+Group%22">Nature Publishing Group </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>9432230 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1476-5500 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2209291903%22">09291903 </searchLink><i>NLM ISO Abbreviation: </i>Cancer Gene Ther <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=41927852 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1038/s41417-026-01025-8 Languages: – Code: eng Text: English Titles: – TitleFull: Zoledronic acid enhances the antitumor efficacy of the PSMA CAR-T cells for bone tumors, but impedes the ability to control metastases of prostate cancer in mice. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Li D – PersonEntity: Name: NameFull: Gu X – PersonEntity: Name: NameFull: Li J – PersonEntity: Name: NameFull: Huang Y – PersonEntity: Name: NameFull: Zhou WL – PersonEntity: Name: NameFull: Li J – PersonEntity: Name: NameFull: Wang F – PersonEntity: Name: NameFull: Yan F – PersonEntity: Name: NameFull: Gao H – PersonEntity: Name: NameFull: Ying X – PersonEntity: Name: NameFull: Li Y – PersonEntity: Name: NameFull: Qi S – PersonEntity: Name: NameFull: Zhu Y – PersonEntity: Name: NameFull: Liu J – PersonEntity: Name: NameFull: Wang W IsPartOfRelationships: – BibEntity: Dates: – D: 02 M: 04 Text: 2026 Apr 02 Type: published Y: 2026 Identifiers: – Type: issn-electronic Value: 1476-5500 Titles: – TitleFull: Cancer gene therapy Type: main |
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