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Chronic kidney disease induces a distinct lipidomic signature and accelerates atherosclerosis progression in a novel minipig model.

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Title: Chronic kidney disease induces a distinct lipidomic signature and accelerates atherosclerosis progression in a novel minipig model.
Authors: Bermúdez-López M; Department of Experimental Medicine, University of Lleida (UdL), Lleida, Spain. mbermudez@irblleida.cat.; Vascular and Renal Translational Research Group, Institute for Research in Biomedicine of Lleida (IRBLleida), RICORS2040, Madrid, Lleida, Spain. mbermudez@irblleida.cat., Nogales P; Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC), Madrid, Spain.; Department of Clinical Medicine, Aarhus University, Aarhus, Denmark., Martí-Antonio M; Vascular and Renal Translational Research Group, Institute for Research in Biomedicine of Lleida (IRBLleida), RICORS2040, Madrid, Lleida, Spain., Castro-Boqué E; Vascular and Renal Translational Research Group, Institute for Research in Biomedicine of Lleida (IRBLleida), RICORS2040, Madrid, Lleida, Spain., de Lamo VM; Vascular and Renal Translational Research Group, Institute for Research in Biomedicine of Lleida (IRBLleida), RICORS2040, Madrid, Lleida, Spain., Beà-Menchón L; Vascular and Renal Translational Research Group, Institute for Research in Biomedicine of Lleida (IRBLleida), RICORS2040, Madrid, Lleida, Spain., Luis-Lima S; Department of Laboratory Medicine, Complejo Hospitalario Universitario de Canarias, Santa Cruz de Tenerife, Spain., Porrini E; Instituto Tecnologías Biomédicas, University of La Laguna, Tenerife, Spain., Sanchez-Salguero X; Department of Animal Science, ETSEAFIV, University of Lleida, Lleida, Spain., Jové M; Department of Experimental Medicine, University of Lleida (UdL), Lleida, Spain.; Lleida Biomedical Research Institute (IRBLleida), Lleida, Spain., Obis E; Department of Experimental Medicine, University of Lleida (UdL), Lleida, Spain.; Lleida Biomedical Research Institute (IRBLleida), Lleida, Spain., Mota-Martorell N; Department of Experimental Medicine, University of Lleida (UdL), Lleida, Spain.; Lleida Biomedical Research Institute (IRBLleida), Lleida, Spain., Pérez-Gómez A; Vascular and Renal Translational Research Group, Institute for Research in Biomedicine of Lleida (IRBLleida), RICORS2040, Madrid, Lleida, Spain., Garcia-Carrasco A; Vascular and Renal Translational Research Group, Institute for Research in Biomedicine of Lleida (IRBLleida), RICORS2040, Madrid, Lleida, Spain., Bozic M; Vascular and Renal Translational Research Group, Institute for Research in Biomedicine of Lleida (IRBLleida), RICORS2040, Madrid, Lleida, Spain., Guajardo J; Vascular and Renal Translational Research Group, Institute for Research in Biomedicine of Lleida (IRBLleida), RICORS2040, Madrid, Lleida, Spain., Pérez-Sánchez CJ; Biostatistics Unit, Faculty of Veterinary Medicine, University of Extremadura, Cáceres, Spain., Cambray S; Basic Medical Sciences Department, Serra Hunter Lecturer, University of Lleida (UdL), Lleida, Spain., Amigó N; Biosfer Teslab, Reus, Spain. Department of Basic Medical Sciences, Universitat Rovira i Virgili (URV), Institut d'Investigació Sanitària Pere Virgili (IISPV), Reus, Spain.; Centro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), Instituto de Salud Carlos III (ISCIII), Madrid, Spain., Pamplona R; Department of Experimental Medicine, University of Lleida (UdL), Lleida, Spain.; Lleida Biomedical Research Institute (IRBLleida), Lleida, Spain., Bentzon JF; Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC), Madrid, Spain.; Steno Diabetes Center Aarhus and Department of Cardiology, Aarhus University Hospital, Aarhus, Denmark., Valdivielso JM; Vascular and Renal Translational Research Group, Institute for Research in Biomedicine of Lleida (IRBLleida), RICORS2040, Madrid, Lleida, Spain. josemanuel.valdivielso@udl.cat.
Source: Laboratory animal research [Lab Anim Res] 2026 Apr 02; Vol. 42 (1). Date of Electronic Publication: 2026 Apr 02.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central, Ltd Country of Publication: England NLM ID: 101560684 Publication Model: Electronic Cited Medium: Print ISSN: 1738-6055 (Print) Linking ISSN: 17386055 NLM ISO Abbreviation: Lab Anim Res Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Chronic kidney disease induces a distinct lipidomic signature and accelerates atherosclerosis progression in a novel minipig model.
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  Data: <searchLink fieldCode="AU" term="%22Bermúdez-López+M%22">Bermúdez-López M</searchLink>; Department of Experimental Medicine, University of Lleida (UdL), Lleida, Spain. mbermudez@irblleida.cat.; Vascular and Renal Translational Research Group, Institute for Research in Biomedicine of Lleida (IRBLleida), RICORS2040, Madrid, Lleida, Spain. mbermudez@irblleida.cat.<br /><searchLink fieldCode="AU" term="%22Nogales+P%22">Nogales P</searchLink>; Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC), Madrid, Spain.; Department of Clinical Medicine, Aarhus University, Aarhus, Denmark.<br /><searchLink fieldCode="AU" term="%22Martí-Antonio+M%22">Martí-Antonio M</searchLink>; Vascular and Renal Translational Research Group, Institute for Research in Biomedicine of Lleida (IRBLleida), RICORS2040, Madrid, Lleida, Spain.<br /><searchLink fieldCode="AU" term="%22Castro-Boqué+E%22">Castro-Boqué E</searchLink>; Vascular and Renal Translational Research Group, Institute for Research in Biomedicine of Lleida (IRBLleida), RICORS2040, Madrid, Lleida, Spain.<br /><searchLink fieldCode="AU" term="%22de+Lamo+VM%22">de Lamo VM</searchLink>; Vascular and Renal Translational Research Group, Institute for Research in Biomedicine of Lleida (IRBLleida), RICORS2040, Madrid, Lleida, Spain.<br /><searchLink fieldCode="AU" term="%22Beà-Menchón+L%22">Beà-Menchón L</searchLink>; Vascular and Renal Translational Research Group, Institute for Research in Biomedicine of Lleida (IRBLleida), RICORS2040, Madrid, Lleida, Spain.<br /><searchLink fieldCode="AU" term="%22Luis-Lima+S%22">Luis-Lima S</searchLink>; Department of Laboratory Medicine, Complejo Hospitalario Universitario de Canarias, Santa Cruz de Tenerife, Spain.<br /><searchLink fieldCode="AU" term="%22Porrini+E%22">Porrini E</searchLink>; Instituto Tecnologías Biomédicas, University of La Laguna, Tenerife, Spain.<br /><searchLink fieldCode="AU" term="%22Sanchez-Salguero+X%22">Sanchez-Salguero X</searchLink>; Department of Animal Science, ETSEAFIV, University of Lleida, Lleida, Spain.<br /><searchLink fieldCode="AU" term="%22Jové+M%22">Jové M</searchLink>; Department of Experimental Medicine, University of Lleida (UdL), Lleida, Spain.; Lleida Biomedical Research Institute (IRBLleida), Lleida, Spain.<br /><searchLink fieldCode="AU" term="%22Obis+E%22">Obis E</searchLink>; Department of Experimental Medicine, University of Lleida (UdL), Lleida, Spain.; Lleida Biomedical Research Institute (IRBLleida), Lleida, Spain.<br /><searchLink fieldCode="AU" term="%22Mota-Martorell+N%22">Mota-Martorell N</searchLink>; Department of Experimental Medicine, University of Lleida (UdL), Lleida, Spain.; Lleida Biomedical Research Institute (IRBLleida), Lleida, Spain.<br /><searchLink fieldCode="AU" term="%22Pérez-Gómez+A%22">Pérez-Gómez A</searchLink>; Vascular and Renal Translational Research Group, Institute for Research in Biomedicine of Lleida (IRBLleida), RICORS2040, Madrid, Lleida, Spain.<br /><searchLink fieldCode="AU" term="%22Garcia-Carrasco+A%22">Garcia-Carrasco A</searchLink>; Vascular and Renal Translational Research Group, Institute for Research in Biomedicine of Lleida (IRBLleida), RICORS2040, Madrid, Lleida, Spain.<br /><searchLink fieldCode="AU" term="%22Bozic+M%22">Bozic M</searchLink>; Vascular and Renal Translational Research Group, Institute for Research in Biomedicine of Lleida (IRBLleida), RICORS2040, Madrid, Lleida, Spain.<br /><searchLink fieldCode="AU" term="%22Guajardo+J%22">Guajardo J</searchLink>; Vascular and Renal Translational Research Group, Institute for Research in Biomedicine of Lleida (IRBLleida), RICORS2040, Madrid, Lleida, Spain.<br /><searchLink fieldCode="AU" term="%22Pérez-Sánchez+CJ%22">Pérez-Sánchez CJ</searchLink>; Biostatistics Unit, Faculty of Veterinary Medicine, University of Extremadura, Cáceres, Spain.<br /><searchLink fieldCode="AU" term="%22Cambray+S%22">Cambray S</searchLink>; Basic Medical Sciences Department, Serra Hunter Lecturer, University of Lleida (UdL), Lleida, Spain.<br /><searchLink fieldCode="AU" term="%22Amigó+N%22">Amigó N</searchLink>; Biosfer Teslab, Reus, Spain. Department of Basic Medical Sciences, Universitat Rovira i Virgili (URV), Institut d'Investigació Sanitària Pere Virgili (IISPV), Reus, Spain.; Centro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), Instituto de Salud Carlos III (ISCIII), Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Pamplona+R%22">Pamplona R</searchLink>; Department of Experimental Medicine, University of Lleida (UdL), Lleida, Spain.; Lleida Biomedical Research Institute (IRBLleida), Lleida, Spain.<br /><searchLink fieldCode="AU" term="%22Bentzon+JF%22">Bentzon JF</searchLink>; Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC), Madrid, Spain.; Steno Diabetes Center Aarhus and Department of Cardiology, Aarhus University Hospital, Aarhus, Denmark.<br /><searchLink fieldCode="AU" term="%22Valdivielso+JM%22">Valdivielso JM</searchLink>; Vascular and Renal Translational Research Group, Institute for Research in Biomedicine of Lleida (IRBLleida), RICORS2040, Madrid, Lleida, Spain. josemanuel.valdivielso@udl.cat.
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  Data: <searchLink fieldCode="JN" term="%22101560684%22">Laboratory animal research</searchLink> [Lab Anim Res] 2026 Apr 02; Vol. 42 (1). <i>Date of Electronic Publication: </i>2026 Apr 02.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22BioMed+Central%2C+Ltd%22">BioMed Central, Ltd </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101560684 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Print <i>ISSN: </i>1738-6055 (Print) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2217386055%22">17386055 </searchLink><i>NLM ISO Abbreviation: </i>Lab Anim Res <i>Subsets: </i>PubMed not MEDLINE
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