Spike-in probe-enhanced single-cell RNA-seq reveals post-infusion transcriptomic remodeling of "prime-and-kill" synNotch-CAR-T cells.

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Title: Spike-in probe-enhanced single-cell RNA-seq reveals post-infusion transcriptomic remodeling of "prime-and-kill" synNotch-CAR-T cells.
Authors: Nejo T, Watchmaker PB, Simic MS, Yamamichi A, Lakshmanachetty S, Zhao A, Lu J, Gallus M, Benway HL, Zhu R, Almeida R, Lim WA, Okada H
Source: BioRxiv : the preprint server for biology [bioRxiv] 2026 Mar 29. Date of Electronic Publication: 2026 Mar 29.
Publication Type: Journal Article; Preprint
Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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Header DbId: mdl
DbLabel: MEDLINE Ultimate
An: 41929125
AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
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  Data: Spike-in probe-enhanced single-cell RNA-seq reveals post-infusion transcriptomic remodeling of "prime-and-kill" synNotch-CAR-T cells.
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  Data: <searchLink fieldCode="JN" term="%22101680187%22">BioRxiv : the preprint server for biology</searchLink> [bioRxiv] 2026 Mar 29. <i>Date of Electronic Publication: </i>2026 Mar 29.
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  Data: <i>Country of Publication: </i>United States <i>NLM ID: </i>101680187 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2692-8205 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2226928205%22">26928205 </searchLink><i>NLM ISO Abbreviation: </i>bioRxiv <i>Subsets: </i>PubMed not MEDLINE
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        Value: 10.64898/2026.03.26.713760
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      – Code: eng
        Text: English
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      – TitleFull: Spike-in probe-enhanced single-cell RNA-seq reveals post-infusion transcriptomic remodeling of "prime-and-kill" synNotch-CAR-T cells.
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            NameFull: Nejo T
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          Dates:
            – D: 29
              M: 03
              Text: 2026 Mar 29
              Type: published
              Y: 2026
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