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Double negative T cells (CD4-/CD8-) are associated with Trypanosoma cruzi persistence in the mouse colon during chronic Chagas disease.

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Title: Double negative T cells (CD4-/CD8-) are associated with Trypanosoma cruzi persistence in the mouse colon during chronic Chagas disease.
Authors: Cho JS; Laboratory of Emerging Pathogens, Division of Emerging and Transfusion Transmitted Diseases, Office of Blood Research and Review, Center for Biologics Evaluation and Research, Food and Drug Administration, Silver Spring, MD, United States., Kumar S; Laboratory of Emerging Pathogens, Division of Emerging and Transfusion Transmitted Diseases, Office of Blood Research and Review, Center for Biologics Evaluation and Research, Food and Drug Administration, Silver Spring, MD, United States., Silberstein E; Laboratory of Emerging Pathogens, Division of Emerging and Transfusion Transmitted Diseases, Office of Blood Research and Review, Center for Biologics Evaluation and Research, Food and Drug Administration, Silver Spring, MD, United States., Ma X; Laboratory of Immunobiochemistry, Division of Bacterial, Parasitic & Allergenic Products, Office of Vaccines Research and Review, Center for Biologics Evaluation and Research, Food and Drug Administration, Silver Spring, MD, United States., Zhovmer A; Laboratory of Immunobiochemistry, Division of Bacterial, Parasitic & Allergenic Products, Office of Vaccines Research and Review, Center for Biologics Evaluation and Research, Food and Drug Administration, Silver Spring, MD, United States., Debrabant A; Laboratory of Emerging Pathogens, Division of Emerging and Transfusion Transmitted Diseases, Office of Blood Research and Review, Center for Biologics Evaluation and Research, Food and Drug Administration, Silver Spring, MD, United States.
Source: Frontiers in immunology [Front Immunol] 2026 Mar 18; Vol. 17, pp. 1761769. Date of Electronic Publication: 2026 Mar 18 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Double negative T cells (CD4<superscript>-</superscript>/CD8<superscript>-</superscript>) are associated with Trypanosoma cruzi persistence in the mouse colon during chronic Chagas disease.
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  Data: <searchLink fieldCode="AU" term="%22Cho+JS%22">Cho JS</searchLink>; Laboratory of Emerging Pathogens, Division of Emerging and Transfusion Transmitted Diseases, Office of Blood Research and Review, Center for Biologics Evaluation and Research, Food and Drug Administration, Silver Spring, MD, United States.<br /><searchLink fieldCode="AU" term="%22Kumar+S%22">Kumar S</searchLink>; Laboratory of Emerging Pathogens, Division of Emerging and Transfusion Transmitted Diseases, Office of Blood Research and Review, Center for Biologics Evaluation and Research, Food and Drug Administration, Silver Spring, MD, United States.<br /><searchLink fieldCode="AU" term="%22Silberstein+E%22">Silberstein E</searchLink>; Laboratory of Emerging Pathogens, Division of Emerging and Transfusion Transmitted Diseases, Office of Blood Research and Review, Center for Biologics Evaluation and Research, Food and Drug Administration, Silver Spring, MD, United States.<br /><searchLink fieldCode="AU" term="%22Ma+X%22">Ma X</searchLink>; Laboratory of Immunobiochemistry, Division of Bacterial, Parasitic & Allergenic Products, Office of Vaccines Research and Review, Center for Biologics Evaluation and Research, Food and Drug Administration, Silver Spring, MD, United States.<br /><searchLink fieldCode="AU" term="%22Zhovmer+A%22">Zhovmer A</searchLink>; Laboratory of Immunobiochemistry, Division of Bacterial, Parasitic & Allergenic Products, Office of Vaccines Research and Review, Center for Biologics Evaluation and Research, Food and Drug Administration, Silver Spring, MD, United States.<br /><searchLink fieldCode="AU" term="%22Debrabant+A%22">Debrabant A</searchLink>; Laboratory of Emerging Pathogens, Division of Emerging and Transfusion Transmitted Diseases, Office of Blood Research and Review, Center for Biologics Evaluation and Research, Food and Drug Administration, Silver Spring, MD, United States.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Frontiers+Research+Foundation]%22">Frontiers Research Foundation] </searchLink><i>Country of Publication: </i>Switzerland <i>NLM ID: </i>101560960 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Internet <i>ISSN: </i>1664-3224 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2216643224%22">16643224 </searchLink><i>NLM ISO Abbreviation: </i>Front Immunol <i>Subsets: </i>MEDLINE
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        Value: 10.3389/fimmu.2026.1761769
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      – Code: eng
        Text: English
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      – TitleFull: Double negative T cells (CD4-/CD8-) are associated with Trypanosoma cruzi persistence in the mouse colon during chronic Chagas disease.
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              Text: 2026 Mar 18
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