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miR-100-5p Enhances Cell Cycle-Mediated Chemoresistance by Modulating the CTDSPL/pRB/E2F1 Signaling Pathway in Oxaliplatin-Resistant Colorectal Cancer Cells.

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Title: miR-100-5p Enhances Cell Cycle-Mediated Chemoresistance by Modulating the CTDSPL/pRB/E2F1 Signaling Pathway in Oxaliplatin-Resistant Colorectal Cancer Cells.
Authors: Chen YP; School of Medicine, National Defense Medical University, Taipei, Taiwan.; Department of Orthopedic Surgery, Tri-Service General Hospital, Taipei, Taiwan.; Department of Orthopedics, Taichung Armed Forces General Hospital, Taichung, Taiwan., Baskaran R; Cardiovascular and Mitochondrial Related Disease Research Center, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien, Taiwan., Devi HS; Cardiovascular and Mitochondrial Related Disease Research Center, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien, Taiwan., Singh CH; Cardiovascular and Mitochondrial Related Disease Research Center, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien, Taiwan., Lin YJ; Cardiovascular and Mitochondrial Related Disease Research Center, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien, Taiwan.; Department of Research, Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, New Taipei, Taiwan., Shibu MA; Department of Biotechnology, Bharathiar University, Coimbatore, India., Kuo WW; Department of Biological Science and Technology, China Medical University, Taichung, Taiwan., Liao SC; Graduate Institute of Chinese Medical Science, China Medical University, 91 Hsueh-Shih Road, Taichung, Taiwan., Chen MC; Department of Surgery, Division of Colorectal Surgery, Taichung Veterans General Hospital, Taichung, Taiwan., Wang TF; Department of Hematology and Oncology, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien, Taiwan., Li CC; International Medical Center, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien, Taiwan., Ho TJ; Department of Chinese Medicine, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Tzu Chi University, Hualien, Taiwan., Shih TC; Department of Biomedical Imaging and Radiological Science, China Medical University, Taichung, Taiwan., Lin SZ; Buddhist Tzu Chi Foundation Hospital, Hualien, Taiwan.; Bioinnovation Center, Buddhist Tzu Chi Medical Foundation, Hualien, Taiwan.; Department of Neurosurgery, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien, Taiwan., Huang CY; Cardiovascular and Mitochondrial Related Disease Research Center, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien, Taiwan.; Graduate Institute of Biomedical Sciences, China Medical University, Taichung, Taiwan.; Department of Medical Laboratory Science and Biotechnology, Asia University, Taichung, Taiwan.; Department of Medical Research, China Medical University Hospital, China Medical University, Taichung, Taiwan.
Source: Oncology research [Oncol Res] 2026 Mar 23; Vol. 34 (4), pp. 17. Date of Electronic Publication: 2026 Mar 23 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Tech Science Press Country of Publication: United States NLM ID: 9208097 Publication Model: eCollection Cited Medium: Internet ISSN: 1555-3906 (Electronic) Linking ISSN: 09650407 NLM ISO Abbreviation: Oncol Res Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: miR-100-5p Enhances Cell Cycle-Mediated Chemoresistance by Modulating the CTDSPL/pRB/E2F1 Signaling Pathway in Oxaliplatin-Resistant Colorectal Cancer Cells.
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  Data: <searchLink fieldCode="AU" term="%22Chen+YP%22">Chen YP</searchLink>; School of Medicine, National Defense Medical University, Taipei, Taiwan.; Department of Orthopedic Surgery, Tri-Service General Hospital, Taipei, Taiwan.; Department of Orthopedics, Taichung Armed Forces General Hospital, Taichung, Taiwan.<br /><searchLink fieldCode="AU" term="%22Baskaran+R%22">Baskaran R</searchLink>; Cardiovascular and Mitochondrial Related Disease Research Center, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien, Taiwan.<br /><searchLink fieldCode="AU" term="%22Devi+HS%22">Devi HS</searchLink>; Cardiovascular and Mitochondrial Related Disease Research Center, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien, Taiwan.<br /><searchLink fieldCode="AU" term="%22Singh+CH%22">Singh CH</searchLink>; Cardiovascular and Mitochondrial Related Disease Research Center, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien, Taiwan.<br /><searchLink fieldCode="AU" term="%22Lin+YJ%22">Lin YJ</searchLink>; Cardiovascular and Mitochondrial Related Disease Research Center, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien, Taiwan.; Department of Research, Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, New Taipei, Taiwan.<br /><searchLink fieldCode="AU" term="%22Shibu+MA%22">Shibu MA</searchLink>; Department of Biotechnology, Bharathiar University, Coimbatore, India.<br /><searchLink fieldCode="AU" term="%22Kuo+WW%22">Kuo WW</searchLink>; Department of Biological Science and Technology, China Medical University, Taichung, Taiwan.<br /><searchLink fieldCode="AU" term="%22Liao+SC%22">Liao SC</searchLink>; Graduate Institute of Chinese Medical Science, China Medical University, 91 Hsueh-Shih Road, Taichung, Taiwan.<br /><searchLink fieldCode="AU" term="%22Chen+MC%22">Chen MC</searchLink>; Department of Surgery, Division of Colorectal Surgery, Taichung Veterans General Hospital, Taichung, Taiwan.<br /><searchLink fieldCode="AU" term="%22Wang+TF%22">Wang TF</searchLink>; Department of Hematology and Oncology, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien, Taiwan.<br /><searchLink fieldCode="AU" term="%22Li+CC%22">Li CC</searchLink>; International Medical Center, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien, Taiwan.<br /><searchLink fieldCode="AU" term="%22Ho+TJ%22">Ho TJ</searchLink>; Department of Chinese Medicine, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Tzu Chi University, Hualien, Taiwan.<br /><searchLink fieldCode="AU" term="%22Shih+TC%22">Shih TC</searchLink>; Department of Biomedical Imaging and Radiological Science, China Medical University, Taichung, Taiwan.<br /><searchLink fieldCode="AU" term="%22Lin+SZ%22">Lin SZ</searchLink>; Buddhist Tzu Chi Foundation Hospital, Hualien, Taiwan.; Bioinnovation Center, Buddhist Tzu Chi Medical Foundation, Hualien, Taiwan.; Department of Neurosurgery, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien, Taiwan.<br /><searchLink fieldCode="AU" term="%22Huang+CY%22">Huang CY</searchLink>; Cardiovascular and Mitochondrial Related Disease Research Center, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien, Taiwan.; Graduate Institute of Biomedical Sciences, China Medical University, Taichung, Taiwan.; Department of Medical Laboratory Science and Biotechnology, Asia University, Taichung, Taiwan.; Department of Medical Research, China Medical University Hospital, China Medical University, Taichung, Taiwan.
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  Data: <searchLink fieldCode="JN" term="%229208097%22">Oncology research</searchLink> [Oncol Res] 2026 Mar 23; Vol. 34 (4), pp. 17. <i>Date of Electronic Publication: </i>2026 Mar 23 (<i>Print Publication: </i>2026).
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Tech+Science+Press%22">Tech Science Press </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>9208097 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Internet <i>ISSN: </i>1555-3906 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2209650407%22">09650407 </searchLink><i>NLM ISO Abbreviation: </i>Oncol Res <i>Subsets: </i>MEDLINE
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        Value: 10.32604/or.2026.073080
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      – TitleFull: miR-100-5p Enhances Cell Cycle-Mediated Chemoresistance by Modulating the CTDSPL/pRB/E2F1 Signaling Pathway in Oxaliplatin-Resistant Colorectal Cancer Cells.
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