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Characterizing Heterogeneity in Brain Morphology in Traumatic Brain Injury Using Normative Modeling.

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Title: Characterizing Heterogeneity in Brain Morphology in Traumatic Brain Injury Using Normative Modeling.
Authors: Mitchell J; Department of Neuroscience, School of Translational Medicine, Monash University, Melbourne, Australia., McDonald SJ; Department of Neuroscience, School of Translational Medicine, Monash University, Melbourne, Australia.; Department of Neurology, Alfred Health, The Alfred Hospital, Melbourne, Australia., Law M; Department of Neuroscience, School of Translational Medicine, Monash University, Melbourne, Australia.; Department of Radiology, Alfred Health, The Alfred Centre, Melbourne, Australia.; Department of Electrical and Computer Systems Engineering, Monash University, Clayton, Australia., O'Brien TJ; Department of Neuroscience, School of Translational Medicine, Monash University, Melbourne, Australia.; Department of Neurology, Alfred Health, The Alfred Hospital, Melbourne, Australia., Westlye LT; Department of Psychology, University of Oslo & Center for Precision Psychiatry, Division for Mental Health and Addiction, Oslo University Hospital, Norway., Caeyenberghs K; Cognitive Neuroscience Unit, School of Psychology, Deakin University, Burwood, Australia., Newcombe V; Department of Medicine, University of Cambridge, United Kingdom., Sharp DJ; Department of Brain Sciences, Imperial College London & UK Dementia Research Institute, Care Research & Technology Centre, United Kingdom., Mohamed AZ; Department of Cognitive Sciences, College of Humanities and Social Sciences, United Arab Emirates University, Al Ain, Abu Dhabi., Bigler ED; Departments of Psychiatry and Neurology, University of Utah, Salt Lake City., Amiri H; Neuroscience Research Center, Institute of Neuropharmacology, Kerman University of Medical Sciences, Iran., Irimia A; Leonard Davis School of Gerontology & Departments of Biomedical Engineering and Quantitative & Computational Biology, University of Southern California, Los Angeles., Mondello S; Department of Biomedical and Dental Sciences and Morphofunctional Imaging, University of Messina, Italy., Thomopoulos SI; Imaging Genetics Center, Mark & Mary Stevens Neuroimaging & Informatics Institute, Keck School of Medicine, University of Southern California, Los Angeles., Van Horn JD; Department of Psychology and UVA School of Data Science, University of Virginia, Charlottesville., Tate DF; Department of Neurology, University of Utah School of Medicine, Salt Lake City., Wilde EA; Department of Neurology, University of Utah School of Medicine, Salt Lake City., Håberg AK; Department of Neuromedicine and Movement Sciences, Norwegian University of Science and Technology (NTNU), Trondheim, Norway., Monti MM; Department of Psychology, University of California Los Angeles., Edelstein R; Department of Psychology, University of Virginia, Charlottesville., Adamson MM; Department of Neurosurgery, Stanford School of Medicine, CA.; WOMEN CoE, VA Palo Alto Healthcare System, Palo Alto, CA., Walker WC; Department of Physical Medicine and Rehabilitation, School of Medicine, Virginia Commonwealth University, Richmond., Dams-O'Connor K; Department of Rehabilitation and Human Performance, Icahn School of Medicine at Mount Sinai, New York, NY.; Department of Neurology, Icahn School of Medicine at Mount Sinai, New York, NY.; Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY., Deutscher EM; Cognitive Neuroscience Unit, School of Psychology, Deakin University, Burwood, Australia., Dobryakova E; Center for Traumatic Brain Injury, Kessler Foundation, East Hanover, NJ, United States., Hellstrøm T; Department of Physical Medicine and Rehabilitation, Oslo University Hospital, Norway., Dennis EL; Department of Neurology, University of Utah School of Medicine, Salt Lake City., Thompson PM; Imaging Genetics Center, Mark & Mary Stevens Neuroimaging & Informatics Institute, Keck School of Medicine, University of Southern California, Los Angeles.; Departments of Neurology, Pediatrics, Psychiatry, Radiology, Engineering, and Ophthalmology, USC, Los Angeles, CA., Hillary FG; Department of Psychology, Penn State University, State College, PA., Olsen A; Department of Psychology, Norwegian University of Science and Technology, Trondheim, Norway.; Department of Physical Medicine and Rehabilitation, St. Olav's Hospital, Trondheim University Hospital, Norway., Ponsford JL; Monash-Epworth Rehabilitation Research Centre, School of Psychological Sciences, Faculty of Medicine, Nursing and Health Sciences, Monash University, Clayton, Australia; and., Shultz SR; Department of Neuroscience, School of Translational Medicine, Monash University, Melbourne, Australia.; Centre for Trauma & Mental Health, Vancouver Island University, Nanaimo, British Columbia, Canada., Spitz G; Department of Neuroscience, School of Translational Medicine, Monash University, Melbourne, Australia.; Monash-Epworth Rehabilitation Research Centre, School of Psychological Sciences, Faculty of Medicine, Nursing and Health Sciences, Monash University, Clayton, Australia; and.
Source: Neurology [Neurology] 2026 Apr 28; Vol. 106 (8), pp. e214741. Date of Electronic Publication: 2026 Apr 03.
Publication Type: Journal Article
Journal Info: Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 0401060 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1526-632X (Electronic) Linking ISSN: 00283878 NLM ISO Abbreviation: Neurology Subsets: MEDLINE
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  Data: Characterizing Heterogeneity in Brain Morphology in Traumatic Brain Injury Using Normative Modeling.
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  Data: <searchLink fieldCode="AU" term="%22Mitchell+J%22">Mitchell J</searchLink>; Department of Neuroscience, School of Translational Medicine, Monash University, Melbourne, Australia.<br /><searchLink fieldCode="AU" term="%22McDonald+SJ%22">McDonald SJ</searchLink>; Department of Neuroscience, School of Translational Medicine, Monash University, Melbourne, Australia.; Department of Neurology, Alfred Health, The Alfred Hospital, Melbourne, Australia.<br /><searchLink fieldCode="AU" term="%22Law+M%22">Law M</searchLink>; Department of Neuroscience, School of Translational Medicine, Monash University, Melbourne, Australia.; Department of Radiology, Alfred Health, The Alfred Centre, Melbourne, Australia.; Department of Electrical and Computer Systems Engineering, Monash University, Clayton, Australia.<br /><searchLink fieldCode="AU" term="%22O'Brien+TJ%22">O'Brien TJ</searchLink>; Department of Neuroscience, School of Translational Medicine, Monash University, Melbourne, Australia.; Department of Neurology, Alfred Health, The Alfred Hospital, Melbourne, Australia.<br /><searchLink fieldCode="AU" term="%22Westlye+LT%22">Westlye LT</searchLink>; Department of Psychology, University of Oslo & Center for Precision Psychiatry, Division for Mental Health and Addiction, Oslo University Hospital, Norway.<br /><searchLink fieldCode="AU" term="%22Caeyenberghs+K%22">Caeyenberghs K</searchLink>; Cognitive Neuroscience Unit, School of Psychology, Deakin University, Burwood, Australia.<br /><searchLink fieldCode="AU" term="%22Newcombe+V%22">Newcombe V</searchLink>; Department of Medicine, University of Cambridge, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Sharp+DJ%22">Sharp DJ</searchLink>; Department of Brain Sciences, Imperial College London & UK Dementia Research Institute, Care Research & Technology Centre, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Mohamed+AZ%22">Mohamed AZ</searchLink>; Department of Cognitive Sciences, College of Humanities and Social Sciences, United Arab Emirates University, Al Ain, Abu Dhabi.<br /><searchLink fieldCode="AU" term="%22Bigler+ED%22">Bigler ED</searchLink>; Departments of Psychiatry and Neurology, University of Utah, Salt Lake City.<br /><searchLink fieldCode="AU" term="%22Amiri+H%22">Amiri H</searchLink>; Neuroscience Research Center, Institute of Neuropharmacology, Kerman University of Medical Sciences, Iran.<br /><searchLink fieldCode="AU" term="%22Irimia+A%22">Irimia A</searchLink>; Leonard Davis School of Gerontology & Departments of Biomedical Engineering and Quantitative & Computational Biology, University of Southern California, Los Angeles.<br /><searchLink fieldCode="AU" term="%22Mondello+S%22">Mondello S</searchLink>; Department of Biomedical and Dental Sciences and Morphofunctional Imaging, University of Messina, Italy.<br /><searchLink fieldCode="AU" term="%22Thomopoulos+SI%22">Thomopoulos SI</searchLink>; Imaging Genetics Center, Mark & Mary Stevens Neuroimaging & Informatics Institute, Keck School of Medicine, University of Southern California, Los Angeles.<br /><searchLink fieldCode="AU" term="%22Van+Horn+JD%22">Van Horn JD</searchLink>; Department of Psychology and UVA School of Data Science, University of Virginia, Charlottesville.<br /><searchLink fieldCode="AU" term="%22Tate+DF%22">Tate DF</searchLink>; Department of Neurology, University of Utah School of Medicine, Salt Lake City.<br /><searchLink fieldCode="AU" term="%22Wilde+EA%22">Wilde EA</searchLink>; Department of Neurology, University of Utah School of Medicine, Salt Lake City.<br /><searchLink fieldCode="AU" term="%22Håberg+AK%22">Håberg AK</searchLink>; Department of Neuromedicine and Movement Sciences, Norwegian University of Science and Technology (NTNU), Trondheim, Norway.<br /><searchLink fieldCode="AU" term="%22Monti+MM%22">Monti MM</searchLink>; Department of Psychology, University of California Los Angeles.<br /><searchLink fieldCode="AU" term="%22Edelstein+R%22">Edelstein R</searchLink>; Department of Psychology, University of Virginia, Charlottesville.<br /><searchLink fieldCode="AU" term="%22Adamson+MM%22">Adamson MM</searchLink>; Department of Neurosurgery, Stanford School of Medicine, CA.; WOMEN CoE, VA Palo Alto Healthcare System, Palo Alto, CA.<br /><searchLink fieldCode="AU" term="%22Walker+WC%22">Walker WC</searchLink>; Department of Physical Medicine and Rehabilitation, School of Medicine, Virginia Commonwealth University, Richmond.<br /><searchLink fieldCode="AU" term="%22Dams-O'Connor+K%22">Dams-O'Connor K</searchLink>; Department of Rehabilitation and Human Performance, Icahn School of Medicine at Mount Sinai, New York, NY.; Department of Neurology, Icahn School of Medicine at Mount Sinai, New York, NY.; Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY.<br /><searchLink fieldCode="AU" term="%22Deutscher+EM%22">Deutscher EM</searchLink>; Cognitive Neuroscience Unit, School of Psychology, Deakin University, Burwood, Australia.<br /><searchLink fieldCode="AU" term="%22Dobryakova+E%22">Dobryakova E</searchLink>; Center for Traumatic Brain Injury, Kessler Foundation, East Hanover, NJ, United States.<br /><searchLink fieldCode="AU" term="%22Hellstrøm+T%22">Hellstrøm T</searchLink>; Department of Physical Medicine and Rehabilitation, Oslo University Hospital, Norway.<br /><searchLink fieldCode="AU" term="%22Dennis+EL%22">Dennis EL</searchLink>; Department of Neurology, University of Utah School of Medicine, Salt Lake City.<br /><searchLink fieldCode="AU" term="%22Thompson+PM%22">Thompson PM</searchLink>; Imaging Genetics Center, Mark & Mary Stevens Neuroimaging & Informatics Institute, Keck School of Medicine, University of Southern California, Los Angeles.; Departments of Neurology, Pediatrics, Psychiatry, Radiology, Engineering, and Ophthalmology, USC, Los Angeles, CA.<br /><searchLink fieldCode="AU" term="%22Hillary+FG%22">Hillary FG</searchLink>; Department of Psychology, Penn State University, State College, PA.<br /><searchLink fieldCode="AU" term="%22Olsen+A%22">Olsen A</searchLink>; Department of Psychology, Norwegian University of Science and Technology, Trondheim, Norway.; Department of Physical Medicine and Rehabilitation, St. Olav's Hospital, Trondheim University Hospital, Norway.<br /><searchLink fieldCode="AU" term="%22Ponsford+JL%22">Ponsford JL</searchLink>; Monash-Epworth Rehabilitation Research Centre, School of Psychological Sciences, Faculty of Medicine, Nursing and Health Sciences, Monash University, Clayton, Australia; and.<br /><searchLink fieldCode="AU" term="%22Shultz+SR%22">Shultz SR</searchLink>; Department of Neuroscience, School of Translational Medicine, Monash University, Melbourne, Australia.; Centre for Trauma & Mental Health, Vancouver Island University, Nanaimo, British Columbia, Canada.<br /><searchLink fieldCode="AU" term="%22Spitz+G%22">Spitz G</searchLink>; Department of Neuroscience, School of Translational Medicine, Monash University, Melbourne, Australia.; Monash-Epworth Rehabilitation Research Centre, School of Psychological Sciences, Faculty of Medicine, Nursing and Health Sciences, Monash University, Clayton, Australia; and.
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