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Towards clinical translation of nanomedicines: Formulation scale-up and model systems.

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Title: Towards clinical translation of nanomedicines: Formulation scale-up and model systems.
Authors: Kelly OM; Department of Biomedical Engineering, University of Michigan, Ann Arbor, MI, USA., Hanna AR; Department of Bioengineering, University of Pennsylvania, Philadelphia, PA, USA., Byrne AK; Division of Animal Sciences and the National Swine Testing Center, University of Missouri, Columbia, MO, USA., Green JA; Division of Animal Sciences and the National Swine Testing Center, University of Missouri, Columbia, MO, USA., Perisse IV; Department of Animal, Dairy and Veterinary Sciences, Utah State University, Logan, UT, USA., Wells KD; Division of Animal Sciences and the National Swine Testing Center, University of Missouri, Columbia, MO, USA., Murray SA; The Jackson Laboratory, Bar Harbor, ME, USA., Xu J; National Center of Rabbit Models for Translational Research, University of Michigan Medical School, Ann Arbor, MI, USA., Chen YE; National Center of Rabbit Models for Translational Research, University of Michigan Medical School, Ann Arbor, MI, USA., Polejaeva IA; Department of Animal, Dairy and Veterinary Sciences, Utah State University, Logan, UT, USA., Tarantal AF; Departments of Pediatrics and Cell Biology and Human Anatomy, School of Medicine, and California National Primate Research Center, University of California, Davis, Davis, CA, USA., Issadore D; Department of Bioengineering, University of Pennsylvania, Philadelphia, PA, USA., Piotrowski-Daspit AS; Department of Biomedical Engineering, University of Michigan, Ann Arbor, MI, USA; Department of Internal Medicine-Pulmonary and Critical Care Medicine Division, University of Michigan Medical School, Ann Arbor, MI, USA. Electronic address: asapd@umich.edu.
Source: Advanced drug delivery reviews [Adv Drug Deliv Rev] 2026 Jul; Vol. 234, pp. 115862. Date of Electronic Publication: 2026 Mar 31.
Publication Type: Journal Article; Review
Journal Info: Publisher: Elsevier Science Publishers, B.V Country of Publication: Netherlands NLM ID: 8710523 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-8294 (Electronic) Linking ISSN: 0169409X NLM ISO Abbreviation: Adv Drug Deliv Rev Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Towards clinical translation of nanomedicines: Formulation scale-up and model systems.
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  Data: <searchLink fieldCode="AU" term="%22Kelly+OM%22">Kelly OM</searchLink>; Department of Biomedical Engineering, University of Michigan, Ann Arbor, MI, USA.<br /><searchLink fieldCode="AU" term="%22Hanna+AR%22">Hanna AR</searchLink>; Department of Bioengineering, University of Pennsylvania, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Byrne+AK%22">Byrne AK</searchLink>; Division of Animal Sciences and the National Swine Testing Center, University of Missouri, Columbia, MO, USA.<br /><searchLink fieldCode="AU" term="%22Green+JA%22">Green JA</searchLink>; Division of Animal Sciences and the National Swine Testing Center, University of Missouri, Columbia, MO, USA.<br /><searchLink fieldCode="AU" term="%22Perisse+IV%22">Perisse IV</searchLink>; Department of Animal, Dairy and Veterinary Sciences, Utah State University, Logan, UT, USA.<br /><searchLink fieldCode="AU" term="%22Wells+KD%22">Wells KD</searchLink>; Division of Animal Sciences and the National Swine Testing Center, University of Missouri, Columbia, MO, USA.<br /><searchLink fieldCode="AU" term="%22Murray+SA%22">Murray SA</searchLink>; The Jackson Laboratory, Bar Harbor, ME, USA.<br /><searchLink fieldCode="AU" term="%22Xu+J%22">Xu J</searchLink>; National Center of Rabbit Models for Translational Research, University of Michigan Medical School, Ann Arbor, MI, USA.<br /><searchLink fieldCode="AU" term="%22Chen+YE%22">Chen YE</searchLink>; National Center of Rabbit Models for Translational Research, University of Michigan Medical School, Ann Arbor, MI, USA.<br /><searchLink fieldCode="AU" term="%22Polejaeva+IA%22">Polejaeva IA</searchLink>; Department of Animal, Dairy and Veterinary Sciences, Utah State University, Logan, UT, USA.<br /><searchLink fieldCode="AU" term="%22Tarantal+AF%22">Tarantal AF</searchLink>; Departments of Pediatrics and Cell Biology and Human Anatomy, School of Medicine, and California National Primate Research Center, University of California, Davis, Davis, CA, USA.<br /><searchLink fieldCode="AU" term="%22Issadore+D%22">Issadore D</searchLink>; Department of Bioengineering, University of Pennsylvania, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Piotrowski-Daspit+AS%22">Piotrowski-Daspit AS</searchLink>; Department of Biomedical Engineering, University of Michigan, Ann Arbor, MI, USA; Department of Internal Medicine-Pulmonary and Critical Care Medicine Division, University of Michigan Medical School, Ann Arbor, MI, USA. Electronic address: asapd@umich.edu.
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  Data: <searchLink fieldCode="JN" term="%228710523%22">Advanced drug delivery reviews</searchLink> [Adv Drug Deliv Rev] 2026 Jul; Vol. 234, pp. 115862. <i>Date of Electronic Publication: </i>2026 Mar 31.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier+Science+Publishers%2C+B%2EV%22">Elsevier Science Publishers, B.V </searchLink><i>Country of Publication: </i>Netherlands <i>NLM ID: </i>8710523 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1872-8294 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%220169409X%22">0169409X </searchLink><i>NLM ISO Abbreviation: </i>Adv Drug Deliv Rev <i>Subsets: </i>MEDLINE
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              Text: 2026 Jul
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