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Engineered microglial membrane-coated polydopamine-based nanomedicine for precise treatment of Alzheimer's disease.

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Title: Engineered microglial membrane-coated polydopamine-based nanomedicine for precise treatment of Alzheimer's disease.
Authors: Huang Q; Key Laboratory of Drug-Targeting and Drug Delivery System of the Education Ministry, Key Laboratory of Leather Chemistry and Engineering of the Education Ministry, West China School of Pharmacy, Sichuan University, Chengdu 610041, PR China; Shaanxi Key Laboratory of Chinese Medicine Fundamentals and New Drugs Research, School of Pharmacy, Shaanxi University of Chinese Medicine, Xianyang 712046, Shaanxi, PR China., Lv Y; Key Laboratory of Drug-Targeting and Drug Delivery System of the Education Ministry, Key Laboratory of Leather Chemistry and Engineering of the Education Ministry, West China School of Pharmacy, Sichuan University, Chengdu 610041, PR China., Ye X; Key Laboratory of Drug-Targeting and Drug Delivery System of the Education Ministry, Key Laboratory of Leather Chemistry and Engineering of the Education Ministry, West China School of Pharmacy, Sichuan University, Chengdu 610041, PR China., Xia X; Key Laboratory of Drug-Targeting and Drug Delivery System of the Education Ministry, Key Laboratory of Leather Chemistry and Engineering of the Education Ministry, West China School of Pharmacy, Sichuan University, Chengdu 610041, PR China., Chen Y; Key Laboratory of Drug-Targeting and Drug Delivery System of the Education Ministry, Key Laboratory of Leather Chemistry and Engineering of the Education Ministry, West China School of Pharmacy, Sichuan University, Chengdu 610041, PR China., Wang X; Key Laboratory of Drug-Targeting and Drug Delivery System of the Education Ministry, Key Laboratory of Leather Chemistry and Engineering of the Education Ministry, West China School of Pharmacy, Sichuan University, Chengdu 610041, PR China., Tong F; Key Laboratory of Drug-Targeting and Drug Delivery System of the Education Ministry, Key Laboratory of Leather Chemistry and Engineering of the Education Ministry, West China School of Pharmacy, Sichuan University, Chengdu 610041, PR China., Yang W; Key Laboratory of Drug-Targeting and Drug Delivery System of the Education Ministry, Key Laboratory of Leather Chemistry and Engineering of the Education Ministry, West China School of Pharmacy, Sichuan University, Chengdu 610041, PR China., Bozorov K; Department of Organic Synthesis and Bioorganic Chemistry, Institute of Biochemistry, Samarkand State University, Samarkand 140104, Uzbekistan., Shevtsov M; Laboratory of Biomedical Nanotechnologies, Institute of Cytology of the Russian Academy of Sciences (RAS), 194064 Saint-Petersburg, Russia., Li H; School of Food and Biological Engineering, Chengdu University, Chengdu 610106, China., Gao H; Key Laboratory of Drug-Targeting and Drug Delivery System of the Education Ministry, Key Laboratory of Leather Chemistry and Engineering of the Education Ministry, West China School of Pharmacy, Sichuan University, Chengdu 610041, PR China. Electronic address: gaohuile@scu.edu.cn., Ye B; Key Laboratory of Drug-Targeting and Drug Delivery System of the Education Ministry, Key Laboratory of Leather Chemistry and Engineering of the Education Ministry, West China School of Pharmacy, Sichuan University, Chengdu 610041, PR China; China Medical College of Tibet University, Lasa 850002, PR China. Electronic address: benguiye513@scu.edu.cn.
Source: Journal of controlled release : official journal of the Controlled Release Society [J Control Release] 2026 Jun 10; Vol. 394, pp. 114896. Date of Electronic Publication: 2026 Mar 31.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Science Publishers Country of Publication: Netherlands NLM ID: 8607908 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-4995 (Electronic) Linking ISSN: 01683659 NLM ISO Abbreviation: J Control Release Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Engineered microglial membrane-coated polydopamine-based nanomedicine for precise treatment of Alzheimer's disease.
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  Data: <searchLink fieldCode="AU" term="%22Huang+Q%22">Huang Q</searchLink>; Key Laboratory of Drug-Targeting and Drug Delivery System of the Education Ministry, Key Laboratory of Leather Chemistry and Engineering of the Education Ministry, West China School of Pharmacy, Sichuan University, Chengdu 610041, PR China; Shaanxi Key Laboratory of Chinese Medicine Fundamentals and New Drugs Research, School of Pharmacy, Shaanxi University of Chinese Medicine, Xianyang 712046, Shaanxi, PR China.<br /><searchLink fieldCode="AU" term="%22Lv+Y%22">Lv Y</searchLink>; Key Laboratory of Drug-Targeting and Drug Delivery System of the Education Ministry, Key Laboratory of Leather Chemistry and Engineering of the Education Ministry, West China School of Pharmacy, Sichuan University, Chengdu 610041, PR China.<br /><searchLink fieldCode="AU" term="%22Ye+X%22">Ye X</searchLink>; Key Laboratory of Drug-Targeting and Drug Delivery System of the Education Ministry, Key Laboratory of Leather Chemistry and Engineering of the Education Ministry, West China School of Pharmacy, Sichuan University, Chengdu 610041, PR China.<br /><searchLink fieldCode="AU" term="%22Xia+X%22">Xia X</searchLink>; Key Laboratory of Drug-Targeting and Drug Delivery System of the Education Ministry, Key Laboratory of Leather Chemistry and Engineering of the Education Ministry, West China School of Pharmacy, Sichuan University, Chengdu 610041, PR China.<br /><searchLink fieldCode="AU" term="%22Chen+Y%22">Chen Y</searchLink>; Key Laboratory of Drug-Targeting and Drug Delivery System of the Education Ministry, Key Laboratory of Leather Chemistry and Engineering of the Education Ministry, West China School of Pharmacy, Sichuan University, Chengdu 610041, PR China.<br /><searchLink fieldCode="AU" term="%22Wang+X%22">Wang X</searchLink>; Key Laboratory of Drug-Targeting and Drug Delivery System of the Education Ministry, Key Laboratory of Leather Chemistry and Engineering of the Education Ministry, West China School of Pharmacy, Sichuan University, Chengdu 610041, PR China.<br /><searchLink fieldCode="AU" term="%22Tong+F%22">Tong F</searchLink>; Key Laboratory of Drug-Targeting and Drug Delivery System of the Education Ministry, Key Laboratory of Leather Chemistry and Engineering of the Education Ministry, West China School of Pharmacy, Sichuan University, Chengdu 610041, PR China.<br /><searchLink fieldCode="AU" term="%22Yang+W%22">Yang W</searchLink>; Key Laboratory of Drug-Targeting and Drug Delivery System of the Education Ministry, Key Laboratory of Leather Chemistry and Engineering of the Education Ministry, West China School of Pharmacy, Sichuan University, Chengdu 610041, PR China.<br /><searchLink fieldCode="AU" term="%22Bozorov+K%22">Bozorov K</searchLink>; Department of Organic Synthesis and Bioorganic Chemistry, Institute of Biochemistry, Samarkand State University, Samarkand 140104, Uzbekistan.<br /><searchLink fieldCode="AU" term="%22Shevtsov+M%22">Shevtsov M</searchLink>; Laboratory of Biomedical Nanotechnologies, Institute of Cytology of the Russian Academy of Sciences (RAS), 194064 Saint-Petersburg, Russia.<br /><searchLink fieldCode="AU" term="%22Li+H%22">Li H</searchLink>; School of Food and Biological Engineering, Chengdu University, Chengdu 610106, China.<br /><searchLink fieldCode="AU" term="%22Gao+H%22">Gao H</searchLink>; Key Laboratory of Drug-Targeting and Drug Delivery System of the Education Ministry, Key Laboratory of Leather Chemistry and Engineering of the Education Ministry, West China School of Pharmacy, Sichuan University, Chengdu 610041, PR China. Electronic address: gaohuile@scu.edu.cn.<br /><searchLink fieldCode="AU" term="%22Ye+B%22">Ye B</searchLink>; Key Laboratory of Drug-Targeting and Drug Delivery System of the Education Ministry, Key Laboratory of Leather Chemistry and Engineering of the Education Ministry, West China School of Pharmacy, Sichuan University, Chengdu 610041, PR China; China Medical College of Tibet University, Lasa 850002, PR China. Electronic address: benguiye513@scu.edu.cn.
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        Value: 10.1016/j.jconrel.2026.114896
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      – Code: eng
        Text: English
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        StartPage: 114896
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      – TitleFull: Engineered microglial membrane-coated polydopamine-based nanomedicine for precise treatment of Alzheimer's disease.
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            – D: 10
              M: 06
              Text: 2026 Jun 10
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