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Can nanozymes make the leap to the clinic? Advances, hurdles, and prospects.

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Title: Can nanozymes make the leap to the clinic? Advances, hurdles, and prospects.
Authors: Pandey NK; Department of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA; Biofilm Research Labs, Levy Center for Oral Health, School of Dental Medicine, University of Pennsylvania, Philadelphia, PA, USA; Department of Orthodontics, Pediatric and Community Oral Health, School of Dental Medicine, University of Pennsylvania, Philadelphia, PA, USA., Tran HH; Biofilm Research Labs, Levy Center for Oral Health, School of Dental Medicine, University of Pennsylvania, Philadelphia, PA, USA; Department of Orthodontics, Pediatric and Community Oral Health, School of Dental Medicine, University of Pennsylvania, Philadelphia, PA, USA; Department of Chemical and Biomolecular Engineering, School of Engineering and Applied Science, University of Pennsylvania, Philadelphia, PA, USA., Steager EB; Biofilm Research Labs, Levy Center for Oral Health, School of Dental Medicine, University of Pennsylvania, Philadelphia, PA, USA; Department of Mechanical Engineering and Applied Mechanics, School of Engineering and Applied Sciences, University of Pennsylvania, Philadelphia, PA, USA; Center for Innovation and Precision Dentistry, School of Dental Medicine, School of Engineering and Applied Science, University of Pennsylvania, Philadelphia, PA, USA., Cormode DP; Department of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA; Department of Bioengineering, School of Engineering and Applied Science, University of Pennsylvania, Philadelphia, PA, USA. Electronic address: david.cormode@pennmedicine.upenn.edu., Koo H; Biofilm Research Labs, Levy Center for Oral Health, School of Dental Medicine, University of Pennsylvania, Philadelphia, PA, USA; Department of Orthodontics, Pediatric and Community Oral Health, School of Dental Medicine, University of Pennsylvania, Philadelphia, PA, USA; Center for Innovation and Precision Dentistry, School of Dental Medicine, School of Engineering and Applied Science, University of Pennsylvania, Philadelphia, PA, USA; Department of Bioengineering, School of Engineering and Applied Science, University of Pennsylvania, Philadelphia, PA, USA. Electronic address: koohy@upenn.edu.
Source: Trends in biotechnology [Trends Biotechnol] 2026 Apr 02. Date of Electronic Publication: 2026 Apr 02.
Publication Type: Journal Article; Review
Journal Info: Publisher: Elsevier Science Publishers Country of Publication: England NLM ID: 8310903 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-3096 (Electronic) Linking ISSN: 01677799 NLM ISO Abbreviation: Trends Biotechnol Subsets: MEDLINE
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        Value: 10.1016/j.tibtech.2025.12.028
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