Elevated trimethylamine levels characterize impaired muscle mass response to leucine-enriched protein supplementation in older adults at risk of sarcopenia.
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| Title: | Elevated trimethylamine levels characterize impaired muscle mass response to leucine-enriched protein supplementation in older adults at risk of sarcopenia. |
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| Authors: | Tang HY; Metabolomics Core Laboratory, Healthy Aging Research Center, Chang Gung University, Taoyuan, Taiwan., Lo CJ; Metabolomics Core Laboratory, Healthy Aging Research Center, Chang Gung University, Taoyuan, Taiwan.; Clinical Metabolomics Core Laboratory, Chang Gung Memorial Hospital at Linkou, Taoyuan, Taiwan., Ho HY; Metabolomics Core Laboratory, Healthy Aging Research Center, Chang Gung University, Taoyuan, Taiwan.; Clinical Metabolomics Core Laboratory, Chang Gung Memorial Hospital at Linkou, Taoyuan, Taiwan.; Graduate Institute of Biomedical Sciences, College of Medicine, Chang Gung University, Taoyuan, Taiwan.; Department of Medical Biotechnology and Laboratory Science, College of Medicine, Chang Gung University, Taoyuan, Taiwan.; Research Center for Emerging Viral Infections, Chang Gung University, Taoyuan, Taiwan., Yang CH; Metabolomics Core Laboratory, Healthy Aging Research Center, Chang Gung University, Taoyuan, Taiwan., Chang CY; Graduate Institute of Biomedical Sciences, College of Medicine, Chang Gung University, Taoyuan, Taiwan., Ho YH; Department of Biomedical Sciences, College of Medicine, Chang Gung University, Taoyuan, Taiwan., Fang JT; Division of Critical Care Nephrology, Kidney Institute, Chang Gung Memorial Hospital, Linkou Medical Center, Chang Gung University, Taoyuan, Taiwan.; College of Medicine, Chang Gung University, Taoyuan, Taiwan., Lin CM; College of Medicine, Chang Gung University, Taoyuan, Taiwan.; Division of Internal Medicine, Chang Gung Memorial Hospital at Taipei, Taipei, Taiwan.; Department of Health Management, Chang Gung Health and Culture Village, Taoyuan, Taiwan., Cheng ML; Metabolomics Core Laboratory, Healthy Aging Research Center, Chang Gung University, Taoyuan, Taiwan. chengm@mail.cgu.edu.tw.; Clinical Metabolomics Core Laboratory, Chang Gung Memorial Hospital at Linkou, Taoyuan, Taiwan. chengm@mail.cgu.edu.tw.; Graduate Institute of Biomedical Sciences, College of Medicine, Chang Gung University, Taoyuan, Taiwan. chengm@mail.cgu.edu.tw.; Department of Biomedical Sciences, College of Medicine, Chang Gung University, Taoyuan, Taiwan. chengm@mail.cgu.edu.tw. |
| Source: | Npj aging [NPJ Aging] 2026 Apr 04; Vol. 12 (1). Date of Electronic Publication: 2026 Apr 04. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Springer Nature Country of Publication: England NLM ID: 9918402285106676 Publication Model: Electronic Cited Medium: Internet ISSN: 2731-6068 (Electronic) Linking ISSN: 27316068 NLM ISO Abbreviation: NPJ Aging Subsets: PubMed not MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 41935035 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Elevated trimethylamine levels characterize impaired muscle mass response to leucine-enriched protein supplementation in older adults at risk of sarcopenia. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Tang+HY%22">Tang HY</searchLink>; Metabolomics Core Laboratory, Healthy Aging Research Center, Chang Gung University, Taoyuan, Taiwan.<br /><searchLink fieldCode="AU" term="%22Lo+CJ%22">Lo CJ</searchLink>; Metabolomics Core Laboratory, Healthy Aging Research Center, Chang Gung University, Taoyuan, Taiwan.; Clinical Metabolomics Core Laboratory, Chang Gung Memorial Hospital at Linkou, Taoyuan, Taiwan.<br /><searchLink fieldCode="AU" term="%22Ho+HY%22">Ho HY</searchLink>; Metabolomics Core Laboratory, Healthy Aging Research Center, Chang Gung University, Taoyuan, Taiwan.; Clinical Metabolomics Core Laboratory, Chang Gung Memorial Hospital at Linkou, Taoyuan, Taiwan.; Graduate Institute of Biomedical Sciences, College of Medicine, Chang Gung University, Taoyuan, Taiwan.; Department of Medical Biotechnology and Laboratory Science, College of Medicine, Chang Gung University, Taoyuan, Taiwan.; Research Center for Emerging Viral Infections, Chang Gung University, Taoyuan, Taiwan.<br /><searchLink fieldCode="AU" term="%22Yang+CH%22">Yang CH</searchLink>; Metabolomics Core Laboratory, Healthy Aging Research Center, Chang Gung University, Taoyuan, Taiwan.<br /><searchLink fieldCode="AU" term="%22Chang+CY%22">Chang CY</searchLink>; Graduate Institute of Biomedical Sciences, College of Medicine, Chang Gung University, Taoyuan, Taiwan.<br /><searchLink fieldCode="AU" term="%22Ho+YH%22">Ho YH</searchLink>; Department of Biomedical Sciences, College of Medicine, Chang Gung University, Taoyuan, Taiwan.<br /><searchLink fieldCode="AU" term="%22Fang+JT%22">Fang JT</searchLink>; Division of Critical Care Nephrology, Kidney Institute, Chang Gung Memorial Hospital, Linkou Medical Center, Chang Gung University, Taoyuan, Taiwan.; College of Medicine, Chang Gung University, Taoyuan, Taiwan.<br /><searchLink fieldCode="AU" term="%22Lin+CM%22">Lin CM</searchLink>; College of Medicine, Chang Gung University, Taoyuan, Taiwan.; Division of Internal Medicine, Chang Gung Memorial Hospital at Taipei, Taipei, Taiwan.; Department of Health Management, Chang Gung Health and Culture Village, Taoyuan, Taiwan.<br /><searchLink fieldCode="AU" term="%22Cheng+ML%22">Cheng ML</searchLink>; Metabolomics Core Laboratory, Healthy Aging Research Center, Chang Gung University, Taoyuan, Taiwan. chengm@mail.cgu.edu.tw.; Clinical Metabolomics Core Laboratory, Chang Gung Memorial Hospital at Linkou, Taoyuan, Taiwan. chengm@mail.cgu.edu.tw.; Graduate Institute of Biomedical Sciences, College of Medicine, Chang Gung University, Taoyuan, Taiwan. chengm@mail.cgu.edu.tw.; Department of Biomedical Sciences, College of Medicine, Chang Gung University, Taoyuan, Taiwan. chengm@mail.cgu.edu.tw. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%229918402285106676%22">Npj aging</searchLink> [NPJ Aging] 2026 Apr 04; Vol. 12 (1). <i>Date of Electronic Publication: </i>2026 Apr 04. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Springer+Nature%22">Springer Nature </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>9918402285106676 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2731-6068 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2227316068%22">27316068 </searchLink><i>NLM ISO Abbreviation: </i>NPJ Aging <i>Subsets: </i>PubMed not MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=41935035 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1038/s41514-026-00375-9 Languages: – Code: eng Text: English Titles: – TitleFull: Elevated trimethylamine levels characterize impaired muscle mass response to leucine-enriched protein supplementation in older adults at risk of sarcopenia. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Tang HY – PersonEntity: Name: NameFull: Lo CJ – PersonEntity: Name: NameFull: Ho HY – PersonEntity: Name: NameFull: Yang CH – PersonEntity: Name: NameFull: Chang CY – PersonEntity: Name: NameFull: Ho YH – PersonEntity: Name: NameFull: Fang JT – PersonEntity: Name: NameFull: Lin CM – PersonEntity: Name: NameFull: Cheng ML IsPartOfRelationships: – BibEntity: Dates: – D: 04 M: 04 Text: 2026 Apr 04 Type: published Y: 2026 Identifiers: – Type: issn-electronic Value: 2731-6068 Numbering: – Type: volume Value: 12 – Type: issue Value: 1 Titles: – TitleFull: Npj aging Type: main |
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