Attitudes and Practices Regarding Dosing Interval Extension of Biologics in Severe Asthma: A Nationwide Survey and Real-World Data From the Dutch RAPSODI Registry.

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Title: Attitudes and Practices Regarding Dosing Interval Extension of Biologics in Severe Asthma: A Nationwide Survey and Real-World Data From the Dutch RAPSODI Registry.
Authors: Marijnissen CJM; Department of Biomedical Data Sciences, Leiden University Medical Center, Leiden, The Netherlands. Electronic address: c.j.m.marijnissen@lumc.nl., Sont JK; Department of Biomedical Data Sciences, Leiden University Medical Center, Leiden, The Netherlands., Meulmeester FL; Department of Biomedical Data Sciences, Leiden University Medical Center, Leiden, The Netherlands., Wouters MWJM; Department of Biomedical Data Sciences, Leiden University Medical Center, Leiden, The Netherlands., Braunstahl GJ; Department of Pulmonary Medicine, STZ Centre of Excellence for Asthma, COPD and Respiratory Allergy, Franciscus & Vlietland, Rotterdam, The Netherlands; Department of Pulmonary Medicine, Erasmus Medical Center, Rotterdam, The Netherlands., Aldenkamp AF; Department of Pulmonary Medicine, Catharina Hospital, Eindhoven, The Netherlands., Hashimoto S; Department of Respiratory Medicine, Amsterdam University Medical Center, Amsterdam, The Netherlands., Kroes JA; Department of Clinical Pharmacy and Pharmacology, Frisius Medical Center, Leeuwarden, The Netherlands., van den Akker-van Marle ME; Department of Biomedical Data Sciences, Leiden University Medical Center, Leiden, The Netherlands., Steyerberg EW; Department of Biomedical Data Sciences, Leiden University Medical Center, Leiden, The Netherlands; Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands., van Bodegom-Vos L; Department of Biomedical Data Sciences, Leiden University Medical Center, Leiden, The Netherlands., van Bezouw MJ; Department of Social, Health, and Organizational Psychology, Utrecht University, Utrecht, The Netherlands., Hilvering B; Department of Respiratory Medicine, Amsterdam University Medical Center, Amsterdam, The Netherlands., Weersink EJM; Department of Respiratory Medicine, Amsterdam University Medical Center, Amsterdam, The Netherlands., van der Sar-van der Brugge S; Department of Pulmonary Medicine, Amphia Hospital, Breda, The Netherlands., Fieten KB; Dutch Asthma Center Davos, Davos, Switzerland; Swiss Institute of Allergy and Asthma Research (SIAF), University of Zurich, Zurich, Switzerland., Beukert A; Department of Pulmonary Medicine, Deventer Hospital, Deventer, The Netherlands., Retera JMAM; Department of Pulmonary Medicine, Elisabeth-TweeSteden Hospital, Tilburg, The Netherlands., Oud KTM; Department of Pulmonary Medicine, Hospital Gelderse Vallei, Ede, The Netherlands., van der Meer R; Department of Pulmonology, STZ Centre of Excellence for Asthma, HAGA Hospital, The Hague, The Netherlands., Patberg KW; Department of Pulmonary Medicine, Isala Hospital, Zwolle, The Netherlands., Macken T; Department of Pulmonary Medicine, Jeroen Bosch Hospital, Den Bosch, The Netherlands., de Visser VL; Department of Pulmonary Medicine, Laurentius Hospital, Roermond, The Netherlands., Conemans LH; Department of Pulmonary Medicine, Maastricht University Medical Center+, Maastricht, The Netherlands; NUTRIM Institute of Nutrition and Translational Research in Metabolism, Faculty of Health, Medicine and Life Sciences, Maastricht University, Maastricht, The Netherlands., van Velzen E; Department of Pulmonary Medicine, Meander Medical Center, Amersfoort, The Netherlands., van Veen IH; Department of Pulmonary Medicine, Medisch Spectrum Twente, Enschede, The Netherlands., van Huisstede A; Department of Pulmonary Medicine, Noordwest Hospital, Alkmaar, The Netherlands., Romme EAPM; Department of Pulmonary Medicine, Rijnstate, Arnhem, The Netherlands., Amelink M; Department of Pulmonary Medicine, Spaarne Hospital, Haarlem, The Netherlands., van Ruitenbeek CA; Department of Pulmonary Medicine, Ziekenhuisgroep Twente, Almelo, The Netherlands., Ten Brinke A; Department of Pulmonary Medicine, Frisius Medical Center, Leeuwarden, The Netherlands., Kappen JH; Department of Pulmonology, STZ Centre of Excellence for Asthma, HAGA Hospital, The Hague, The Netherlands; Immunomodulation and Tolerance Group, Allergy and Clinical Immunology, National Heart and Lung Institute, Imperial College London, London, United Kingdom.
Source: The journal of allergy and clinical immunology. In practice [J Allergy Clin Immunol Pract] 2026 Jul; Vol. 14 (7), pp. 1612-1619.e3. Date of Electronic Publication: 2026 Apr 03.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Inc Country of Publication: United States NLM ID: 101597220 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2213-2201 (Electronic) NLM ISO Abbreviation: J Allergy Clin Immunol Pract Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Attitudes and Practices Regarding Dosing Interval Extension of Biologics in Severe Asthma: A Nationwide Survey and Real-World Data From the Dutch RAPSODI Registry.
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  Data: <searchLink fieldCode="AU" term="%22Marijnissen+CJM%22">Marijnissen CJM</searchLink>; Department of Biomedical Data Sciences, Leiden University Medical Center, Leiden, The Netherlands. Electronic address: c.j.m.marijnissen@lumc.nl.<br /><searchLink fieldCode="AU" term="%22Sont+JK%22">Sont JK</searchLink>; Department of Biomedical Data Sciences, Leiden University Medical Center, Leiden, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Meulmeester+FL%22">Meulmeester FL</searchLink>; Department of Biomedical Data Sciences, Leiden University Medical Center, Leiden, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Wouters+MWJM%22">Wouters MWJM</searchLink>; Department of Biomedical Data Sciences, Leiden University Medical Center, Leiden, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Braunstahl+GJ%22">Braunstahl GJ</searchLink>; Department of Pulmonary Medicine, STZ Centre of Excellence for Asthma, COPD and Respiratory Allergy, Franciscus & Vlietland, Rotterdam, The Netherlands; Department of Pulmonary Medicine, Erasmus Medical Center, Rotterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Aldenkamp+AF%22">Aldenkamp AF</searchLink>; Department of Pulmonary Medicine, Catharina Hospital, Eindhoven, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Hashimoto+S%22">Hashimoto S</searchLink>; Department of Respiratory Medicine, Amsterdam University Medical Center, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Kroes+JA%22">Kroes JA</searchLink>; Department of Clinical Pharmacy and Pharmacology, Frisius Medical Center, Leeuwarden, The Netherlands.<br /><searchLink fieldCode="AU" term="%22van+den+Akker-van+Marle+ME%22">van den Akker-van Marle ME</searchLink>; Department of Biomedical Data Sciences, Leiden University Medical Center, Leiden, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Steyerberg+EW%22">Steyerberg EW</searchLink>; Department of Biomedical Data Sciences, Leiden University Medical Center, Leiden, The Netherlands; Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands.<br /><searchLink fieldCode="AU" term="%22van+Bodegom-Vos+L%22">van Bodegom-Vos L</searchLink>; Department of Biomedical Data Sciences, Leiden University Medical Center, Leiden, The Netherlands.<br /><searchLink fieldCode="AU" term="%22van+Bezouw+MJ%22">van Bezouw MJ</searchLink>; Department of Social, Health, and Organizational Psychology, Utrecht University, Utrecht, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Hilvering+B%22">Hilvering B</searchLink>; Department of Respiratory Medicine, Amsterdam University Medical Center, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Weersink+EJM%22">Weersink EJM</searchLink>; Department of Respiratory Medicine, Amsterdam University Medical Center, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22van+der+Sar-van+der+Brugge+S%22">van der Sar-van der Brugge S</searchLink>; Department of Pulmonary Medicine, Amphia Hospital, Breda, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Fieten+KB%22">Fieten KB</searchLink>; Dutch Asthma Center Davos, Davos, Switzerland; Swiss Institute of Allergy and Asthma Research (SIAF), University of Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Beukert+A%22">Beukert A</searchLink>; Department of Pulmonary Medicine, Deventer Hospital, Deventer, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Retera+JMAM%22">Retera JMAM</searchLink>; Department of Pulmonary Medicine, Elisabeth-TweeSteden Hospital, Tilburg, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Oud+KTM%22">Oud KTM</searchLink>; Department of Pulmonary Medicine, Hospital Gelderse Vallei, Ede, The Netherlands.<br /><searchLink fieldCode="AU" term="%22van+der+Meer+R%22">van der Meer R</searchLink>; Department of Pulmonology, STZ Centre of Excellence for Asthma, HAGA Hospital, The Hague, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Patberg+KW%22">Patberg KW</searchLink>; Department of Pulmonary Medicine, Isala Hospital, Zwolle, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Macken+T%22">Macken T</searchLink>; Department of Pulmonary Medicine, Jeroen Bosch Hospital, Den Bosch, The Netherlands.<br /><searchLink fieldCode="AU" term="%22de+Visser+VL%22">de Visser VL</searchLink>; Department of Pulmonary Medicine, Laurentius Hospital, Roermond, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Conemans+LH%22">Conemans LH</searchLink>; Department of Pulmonary Medicine, Maastricht University Medical Center+, Maastricht, The Netherlands; NUTRIM Institute of Nutrition and Translational Research in Metabolism, Faculty of Health, Medicine and Life Sciences, Maastricht University, Maastricht, The Netherlands.<br /><searchLink fieldCode="AU" term="%22van+Velzen+E%22">van Velzen E</searchLink>; Department of Pulmonary Medicine, Meander Medical Center, Amersfoort, The Netherlands.<br /><searchLink fieldCode="AU" term="%22van+Veen+IH%22">van Veen IH</searchLink>; Department of Pulmonary Medicine, Medisch Spectrum Twente, Enschede, The Netherlands.<br /><searchLink fieldCode="AU" term="%22van+Huisstede+A%22">van Huisstede A</searchLink>; Department of Pulmonary Medicine, Noordwest Hospital, Alkmaar, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Romme+EAPM%22">Romme EAPM</searchLink>; Department of Pulmonary Medicine, Rijnstate, Arnhem, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Amelink+M%22">Amelink M</searchLink>; Department of Pulmonary Medicine, Spaarne Hospital, Haarlem, The Netherlands.<br /><searchLink fieldCode="AU" term="%22van+Ruitenbeek+CA%22">van Ruitenbeek CA</searchLink>; Department of Pulmonary Medicine, Ziekenhuisgroep Twente, Almelo, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Ten+Brinke+A%22">Ten Brinke A</searchLink>; Department of Pulmonary Medicine, Frisius Medical Center, Leeuwarden, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Kappen+JH%22">Kappen JH</searchLink>; Department of Pulmonology, STZ Centre of Excellence for Asthma, HAGA Hospital, The Hague, The Netherlands; Immunomodulation and Tolerance Group, Allergy and Clinical Immunology, National Heart and Lung Institute, Imperial College London, London, United Kingdom.
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