Expression of ubiquitin carboxyl-terminal hydrolase isozyme L1 and chromogranin A regulated via histone-modification through Rho/ERK/NFκB signaling in oxaliplatin-resistant colorectal cancer cells.

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Title: Expression of ubiquitin carboxyl-terminal hydrolase isozyme L1 and chromogranin A regulated via histone-modification through Rho/ERK/NFκB signaling in oxaliplatin-resistant colorectal cancer cells.
Authors: Lee KC; Division of Colorectal Surgery, Department of Surgery, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Kaohsiung, Taiwan.; Division of Colorectal Surgery, Department of Surgery, Kaohsiung Municipal Fong Shan Hospital (Under the management of Chang Gung Medical Foundation), Kaohsiung, Taiwan.; Division of Colorectal Surgery, Department of Surgery, Kaohsiung Municipal Ta-Tung Hospital, Kaohsiung, Taiwan., Cheng KC; Division of Colorectal Surgery, Department of Surgery, Kaohsiung Municipal Ta-Tung Hospital, Kaohsiung, Taiwan.; Division of Colorectal Surgery, Department of Surgery, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, Taiwan., Huang CY; Division of Colon and Rectal Surgery, Department of Surgery, Chang Gung Memorial Hospital, Chiayi, Taiwan., Hsieh MC; Division of Colon and Rectal Surgery, Department of Surgery, Chang Gung Memorial Hospital, Chiayi, Taiwan., Tung SY; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Chang Gung Memorial Hospital, Chiayi, Taiwan.; College of Medicine, Chang Gung University, Taoyuan, Taiwan., Hsieh YY; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Chang Gung Memorial Hospital, Chiayi, Taiwan.; College of Medicine, Chang Gung University, Taoyuan, Taiwan., Lee KF; Department of Pathology, Chang Gung Memorial Hospital, Chiayi, Taiwan., Teng CC; Department of Nursing, Division of Basic Medical Sciences, Chang Gung University of Science and Technology, Chiayi, Taiwan.; Research Fellow, Chang Gung Memorial Hospital, Chiayi, Taiwan., Kuo HC; Department of Nursing, Division of Basic Medical Sciences, Chang Gung University of Science and Technology, Chiayi, Taiwan.; Research Fellow, Chang Gung Memorial Hospital, Chiayi, Taiwan.; Center for Drug Research and Development, Chang Gung University of Science and Technology, Taoyuan, Taiwan.; Chronic Diseases and Health Promotion Research Center, Chang Gung University of Science and Technology, Chiayi, Taiwan.
Source: International journal of medical sciences [Int J Med Sci] 2026 Feb 26; Vol. 23 (4), pp. 1264-1277. Date of Electronic Publication: 2026 Feb 26 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Ivyspring International Publisher Country of Publication: Australia NLM ID: 101213954 Publication Model: eCollection Cited Medium: Internet ISSN: 1449-1907 (Electronic) Linking ISSN: 14491907 NLM ISO Abbreviation: Int J Med Sci Subsets: MEDLINE
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  Data: Expression of ubiquitin carboxyl-terminal hydrolase isozyme L1 and chromogranin A regulated via histone-modification through Rho/ERK/NFκB signaling in oxaliplatin-resistant colorectal cancer cells.
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  Data: <searchLink fieldCode="AU" term="%22Lee+KC%22">Lee KC</searchLink>; Division of Colorectal Surgery, Department of Surgery, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Kaohsiung, Taiwan.; Division of Colorectal Surgery, Department of Surgery, Kaohsiung Municipal Fong Shan Hospital (Under the management of Chang Gung Medical Foundation), Kaohsiung, Taiwan.; Division of Colorectal Surgery, Department of Surgery, Kaohsiung Municipal Ta-Tung Hospital, Kaohsiung, Taiwan.<br /><searchLink fieldCode="AU" term="%22Cheng+KC%22">Cheng KC</searchLink>; Division of Colorectal Surgery, Department of Surgery, Kaohsiung Municipal Ta-Tung Hospital, Kaohsiung, Taiwan.; Division of Colorectal Surgery, Department of Surgery, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, Taiwan.<br /><searchLink fieldCode="AU" term="%22Huang+CY%22">Huang CY</searchLink>; Division of Colon and Rectal Surgery, Department of Surgery, Chang Gung Memorial Hospital, Chiayi, Taiwan.<br /><searchLink fieldCode="AU" term="%22Hsieh+MC%22">Hsieh MC</searchLink>; Division of Colon and Rectal Surgery, Department of Surgery, Chang Gung Memorial Hospital, Chiayi, Taiwan.<br /><searchLink fieldCode="AU" term="%22Tung+SY%22">Tung SY</searchLink>; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Chang Gung Memorial Hospital, Chiayi, Taiwan.; College of Medicine, Chang Gung University, Taoyuan, Taiwan.<br /><searchLink fieldCode="AU" term="%22Hsieh+YY%22">Hsieh YY</searchLink>; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Chang Gung Memorial Hospital, Chiayi, Taiwan.; College of Medicine, Chang Gung University, Taoyuan, Taiwan.<br /><searchLink fieldCode="AU" term="%22Lee+KF%22">Lee KF</searchLink>; Department of Pathology, Chang Gung Memorial Hospital, Chiayi, Taiwan.<br /><searchLink fieldCode="AU" term="%22Teng+CC%22">Teng CC</searchLink>; Department of Nursing, Division of Basic Medical Sciences, Chang Gung University of Science and Technology, Chiayi, Taiwan.; Research Fellow, Chang Gung Memorial Hospital, Chiayi, Taiwan.<br /><searchLink fieldCode="AU" term="%22Kuo+HC%22">Kuo HC</searchLink>; Department of Nursing, Division of Basic Medical Sciences, Chang Gung University of Science and Technology, Chiayi, Taiwan.; Research Fellow, Chang Gung Memorial Hospital, Chiayi, Taiwan.; Center for Drug Research and Development, Chang Gung University of Science and Technology, Taoyuan, Taiwan.; Chronic Diseases and Health Promotion Research Center, Chang Gung University of Science and Technology, Chiayi, Taiwan.
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  Data: <searchLink fieldCode="JN" term="%22101213954%22">International journal of medical sciences</searchLink> [Int J Med Sci] 2026 Feb 26; Vol. 23 (4), pp. 1264-1277. <i>Date of Electronic Publication: </i>2026 Feb 26 (<i>Print Publication: </i>2026).
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Ivyspring+International+Publisher%22">Ivyspring International Publisher </searchLink><i>Country of Publication: </i>Australia <i>NLM ID: </i>101213954 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Internet <i>ISSN: </i>1449-1907 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2214491907%22">14491907 </searchLink><i>NLM ISO Abbreviation: </i>Int J Med Sci <i>Subsets: </i>MEDLINE
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        Value: 10.7150/ijms.126460
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      – TitleFull: Expression of ubiquitin carboxyl-terminal hydrolase isozyme L1 and chromogranin A regulated via histone-modification through Rho/ERK/NFκB signaling in oxaliplatin-resistant colorectal cancer cells.
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              Text: 2026 Feb 26
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