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Multimodal NIRS-MRI reveals cortical hypoperfusion, hypoxia, and mitochondrial changes in a mouse model of autoimmune inflammatory diseases.

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Title: Multimodal NIRS-MRI reveals cortical hypoperfusion, hypoxia, and mitochondrial changes in a mouse model of autoimmune inflammatory diseases.
Authors: Hashem M; Department of Radiology, Cumming School of Medicine, University of Calgary, Alberta, Canada.; Hotchkiss Brain Institute, Cumming School of Medicine, University of Calgary, Alberta, Canada.; Experimental Imaging Centre, Cumming School of Medicine, University of Calgary, Alberta, Canada., Palset A; Department of Radiology, Cumming School of Medicine, University of Calgary, Alberta, Canada.; Hotchkiss Brain Institute, Cumming School of Medicine, University of Calgary, Alberta, Canada.; Experimental Imaging Centre, Cumming School of Medicine, University of Calgary, Alberta, Canada., Wu Y; Department of Radiology, Cumming School of Medicine, University of Calgary, Alberta, Canada.; Hotchkiss Brain Institute, Cumming School of Medicine, University of Calgary, Alberta, Canada.; Experimental Imaging Centre, Cumming School of Medicine, University of Calgary, Alberta, Canada., Hamilton AM; Department of Radiology, Cumming School of Medicine, University of Calgary, Alberta, Canada.; Hotchkiss Brain Institute, Cumming School of Medicine, University of Calgary, Alberta, Canada.; Experimental Imaging Centre, Cumming School of Medicine, University of Calgary, Alberta, Canada., Wuerch EC; Hotchkiss Brain Institute, Cumming School of Medicine, University of Calgary, Alberta, Canada.; Department of Clinical Neurosciences, Cumming School of Medicine, University of Calgary, Alberta, Canada., Yong VW; Hotchkiss Brain Institute, Cumming School of Medicine, University of Calgary, Alberta, Canada., Dunn JF; Department of Radiology, Cumming School of Medicine, University of Calgary, Alberta, Canada.; Hotchkiss Brain Institute, Cumming School of Medicine, University of Calgary, Alberta, Canada.; Experimental Imaging Centre, Cumming School of Medicine, University of Calgary, Alberta, Canada.
Source: Imaging neuroscience (Cambridge, Mass.) [Imaging Neurosci (Camb)] 2026 Apr 02; Vol. 4. Date of Electronic Publication: 2026 Apr 02 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: The MIT Press Country of Publication: United States NLM ID: 9918663686606676 Publication Model: eCollection Cited Medium: Internet ISSN: 2837-6056 (Electronic) Linking ISSN: 28376056 NLM ISO Abbreviation: Imaging Neurosci (Camb) Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Multimodal NIRS-MRI reveals cortical hypoperfusion, hypoxia, and mitochondrial changes in a mouse model of autoimmune inflammatory diseases.
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  Data: <searchLink fieldCode="AU" term="%22Hashem+M%22">Hashem M</searchLink>; Department of Radiology, Cumming School of Medicine, University of Calgary, Alberta, Canada.; Hotchkiss Brain Institute, Cumming School of Medicine, University of Calgary, Alberta, Canada.; Experimental Imaging Centre, Cumming School of Medicine, University of Calgary, Alberta, Canada.<br /><searchLink fieldCode="AU" term="%22Palset+A%22">Palset A</searchLink>; Department of Radiology, Cumming School of Medicine, University of Calgary, Alberta, Canada.; Hotchkiss Brain Institute, Cumming School of Medicine, University of Calgary, Alberta, Canada.; Experimental Imaging Centre, Cumming School of Medicine, University of Calgary, Alberta, Canada.<br /><searchLink fieldCode="AU" term="%22Wu+Y%22">Wu Y</searchLink>; Department of Radiology, Cumming School of Medicine, University of Calgary, Alberta, Canada.; Hotchkiss Brain Institute, Cumming School of Medicine, University of Calgary, Alberta, Canada.; Experimental Imaging Centre, Cumming School of Medicine, University of Calgary, Alberta, Canada.<br /><searchLink fieldCode="AU" term="%22Hamilton+AM%22">Hamilton AM</searchLink>; Department of Radiology, Cumming School of Medicine, University of Calgary, Alberta, Canada.; Hotchkiss Brain Institute, Cumming School of Medicine, University of Calgary, Alberta, Canada.; Experimental Imaging Centre, Cumming School of Medicine, University of Calgary, Alberta, Canada.<br /><searchLink fieldCode="AU" term="%22Wuerch+EC%22">Wuerch EC</searchLink>; Hotchkiss Brain Institute, Cumming School of Medicine, University of Calgary, Alberta, Canada.; Department of Clinical Neurosciences, Cumming School of Medicine, University of Calgary, Alberta, Canada.<br /><searchLink fieldCode="AU" term="%22Yong+VW%22">Yong VW</searchLink>; Hotchkiss Brain Institute, Cumming School of Medicine, University of Calgary, Alberta, Canada.<br /><searchLink fieldCode="AU" term="%22Dunn+JF%22">Dunn JF</searchLink>; Department of Radiology, Cumming School of Medicine, University of Calgary, Alberta, Canada.; Hotchkiss Brain Institute, Cumming School of Medicine, University of Calgary, Alberta, Canada.; Experimental Imaging Centre, Cumming School of Medicine, University of Calgary, Alberta, Canada.
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        Value: 10.1162/IMAG.a.1192
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              Text: 2026 Apr 02
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