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Nerve Growth Factor is Sufficient to Cause Multiple Osteoarthritis-Relevant Pathologic Features in Naïve Murine Knee Joints.

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Title: Nerve Growth Factor is Sufficient to Cause Multiple Osteoarthritis-Relevant Pathologic Features in Naïve Murine Knee Joints.
Authors: Obeidat AM; Department of Internal Medicine, Division of Rheumatology, Rush University Medical Center, Chicago, Illinois.; Chicago Center on Musculoskeletal Pain (C-COMP), Chicago, Illinois., Newton MD; Department of Orthopaedic Surgery, University of Michigan, Ann Arbor., Li J; Department of Internal Medicine, Division of Rheumatology, Rush University Medical Center, Chicago, Illinois.; Chicago Center on Musculoskeletal Pain (C-COMP), Chicago, Illinois., Hu B; Department of Medicine, Division of Rheumatology, University of Pennsylvania, Philadelphia.; Translational Musculoskeletal Research Center, Corp. Michael J. Crescenz VA Medical Center, Philadelphia, Pennsylvania., Ishihara S; Department of Internal Medicine, Division of Rheumatology, Rush University Medical Center, Chicago, Illinois.; Chicago Center on Musculoskeletal Pain (C-COMP), Chicago, Illinois., Lammlin L; Department of Orthopaedic Surgery, University of Michigan, Ann Arbor.; Institute for Biomechanics, Department of Health Sciences and Technology, ETH Zürich, Zürich, Switzerland., Junginger LM; Department of Orthopaedic Surgery, University of Michigan, Ann Arbor., Farrell EC; Department of Orthopaedic Surgery, University of Michigan, Ann Arbor., Wang L; Department of Internal Medicine, Division of Rheumatology, Rush University Medical Center, Chicago, Illinois.; Chicago Center on Musculoskeletal Pain (C-COMP), Chicago, Illinois., Ko FC; Chicago Center on Musculoskeletal Pain (C-COMP), Chicago, Illinois.; Department of Anatomy & Cell Biology, Rush University Medical Center, Chicago, Illinois., Miller RJ; Chicago Center on Musculoskeletal Pain (C-COMP), Chicago, Illinois.; Department of Pharmacology, Northwestern University Feinberg School of Medicine, Chicago, Illinois., Scanzello CR; Department of Medicine, Division of Rheumatology, University of Pennsylvania, Philadelphia.; Translational Musculoskeletal Research Center, Corp. Michael J. Crescenz VA Medical Center, Philadelphia, Pennsylvania., Maerz T; Department of Orthopaedic Surgery, University of Michigan, Ann Arbor.; Institute for Biomechanics, Department of Health Sciences and Technology, ETH Zürich, Zürich, Switzerland., Miller RE; Department of Internal Medicine, Division of Rheumatology, Rush University Medical Center, Chicago, Illinois.; Chicago Center on Musculoskeletal Pain (C-COMP), Chicago, Illinois., Malfait AM; Department of Internal Medicine, Division of Rheumatology, Rush University Medical Center, Chicago, Illinois.; Chicago Center on Musculoskeletal Pain (C-COMP), Chicago, Illinois.
Source: Arthritis & rheumatology (Hoboken, N.J.) [Arthritis Rheumatol] 2026 Apr 06. Date of Electronic Publication: 2026 Apr 06.
Publication Type: Journal Article
Journal Info: Publisher: Wiley Country of Publication: United States NLM ID: 101623795 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2326-5205 (Electronic) Linking ISSN: 23265191 NLM ISO Abbreviation: Arthritis Rheumatol Subsets: MEDLINE
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  Data: Nerve Growth Factor is Sufficient to Cause Multiple Osteoarthritis-Relevant Pathologic Features in Naïve Murine Knee Joints.
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  Data: <searchLink fieldCode="AU" term="%22Obeidat+AM%22">Obeidat AM</searchLink>; Department of Internal Medicine, Division of Rheumatology, Rush University Medical Center, Chicago, Illinois.; Chicago Center on Musculoskeletal Pain (C-COMP), Chicago, Illinois.<br /><searchLink fieldCode="AU" term="%22Newton+MD%22">Newton MD</searchLink>; Department of Orthopaedic Surgery, University of Michigan, Ann Arbor.<br /><searchLink fieldCode="AU" term="%22Li+J%22">Li J</searchLink>; Department of Internal Medicine, Division of Rheumatology, Rush University Medical Center, Chicago, Illinois.; Chicago Center on Musculoskeletal Pain (C-COMP), Chicago, Illinois.<br /><searchLink fieldCode="AU" term="%22Hu+B%22">Hu B</searchLink>; Department of Medicine, Division of Rheumatology, University of Pennsylvania, Philadelphia.; Translational Musculoskeletal Research Center, Corp. Michael J. Crescenz VA Medical Center, Philadelphia, Pennsylvania.<br /><searchLink fieldCode="AU" term="%22Ishihara+S%22">Ishihara S</searchLink>; Department of Internal Medicine, Division of Rheumatology, Rush University Medical Center, Chicago, Illinois.; Chicago Center on Musculoskeletal Pain (C-COMP), Chicago, Illinois.<br /><searchLink fieldCode="AU" term="%22Lammlin+L%22">Lammlin L</searchLink>; Department of Orthopaedic Surgery, University of Michigan, Ann Arbor.; Institute for Biomechanics, Department of Health Sciences and Technology, ETH Zürich, Zürich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Junginger+LM%22">Junginger LM</searchLink>; Department of Orthopaedic Surgery, University of Michigan, Ann Arbor.<br /><searchLink fieldCode="AU" term="%22Farrell+EC%22">Farrell EC</searchLink>; Department of Orthopaedic Surgery, University of Michigan, Ann Arbor.<br /><searchLink fieldCode="AU" term="%22Wang+L%22">Wang L</searchLink>; Department of Internal Medicine, Division of Rheumatology, Rush University Medical Center, Chicago, Illinois.; Chicago Center on Musculoskeletal Pain (C-COMP), Chicago, Illinois.<br /><searchLink fieldCode="AU" term="%22Ko+FC%22">Ko FC</searchLink>; Chicago Center on Musculoskeletal Pain (C-COMP), Chicago, Illinois.; Department of Anatomy & Cell Biology, Rush University Medical Center, Chicago, Illinois.<br /><searchLink fieldCode="AU" term="%22Miller+RJ%22">Miller RJ</searchLink>; Chicago Center on Musculoskeletal Pain (C-COMP), Chicago, Illinois.; Department of Pharmacology, Northwestern University Feinberg School of Medicine, Chicago, Illinois.<br /><searchLink fieldCode="AU" term="%22Scanzello+CR%22">Scanzello CR</searchLink>; Department of Medicine, Division of Rheumatology, University of Pennsylvania, Philadelphia.; Translational Musculoskeletal Research Center, Corp. Michael J. Crescenz VA Medical Center, Philadelphia, Pennsylvania.<br /><searchLink fieldCode="AU" term="%22Maerz+T%22">Maerz T</searchLink>; Department of Orthopaedic Surgery, University of Michigan, Ann Arbor.; Institute for Biomechanics, Department of Health Sciences and Technology, ETH Zürich, Zürich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Miller+RE%22">Miller RE</searchLink>; Department of Internal Medicine, Division of Rheumatology, Rush University Medical Center, Chicago, Illinois.; Chicago Center on Musculoskeletal Pain (C-COMP), Chicago, Illinois.<br /><searchLink fieldCode="AU" term="%22Malfait+AM%22">Malfait AM</searchLink>; Department of Internal Medicine, Division of Rheumatology, Rush University Medical Center, Chicago, Illinois.; Chicago Center on Musculoskeletal Pain (C-COMP), Chicago, Illinois.
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              Text: 2026 Apr 06
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