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Q1020R in the spike proteins of MERS-CoV from Arabian camels confers resistance against soluble human DPP4.

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Title: Q1020R in the spike proteins of MERS-CoV from Arabian camels confers resistance against soluble human DPP4.
Authors: Chen N; German Primate Center - Leibniz Institute for Primate Research, Göttingen, Germany.; Faculty of Biology and Psychology, Georg-August University Göttingen, Göttingen, Germany.; Institute of Molecular Virology, Ulm University Medical Center, Ulm, Germany., Kleine-Weber H; German Primate Center - Leibniz Institute for Primate Research, Göttingen, Germany.; Faculty of Biology and Psychology, Georg-August University Göttingen, Göttingen, Germany., Alkharsah K; Department of Microbiology, College of Medicine, Imam Abdulrahman Bin Faisal University (IAU), Dammam, Saudi Arabia., Winkler M; German Primate Center - Leibniz Institute for Primate Research, Göttingen, Germany., Volz A; Institute of Virology, University of Veterinary Medicine Hannover, Hanover, Germany.; German Center for Infection Research, Partner Site Hannover-Braunschweig, Hannover, Germany., Müller MA; Institute of Virology, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany.; German Centre for Infection Research (Deutsches Zentrum für Infektionsforschung), Partner site Charité, Berlin, Germany., Corman VM; Institute of Virology, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany.; German Centre for Infection Research (Deutsches Zentrum für Infektionsforschung), Partner site Charité, Berlin, Germany.; Labor Berlin-Charité Vivantes GmbH, Berlin, Germany., Drosten C; Institute of Virology, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany.; German Centre for Infection Research (Deutsches Zentrum für Infektionsforschung), Partner site Charité, Berlin, Germany., Hoffmann M; German Primate Center - Leibniz Institute for Primate Research, Göttingen, Germany., Pöhlmann S; German Primate Center - Leibniz Institute for Primate Research, Göttingen, Germany.; Faculty of Biology and Psychology, Georg-August University Göttingen, Göttingen, Germany.; German Center for Infection Research (DZIF), associated partner site Göttingen, Göttingen, Germany.
Source: Journal of virology [J Virol] 2026 May 19; Vol. 100 (5), pp. e0028226. Date of Electronic Publication: 2026 Apr 06.
Publication Type: Journal Article
Journal Info: Publisher: American Society For Microbiology Country of Publication: United States NLM ID: 0113724 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1098-5514 (Electronic) Linking ISSN: 0022538X NLM ISO Abbreviation: J Virol Subsets: MEDLINE
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  Data: Q1020R in the spike proteins of MERS-CoV from Arabian camels confers resistance against soluble human DPP4.
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  Data: <searchLink fieldCode="AU" term="%22Chen+N%22">Chen N</searchLink>; German Primate Center - Leibniz Institute for Primate Research, Göttingen, Germany.; Faculty of Biology and Psychology, Georg-August University Göttingen, Göttingen, Germany.; Institute of Molecular Virology, Ulm University Medical Center, Ulm, Germany.<br /><searchLink fieldCode="AU" term="%22Kleine-Weber+H%22">Kleine-Weber H</searchLink>; German Primate Center - Leibniz Institute for Primate Research, Göttingen, Germany.; Faculty of Biology and Psychology, Georg-August University Göttingen, Göttingen, Germany.<br /><searchLink fieldCode="AU" term="%22Alkharsah+K%22">Alkharsah K</searchLink>; Department of Microbiology, College of Medicine, Imam Abdulrahman Bin Faisal University (IAU), Dammam, Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22Winkler+M%22">Winkler M</searchLink>; German Primate Center - Leibniz Institute for Primate Research, Göttingen, Germany.<br /><searchLink fieldCode="AU" term="%22Volz+A%22">Volz A</searchLink>; Institute of Virology, University of Veterinary Medicine Hannover, Hanover, Germany.; German Center for Infection Research, Partner Site Hannover-Braunschweig, Hannover, Germany.<br /><searchLink fieldCode="AU" term="%22Müller+MA%22">Müller MA</searchLink>; Institute of Virology, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany.; German Centre for Infection Research (Deutsches Zentrum für Infektionsforschung), Partner site Charité, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Corman+VM%22">Corman VM</searchLink>; Institute of Virology, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany.; German Centre for Infection Research (Deutsches Zentrum für Infektionsforschung), Partner site Charité, Berlin, Germany.; Labor Berlin-Charité Vivantes GmbH, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Drosten+C%22">Drosten C</searchLink>; Institute of Virology, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany.; German Centre for Infection Research (Deutsches Zentrum für Infektionsforschung), Partner site Charité, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Hoffmann+M%22">Hoffmann M</searchLink>; German Primate Center - Leibniz Institute for Primate Research, Göttingen, Germany.<br /><searchLink fieldCode="AU" term="%22Pöhlmann+S%22">Pöhlmann S</searchLink>; German Primate Center - Leibniz Institute for Primate Research, Göttingen, Germany.; Faculty of Biology and Psychology, Georg-August University Göttingen, Göttingen, Germany.; German Center for Infection Research (DZIF), associated partner site Göttingen, Göttingen, Germany.
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              Text: 2026 May 19
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