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Preclinical Activity of the B7-H3-Targeting Antibody-Drug Conjugate Vobramitamab Duocarmazine in Pediatric Solid Tumors.

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Title: Preclinical Activity of the B7-H3-Targeting Antibody-Drug Conjugate Vobramitamab Duocarmazine in Pediatric Solid Tumors.
Authors: Favours E; Greehey Children's Cancer Research Institute, UT Health Science Center at San Antonio, San Antonio, Texas., Tang H; Greehey Children's Cancer Research Institute, UT Health Science Center at San Antonio, San Antonio, Texas., Wong P; Greehey Children's Cancer Research Institute, UT Health Science Center at San Antonio, San Antonio, Texas., Ghilu S; Greehey Children's Cancer Research Institute, UT Health Science Center at San Antonio, San Antonio, Texas., Del Pozo V; Greehey Children's Cancer Research Institute, UT Health Science Center at San Antonio, San Antonio, Texas., Mironova E; Greehey Children's Cancer Research Institute, UT Health Science Center at San Antonio, San Antonio, Texas., Chen Y; Greehey Children's Cancer Research Institute, UT Health Science Center at San Antonio, San Antonio, Texas.; Department of Population Health Sciences, UT Health Science Center at San Antonio, San Antonio, Texas., Stearns T; The Jackson Laboratory , Bar Harbor, Maine., Neuhauser S; The Jackson Laboratory , Bar Harbor, Maine., Earley EJ; RTI International , Research Triangle Park, North Carolina., Erickson SW; RTI International , Research Triangle Park, North Carolina., Kwon JY; The Jackson Laboratory , Bar Harbor, Maine., Jocoy EL; The Jackson Laboratory , Bar Harbor, Maine., Groff D; Division of Oncology and Center for Childhood Cancer Research, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania., Krytska K; Division of Oncology and Center for Childhood Cancer Research, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania., Tsang M; Division of Oncology and Center for Childhood Cancer Research, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania., Teicher BA; National Cancer Institute , Bethesda, Maryland., Mossé YP; Division of Oncology and Center for Childhood Cancer Research, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania., Kolb EA; A.I. duPont Hospital for Children, Wilmington, Delaware., Hav M; MacroGenics (United States) , Rockville, Maryland., Loo D; MacroGenics (United States) , Rockville, Maryland., Houghton PJ; Greehey Children's Cancer Research Institute, UT Health Science Center at San Antonio, San Antonio, Texas., Bult CJ; The Jackson Laboratory , Bar Harbor, Maine., Gorlick RG; Department of Pediatrics, MD Anderson, Houston, Texas., Maris JM; Division of Oncology and Center for Childhood Cancer Research, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania., Smith MA; Cancer Therapy Evaluation Program, National Cancer Institute, Washington, District of Columbia., Kurmasheva RT; Greehey Children's Cancer Research Institute, UT Health Science Center at San Antonio, San Antonio, Texas.; Department of Molecular Medicine, UT Health Science Center at San Antonio, San Antonio, Texas.
Source: Clinical cancer research : an official journal of the American Association for Cancer Research [Clin Cancer Res] 2026 Jul 17; Vol. 32 (14), pp. 3031-3042.
Publication Type: Journal Article
Journal Info: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 9502500 Publication Model: Print Cited Medium: Internet ISSN: 1557-3265 (Electronic) Linking ISSN: 10780432 NLM ISO Abbreviation: Clin Cancer Res Subsets: MEDLINE
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