DPY30 Is an Epigenetic Decoupler Linking Replication Stress to Immunoediting in Pancreatic Cancer.

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Title: DPY30 Is an Epigenetic Decoupler Linking Replication Stress to Immunoediting in Pancreatic Cancer.
Authors: Citron F; Department of Genomic Medicine, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas., Cecchetto L; Department of Genomic Medicine, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas., Granato E; Department of Genomic Medicine, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas., Ho IL; Department of Genomic Medicine, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas., Liu Z; Department of Genomic Medicine, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas., Balestrieri C; Center for Omics Sciences, IRCCS San Raffaele Scientific Institute, Milan, Italy.; Experimental Hematology Unit, IRCCS San Raffaele Scientific Institute, Milan, Italy., Yen EY; Department of Genomic Medicine, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas.; MD Anderson UTHealth Graduate School of Biomedical Sciences, Houston, Texas., Perelli L; Division of Discovery Science, Department of Cancer Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas., Zhang L; Department of Genomic Medicine, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas.; Department of Genitourinary Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas., Castillo Montanez LA; Department of Immunology, The University of Texas MD Anderson Cancer Center, Houston, Texas., Dyke CA; Department of Genomic Medicine, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas., Shah R; Department of Genomic Medicine, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas.; MD Anderson UTHealth Graduate School of Biomedical Sciences, Houston, Texas., Attanasio S; Department of Genomic Medicine, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas., Srinivasan S; TRACTION, The University of Texas MD Anderson Cancer Center, Houston, Texas., Roy S; Division of Discovery Science, Department of Cancer Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas., Kwon HJ; Department of Genomic Medicine, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas.; MD Anderson UTHealth Graduate School of Biomedical Sciences, Houston, Texas., Blazanin N; Department of Genomic Medicine, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas.; Department of Thoracic and Cardiovascular Surgery, The University of Texas MD Anderson Cancer Center, Houston, Texas., Chen Y; Division of Discovery Science, Department of Cancer Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas., Chen KC; Division of Discovery Science, Department of Cancer Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas., Chen Z; Department of Genomic Medicine, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas., Scognamiglio I; Department of Genomic Medicine, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas., Pham N; Department of Genomic Medicine, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas., Jiang S; Department of Genomic Medicine, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas.; TRACTION, The University of Texas MD Anderson Cancer Center, Houston, Texas., Pan J; Department of Immunology, The University of Texas MD Anderson Cancer Center, Houston, Texas., Leung CS; Department of Genomic Medicine, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas., Wang L; Department of Genomic Medicine, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas., Gao S; Department of Genomic Medicine, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas.; TRACTION, The University of Texas MD Anderson Cancer Center, Houston, Texas., Carugo A; TRACTION, The University of Texas MD Anderson Cancer Center, Houston, Texas.; Department of Oncology, IRBM Science Park, Rome, Italy., Wang H; Division of Pathology/Lab Medicine, Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, Texas., Yao W; Department of Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, Texas., Tonon G; Center for Omics Sciences, IRCCS San Raffaele Scientific Institute, Milan, Italy.; Vita-Salute San Raffaele University , Milan, Italy., Bonini MC; Experimental Hematology Unit, IRCCS San Raffaele Scientific Institute, Milan, Italy.; Vita-Salute San Raffaele University , Milan, Italy., Zal MA; Division of VP, Research, Department of Epigenetics and Molecular Carcinogenesis, The University of Texas MD Anderson Cancer Center, Houston, Texas., Jeter C; Division of VP, Research, Department of Epigenetics and Molecular Carcinogenesis, The University of Texas MD Anderson Cancer Center, Houston, Texas., Tainer JA; Division of Discovery Science, Department of Cancer Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas.; Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas., Heffernan TP; TRACTION, The University of Texas MD Anderson Cancer Center, Houston, Texas., Giuliani V; TRACTION, The University of Texas MD Anderson Cancer Center, Houston, Texas., Lissanu Y; Department of Genomic Medicine, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas.; Department of Thoracic and Cardiovascular Surgery, The University of Texas MD Anderson Cancer Center, Houston, Texas., Genovese G; Department of Genomic Medicine, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas.; Department of Genitourinary Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas., Di Pilato M; Department of Immunology, The University of Texas MD Anderson Cancer Center, Houston, Texas., Viale A; Department of Genomic Medicine, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas., Schlacher K; Division of Discovery Science, Department of Cancer Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas., Draetta GF; Department of Genomic Medicine, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas.
Source: Cancer research [Cancer Res] 2026 Jun 15; Vol. 86 (12), pp. 2837-2859.
Publication Type: Journal Article
Journal Info: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 2984705R Publication Model: Print Cited Medium: Internet ISSN: 1538-7445 (Electronic) Linking ISSN: 00085472 NLM ISO Abbreviation: Cancer Res Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1538-7445
DOI:10.1158/0008-5472.CAN-25-3849