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DPY30 Is an Epigenetic Decoupler Linking Replication Stress to Immunoediting in Pancreatic Cancer.

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Title: DPY30 Is an Epigenetic Decoupler Linking Replication Stress to Immunoediting in Pancreatic Cancer.
Authors: Citron F; Department of Genomic Medicine, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas., Cecchetto L; Department of Genomic Medicine, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas., Granato E; Department of Genomic Medicine, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas., Ho IL; Department of Genomic Medicine, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas., Liu Z; Department of Genomic Medicine, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas., Balestrieri C; Center for Omics Sciences, IRCCS San Raffaele Scientific Institute, Milan, Italy.; Experimental Hematology Unit, IRCCS San Raffaele Scientific Institute, Milan, Italy., Yen EY; Department of Genomic Medicine, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas.; MD Anderson UTHealth Graduate School of Biomedical Sciences, Houston, Texas., Perelli L; Division of Discovery Science, Department of Cancer Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas., Zhang L; Department of Genomic Medicine, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas.; Department of Genitourinary Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas., Castillo Montanez LA; Department of Immunology, The University of Texas MD Anderson Cancer Center, Houston, Texas., Dyke CA; Department of Genomic Medicine, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas., Shah R; Department of Genomic Medicine, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas.; MD Anderson UTHealth Graduate School of Biomedical Sciences, Houston, Texas., Attanasio S; Department of Genomic Medicine, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas., Srinivasan S; TRACTION, The University of Texas MD Anderson Cancer Center, Houston, Texas., Roy S; Division of Discovery Science, Department of Cancer Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas., Kwon HJ; Department of Genomic Medicine, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas.; MD Anderson UTHealth Graduate School of Biomedical Sciences, Houston, Texas., Blazanin N; Department of Genomic Medicine, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas.; Department of Thoracic and Cardiovascular Surgery, The University of Texas MD Anderson Cancer Center, Houston, Texas., Chen Y; Division of Discovery Science, Department of Cancer Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas., Chen KC; Division of Discovery Science, Department of Cancer Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas., Chen Z; Department of Genomic Medicine, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas., Scognamiglio I; Department of Genomic Medicine, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas., Pham N; Department of Genomic Medicine, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas., Jiang S; Department of Genomic Medicine, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas.; TRACTION, The University of Texas MD Anderson Cancer Center, Houston, Texas., Pan J; Department of Immunology, The University of Texas MD Anderson Cancer Center, Houston, Texas., Leung CS; Department of Genomic Medicine, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas., Wang L; Department of Genomic Medicine, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas., Gao S; Department of Genomic Medicine, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas.; TRACTION, The University of Texas MD Anderson Cancer Center, Houston, Texas., Carugo A; TRACTION, The University of Texas MD Anderson Cancer Center, Houston, Texas.; Department of Oncology, IRBM Science Park, Rome, Italy., Wang H; Division of Pathology/Lab Medicine, Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, Texas., Yao W; Department of Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, Texas., Tonon G; Center for Omics Sciences, IRCCS San Raffaele Scientific Institute, Milan, Italy.; Vita-Salute San Raffaele University , Milan, Italy., Bonini MC; Experimental Hematology Unit, IRCCS San Raffaele Scientific Institute, Milan, Italy.; Vita-Salute San Raffaele University , Milan, Italy., Zal MA; Division of VP, Research, Department of Epigenetics and Molecular Carcinogenesis, The University of Texas MD Anderson Cancer Center, Houston, Texas., Jeter C; Division of VP, Research, Department of Epigenetics and Molecular Carcinogenesis, The University of Texas MD Anderson Cancer Center, Houston, Texas., Tainer JA; Division of Discovery Science, Department of Cancer Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas.; Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas., Heffernan TP; TRACTION, The University of Texas MD Anderson Cancer Center, Houston, Texas., Giuliani V; TRACTION, The University of Texas MD Anderson Cancer Center, Houston, Texas., Lissanu Y; Department of Genomic Medicine, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas.; Department of Thoracic and Cardiovascular Surgery, The University of Texas MD Anderson Cancer Center, Houston, Texas., Genovese G; Department of Genomic Medicine, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas.; Department of Genitourinary Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas., Di Pilato M; Department of Immunology, The University of Texas MD Anderson Cancer Center, Houston, Texas., Viale A; Department of Genomic Medicine, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas., Schlacher K; Division of Discovery Science, Department of Cancer Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas., Draetta GF; Department of Genomic Medicine, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas.
Source: Cancer research [Cancer Res] 2026 Jun 15; Vol. 86 (12), pp. 2837-2859.
Publication Type: Journal Article
Journal Info: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 2984705R Publication Model: Print Cited Medium: Internet ISSN: 1538-7445 (Electronic) Linking ISSN: 00085472 NLM ISO Abbreviation: Cancer Res Subsets: MEDLINE
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  Data: DPY30 Is an Epigenetic Decoupler Linking Replication Stress to Immunoediting in Pancreatic Cancer.
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  Data: <searchLink fieldCode="AU" term="%22Citron+F%22">Citron F</searchLink>; Department of Genomic Medicine, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas.<br /><searchLink fieldCode="AU" term="%22Cecchetto+L%22">Cecchetto L</searchLink>; Department of Genomic Medicine, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas.<br /><searchLink fieldCode="AU" term="%22Granato+E%22">Granato E</searchLink>; Department of Genomic Medicine, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas.<br /><searchLink fieldCode="AU" term="%22Ho+IL%22">Ho IL</searchLink>; Department of Genomic Medicine, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas.<br /><searchLink fieldCode="AU" term="%22Liu+Z%22">Liu Z</searchLink>; Department of Genomic Medicine, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas.<br /><searchLink fieldCode="AU" term="%22Balestrieri+C%22">Balestrieri C</searchLink>; Center for Omics Sciences, IRCCS San Raffaele Scientific Institute, Milan, Italy.; Experimental Hematology Unit, IRCCS San Raffaele Scientific Institute, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Yen+EY%22">Yen EY</searchLink>; Department of Genomic Medicine, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas.; MD Anderson UTHealth Graduate School of Biomedical Sciences, Houston, Texas.<br /><searchLink fieldCode="AU" term="%22Perelli+L%22">Perelli L</searchLink>; Division of Discovery Science, Department of Cancer Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas.<br /><searchLink fieldCode="AU" term="%22Zhang+L%22">Zhang L</searchLink>; Department of Genomic Medicine, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas.; Department of Genitourinary Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.<br /><searchLink fieldCode="AU" term="%22Castillo+Montanez+LA%22">Castillo Montanez LA</searchLink>; 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Division of Discovery Science, Department of Cancer Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas.<br /><searchLink fieldCode="AU" term="%22Kwon+HJ%22">Kwon HJ</searchLink>; Department of Genomic Medicine, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas.; MD Anderson UTHealth Graduate School of Biomedical Sciences, Houston, Texas.<br /><searchLink fieldCode="AU" term="%22Blazanin+N%22">Blazanin N</searchLink>; Department of Genomic Medicine, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas.; Department of Thoracic and Cardiovascular Surgery, The University of Texas MD Anderson Cancer Center, Houston, Texas.<br /><searchLink fieldCode="AU" term="%22Chen+Y%22">Chen Y</searchLink>; Division of Discovery Science, Department of Cancer Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas.<br /><searchLink fieldCode="AU" term="%22Chen+KC%22">Chen KC</searchLink>; Division of Discovery Science, Department of Cancer Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas.<br /><searchLink fieldCode="AU" term="%22Chen+Z%22">Chen Z</searchLink>; Department of Genomic Medicine, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas.<br /><searchLink fieldCode="AU" term="%22Scognamiglio+I%22">Scognamiglio I</searchLink>; Department of Genomic Medicine, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas.<br /><searchLink fieldCode="AU" term="%22Pham+N%22">Pham N</searchLink>; Department of Genomic Medicine, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas.<br /><searchLink fieldCode="AU" term="%22Jiang+S%22">Jiang S</searchLink>; Department of Genomic Medicine, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas.; TRACTION, The University of Texas MD Anderson Cancer Center, Houston, Texas.<br /><searchLink fieldCode="AU" term="%22Pan+J%22">Pan J</searchLink>; 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Division of Pathology/Lab Medicine, Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, Texas.<br /><searchLink fieldCode="AU" term="%22Yao+W%22">Yao W</searchLink>; Department of Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, Texas.<br /><searchLink fieldCode="AU" term="%22Tonon+G%22">Tonon G</searchLink>; Center for Omics Sciences, IRCCS San Raffaele Scientific Institute, Milan, Italy.; Vita-Salute San Raffaele University , Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Bonini+MC%22">Bonini MC</searchLink>; Experimental Hematology Unit, IRCCS San Raffaele Scientific Institute, Milan, Italy.; Vita-Salute San Raffaele University , Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Zal+MA%22">Zal MA</searchLink>; Division of VP, Research, Department of Epigenetics and Molecular Carcinogenesis, The University of Texas MD Anderson Cancer Center, Houston, Texas.<br /><searchLink fieldCode="AU" term="%22Jeter+C%22">Jeter C</searchLink>; 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Department of Genomic Medicine, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas.; Department of Genitourinary Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.<br /><searchLink fieldCode="AU" term="%22Di+Pilato+M%22">Di Pilato M</searchLink>; Department of Immunology, The University of Texas MD Anderson Cancer Center, Houston, Texas.<br /><searchLink fieldCode="AU" term="%22Viale+A%22">Viale A</searchLink>; Department of Genomic Medicine, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas.<br /><searchLink fieldCode="AU" term="%22Schlacher+K%22">Schlacher K</searchLink>; Division of Discovery Science, Department of Cancer Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas.<br /><searchLink fieldCode="AU" term="%22Draetta+GF%22">Draetta GF</searchLink>; Department of Genomic Medicine, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas.
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