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Anti-inflammatory and antinociceptive effects of fasudil in a reserpine-induced fibromyalgia model: Role of ROCK-regulated leptin-STAT3 signaling.

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Title: Anti-inflammatory and antinociceptive effects of fasudil in a reserpine-induced fibromyalgia model: Role of ROCK-regulated leptin-STAT3 signaling.
Authors: Abdelrheem NM; Postgraduate program in Pharmacology and Toxicology, Faculty of Pharmacy, Cairo University, Egypt; Department of Pharmacology and Toxicology, College of Pharmaceutical Sciences and Drug Manufacturing, Misr University for Science and Technology, 6th of October City, Giza, Egypt., Ahmed MAE; Department of Pharmacology and Toxicology, College of Pharmaceutical Sciences and Drug Manufacturing, Misr University for Science and Technology, 6th of October City, Giza, Egypt., Mohamed AF; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Cairo University, Cairo, 11562, Egypt; Faculty of Pharmacy, King Salman International University (KSIU), South Sinai, 46612, Egypt., El Sayed NS; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Cairo University, Cairo, 11562, Egypt., Shalaby HN; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Cairo University, Cairo, 11562, Egypt. Electronic address: heba.nasr@pharma.cu.edu.eg.
Source: Life sciences [Life Sci] 2026 Jun 15; Vol. 395, pp. 124372. Date of Electronic Publication: 2026 Apr 04.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 0375521 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0631 (Electronic) Linking ISSN: 00243205 NLM ISO Abbreviation: Life Sci Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Abdelrheem+NM%22">Abdelrheem NM</searchLink>; Postgraduate program in Pharmacology and Toxicology, Faculty of Pharmacy, Cairo University, Egypt; Department of Pharmacology and Toxicology, College of Pharmaceutical Sciences and Drug Manufacturing, Misr University for Science and Technology, 6th of October City, Giza, Egypt.<br /><searchLink fieldCode="AU" term="%22Ahmed+MAE%22">Ahmed MAE</searchLink>; Department of Pharmacology and Toxicology, College of Pharmaceutical Sciences and Drug Manufacturing, Misr University for Science and Technology, 6th of October City, Giza, Egypt.<br /><searchLink fieldCode="AU" term="%22Mohamed+AF%22">Mohamed AF</searchLink>; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Cairo University, Cairo, 11562, Egypt; Faculty of Pharmacy, King Salman International University (KSIU), South Sinai, 46612, Egypt.<br /><searchLink fieldCode="AU" term="%22El+Sayed+NS%22">El Sayed NS</searchLink>; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Cairo University, Cairo, 11562, Egypt.<br /><searchLink fieldCode="AU" term="%22Shalaby+HN%22">Shalaby HN</searchLink>; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Cairo University, Cairo, 11562, Egypt. Electronic address: heba.nasr@pharma.cu.edu.eg.
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  Data: <searchLink fieldCode="JN" term="%220375521%22">Life sciences</searchLink> [Life Sci] 2026 Jun 15; Vol. 395, pp. 124372. <i>Date of Electronic Publication: </i>2026 Apr 04.
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        Value: 10.1016/j.lfs.2026.124372
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              Text: 2026 Jun 15
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