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Dual suppression of stemness and redox adaptation in glioblastoma through filaggrin upregulation by an abiraterone-based HDAC inhibitor.

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Title: Dual suppression of stemness and redox adaptation in glioblastoma through filaggrin upregulation by an abiraterone-based HDAC inhibitor.
Authors: Tran HY; School of Pharmacy, College of Pharmacy, Taipei Medical University, Taipei, 110, Taiwan.; Department of Pharmacology and Clinical Pharmacy, Faculty of Pharmacy, Can Tho University of Medicine and Pharmacy, Can Tho City, 900000, Vietnam., Sharma R; School of Pharmacy, College of Pharmacy, Taipei Medical University, Taipei, 110, Taiwan., Lin HY; Taipei Neuroscience Institute, New Taipei City, 235, Taiwan.; Taiwan Brain Disease Foundation, Taipei, 100, Taiwan., Yeh TY; School of Pharmacy, College of Pharmacy, Taipei Medical University, Taipei, 110, Taiwan., Shen CJ; TMU Research Center of Neuroscience, Taipei Medical University, Taipei, 235, Taiwan., Hsu TI; TMU Research Center of Neuroscience, Taipei Medical University, Taipei, 235, Taiwan. dabiemhsu@tmu.edu.tw.; TMU Research Center for Drug Discovery, Taipei Medical University, Taipei, 110, Taiwan. dabiemhsu@tmu.edu.tw.; TMU Research Center of Cancer Translational Medicine, Taipei, 110, Taiwan. dabiemhsu@tmu.edu.tw.; Ph.D. Program in Medical Neuroscience, College of Medical Science and Technology, Taipei Medical University and National Health Research Institutes, Taipei, 235, Taiwan. dabiemhsu@tmu.edu.tw.; International Master Program in Medical Neuroscience, College of Medical Science and Technology, Taipei Medical University, Taipei, 235, Taiwan. dabiemhsu@tmu.edu.tw., Liou JP; School of Pharmacy, College of Pharmacy, Taipei Medical University, Taipei, 110, Taiwan. jpl@tmu.edu.tw.; TMU Research Center for Drug Discovery, Taipei Medical University, Taipei, 110, Taiwan. jpl@tmu.edu.tw.; TMU Research Center of Cancer Translational Medicine, Taipei, 110, Taiwan. jpl@tmu.edu.tw.; Ph.D. Program in Drug Discovery and Development Industry, College of Pharmacy, Taipei Medical University, Taipei, 110, Taiwan. jpl@tmu.edu.tw.
Source: Journal of biomedical science [J Biomed Sci] 2026 Apr 06; Vol. 33 (1). Date of Electronic Publication: 2026 Apr 06.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 9421567 Publication Model: Electronic Cited Medium: Internet ISSN: 1423-0127 (Electronic) Linking ISSN: 10217770 NLM ISO Abbreviation: J Biomed Sci Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Dual suppression of stemness and redox adaptation in glioblastoma through filaggrin upregulation by an abiraterone-based HDAC inhibitor.
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  Data: <searchLink fieldCode="AU" term="%22Tran+HY%22">Tran HY</searchLink>; School of Pharmacy, College of Pharmacy, Taipei Medical University, Taipei, 110, Taiwan.; Department of Pharmacology and Clinical Pharmacy, Faculty of Pharmacy, Can Tho University of Medicine and Pharmacy, Can Tho City, 900000, Vietnam.<br /><searchLink fieldCode="AU" term="%22Sharma+R%22">Sharma R</searchLink>; School of Pharmacy, College of Pharmacy, Taipei Medical University, Taipei, 110, Taiwan.<br /><searchLink fieldCode="AU" term="%22Lin+HY%22">Lin HY</searchLink>; Taipei Neuroscience Institute, New Taipei City, 235, Taiwan.; Taiwan Brain Disease Foundation, Taipei, 100, Taiwan.<br /><searchLink fieldCode="AU" term="%22Yeh+TY%22">Yeh TY</searchLink>; School of Pharmacy, College of Pharmacy, Taipei Medical University, Taipei, 110, Taiwan.<br /><searchLink fieldCode="AU" term="%22Shen+CJ%22">Shen CJ</searchLink>; TMU Research Center of Neuroscience, Taipei Medical University, Taipei, 235, Taiwan.<br /><searchLink fieldCode="AU" term="%22Hsu+TI%22">Hsu TI</searchLink>; TMU Research Center of Neuroscience, Taipei Medical University, Taipei, 235, Taiwan. dabiemhsu@tmu.edu.tw.; TMU Research Center for Drug Discovery, Taipei Medical University, Taipei, 110, Taiwan. dabiemhsu@tmu.edu.tw.; TMU Research Center of Cancer Translational Medicine, Taipei, 110, Taiwan. dabiemhsu@tmu.edu.tw.; Ph.D. Program in Medical Neuroscience, College of Medical Science and Technology, Taipei Medical University and National Health Research Institutes, Taipei, 235, Taiwan. dabiemhsu@tmu.edu.tw.; International Master Program in Medical Neuroscience, College of Medical Science and Technology, Taipei Medical University, Taipei, 235, Taiwan. dabiemhsu@tmu.edu.tw.<br /><searchLink fieldCode="AU" term="%22Liou+JP%22">Liou JP</searchLink>; School of Pharmacy, College of Pharmacy, Taipei Medical University, Taipei, 110, Taiwan. jpl@tmu.edu.tw.; TMU Research Center for Drug Discovery, Taipei Medical University, Taipei, 110, Taiwan. jpl@tmu.edu.tw.; TMU Research Center of Cancer Translational Medicine, Taipei, 110, Taiwan. jpl@tmu.edu.tw.; Ph.D. Program in Drug Discovery and Development Industry, College of Pharmacy, Taipei Medical University, Taipei, 110, Taiwan. jpl@tmu.edu.tw.
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  Data: <searchLink fieldCode="JN" term="%229421567%22">Journal of biomedical science</searchLink> [J Biomed Sci] 2026 Apr 06; Vol. 33 (1). <i>Date of Electronic Publication: </i>2026 Apr 06.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22BioMed+Central%22">BioMed Central </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>9421567 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1423-0127 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2210217770%22">10217770 </searchLink><i>NLM ISO Abbreviation: </i>J Biomed Sci <i>Subsets: </i>MEDLINE
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        Value: 10.1186/s12929-026-01241-2
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        Text: English
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      – TitleFull: Dual suppression of stemness and redox adaptation in glioblastoma through filaggrin upregulation by an abiraterone-based HDAC inhibitor.
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            – D: 06
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              Text: 2026 Apr 06
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              Y: 2026
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