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Rational design of amphiphilic pyrrolidinium derivatives: structure-activity correlation and alkyl chain tuning for superior antimicrobial activity.

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Title: Rational design of amphiphilic pyrrolidinium derivatives: structure-activity correlation and alkyl chain tuning for superior antimicrobial activity.
Authors: Vasilieva EA; Arbuzov Institute of Organic and Physical Chemistry, FRC Kazan Scientific Center of RAS, Arbuzov str. 8, 420088, Kazan, Russia. Dashyna111@mail.ru., Kuznetsova DA; Arbuzov Institute of Organic and Physical Chemistry, FRC Kazan Scientific Center of RAS, Arbuzov str. 8, 420088, Kazan, Russia. Dashyna111@mail.ru., Babkin RA; Arbuzov Institute of Organic and Physical Chemistry, FRC Kazan Scientific Center of RAS, Arbuzov str. 8, 420088, Kazan, Russia. Dashyna111@mail.ru.; Kazan National Research Technological University, Karl Marx Str. 68, 420015, Kazan, Russia., Kuznetsov DM; Arbuzov Institute of Organic and Physical Chemistry, FRC Kazan Scientific Center of RAS, Arbuzov str. 8, 420088, Kazan, Russia. Dashyna111@mail.ru., Lubina AP; Arbuzov Institute of Organic and Physical Chemistry, FRC Kazan Scientific Center of RAS, Arbuzov str. 8, 420088, Kazan, Russia. Dashyna111@mail.ru., Voloshina AD; Arbuzov Institute of Organic and Physical Chemistry, FRC Kazan Scientific Center of RAS, Arbuzov str. 8, 420088, Kazan, Russia. Dashyna111@mail.ru., Valeeva DN; Kazan National Research Technological University, Karl Marx Str. 68, 420015, Kazan, Russia., Zakharova LY; Arbuzov Institute of Organic and Physical Chemistry, FRC Kazan Scientific Center of RAS, Arbuzov str. 8, 420088, Kazan, Russia. Dashyna111@mail.ru.; Kazan National Research Technological University, Karl Marx Str. 68, 420015, Kazan, Russia.
Source: Soft matter [Soft Matter] 2026 Apr 29; Vol. 22 (16), pp. 2981-2994. Date of Electronic Publication: 2026 Apr 29.
Publication Type: Journal Article
Journal Info: Publisher: Royal Society of Chemistry Country of Publication: England NLM ID: 101295070 Publication Model: Electronic Cited Medium: Internet ISSN: 1744-6848 (Electronic) Linking ISSN: 1744683X NLM ISO Abbreviation: Soft Matter Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Vasilieva+EA%22">Vasilieva EA</searchLink>; Arbuzov Institute of Organic and Physical Chemistry, FRC Kazan Scientific Center of RAS, Arbuzov str. 8, 420088, Kazan, Russia. Dashyna111@mail.ru.<br /><searchLink fieldCode="AU" term="%22Kuznetsova+DA%22">Kuznetsova DA</searchLink>; Arbuzov Institute of Organic and Physical Chemistry, FRC Kazan Scientific Center of RAS, Arbuzov str. 8, 420088, Kazan, Russia. Dashyna111@mail.ru.<br /><searchLink fieldCode="AU" term="%22Babkin+RA%22">Babkin RA</searchLink>; Arbuzov Institute of Organic and Physical Chemistry, FRC Kazan Scientific Center of RAS, Arbuzov str. 8, 420088, Kazan, Russia. Dashyna111@mail.ru.; Kazan National Research Technological University, Karl Marx Str. 68, 420015, Kazan, Russia.<br /><searchLink fieldCode="AU" term="%22Kuznetsov+DM%22">Kuznetsov DM</searchLink>; Arbuzov Institute of Organic and Physical Chemistry, FRC Kazan Scientific Center of RAS, Arbuzov str. 8, 420088, Kazan, Russia. Dashyna111@mail.ru.<br /><searchLink fieldCode="AU" term="%22Lubina+AP%22">Lubina AP</searchLink>; Arbuzov Institute of Organic and Physical Chemistry, FRC Kazan Scientific Center of RAS, Arbuzov str. 8, 420088, Kazan, Russia. Dashyna111@mail.ru.<br /><searchLink fieldCode="AU" term="%22Voloshina+AD%22">Voloshina AD</searchLink>; Arbuzov Institute of Organic and Physical Chemistry, FRC Kazan Scientific Center of RAS, Arbuzov str. 8, 420088, Kazan, Russia. Dashyna111@mail.ru.<br /><searchLink fieldCode="AU" term="%22Valeeva+DN%22">Valeeva DN</searchLink>; Kazan National Research Technological University, Karl Marx Str. 68, 420015, Kazan, Russia.<br /><searchLink fieldCode="AU" term="%22Zakharova+LY%22">Zakharova LY</searchLink>; Arbuzov Institute of Organic and Physical Chemistry, FRC Kazan Scientific Center of RAS, Arbuzov str. 8, 420088, Kazan, Russia. Dashyna111@mail.ru.; Kazan National Research Technological University, Karl Marx Str. 68, 420015, Kazan, Russia.
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  Data: <searchLink fieldCode="JN" term="%22101295070%22">Soft matter</searchLink> [Soft Matter] 2026 Apr 29; Vol. 22 (16), pp. 2981-2994. <i>Date of Electronic Publication: </i>2026 Apr 29.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Royal+Society+of+Chemistry%22">Royal Society of Chemistry </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101295070 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1744-6848 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%221744683X%22">1744683X </searchLink><i>NLM ISO Abbreviation: </i>Soft Matter <i>Subsets: </i>MEDLINE
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              Text: 2026 Apr 29
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