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How to train your rodent: Recommendations for the preclinical study of exercise-induced benefits in metabolic research.

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Title: How to train your rodent: Recommendations for the preclinical study of exercise-induced benefits in metabolic research.
Authors: Raun SH; Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Pham TCP; Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark; Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, 50931 Cologne, Germany., Viggars MR; Department of Physiology and Aging, University of Florida, Gainesville, FL, USA., Ato S; Faculty of Medical Science, Nippon Sport Science University, Tokyo, Japan., Takagaki Y; Section on Integrative Physiology and Metabolism, Joslin Diabetes Center, Department of Medicine, Harvard Medical School, Boston, MA, USA., Yan Z; Fralin Biomedical Research Institute at Virginia Tech Carilion, Roanoke, VA, USA., De Bock K; Laboratory for Exercise and Health, Department of Health Sciences and Technology (DHEST), Swiss Federal Institute of Technology (ETH Zürich), Zurich, Switzerland., Hornberger TA; Department of Comparative Biosciences, School of Veterinary Medicine, University of Wisconsin-Madison, Madison, WI, USA., Richter EA; Department of Nutrition, Exercise and Sports, Faculty of Science, University of Copenhagen, Copenhagen, Denmark., Auwerx J; Laboratory of Integrative Systems Physiology, École Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland., Goodyear LJ; Section on Integrative Physiology and Metabolism, Joslin Diabetes Center, Department of Medicine, Harvard Medical School, Boston, MA, USA., Febbraio MA; Drug Discovery Biology, Monash Institute of Pharmaceutical Sciences, Monash University, Melbourne, VIC, Australia; Cellular and Molecular Metabolism Laboratory, Baker Heart and Diabetes Institute, Melbourne, VIC, Australia., Esser KA; Department of Physiology and Aging, University of Florida, Gainesville, FL, USA., Sylow L; Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark. Electronic address: lykkesylow@sund.ku.dk.
Source: Cell metabolism [Cell Metab] 2026 Jul 07; Vol. 38 (7), pp. 1273-1296. Date of Electronic Publication: 2026 Apr 06.
Publication Type: Journal Article; Review
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101233170 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1932-7420 (Electronic) Linking ISSN: 15504131 NLM ISO Abbreviation: Cell Metab Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Raun+SH%22">Raun SH</searchLink>; Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Pham+TCP%22">Pham TCP</searchLink>; Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark; Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, 50931 Cologne, Germany.<br /><searchLink fieldCode="AU" term="%22Viggars+MR%22">Viggars MR</searchLink>; Department of Physiology and Aging, University of Florida, Gainesville, FL, USA.<br /><searchLink fieldCode="AU" term="%22Ato+S%22">Ato S</searchLink>; Faculty of Medical Science, Nippon Sport Science University, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Takagaki+Y%22">Takagaki Y</searchLink>; Section on Integrative Physiology and Metabolism, Joslin Diabetes Center, Department of Medicine, Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Yan+Z%22">Yan Z</searchLink>; Fralin Biomedical Research Institute at Virginia Tech Carilion, Roanoke, VA, USA.<br /><searchLink fieldCode="AU" term="%22De+Bock+K%22">De Bock K</searchLink>; Laboratory for Exercise and Health, Department of Health Sciences and Technology (DHEST), Swiss Federal Institute of Technology (ETH Zürich), Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Hornberger+TA%22">Hornberger TA</searchLink>; Department of Comparative Biosciences, School of Veterinary Medicine, University of Wisconsin-Madison, Madison, WI, USA.<br /><searchLink fieldCode="AU" term="%22Richter+EA%22">Richter EA</searchLink>; Department of Nutrition, Exercise and Sports, Faculty of Science, University of Copenhagen, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Auwerx+J%22">Auwerx J</searchLink>; Laboratory of Integrative Systems Physiology, École Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland.<br /><searchLink fieldCode="AU" term="%22Goodyear+LJ%22">Goodyear LJ</searchLink>; Section on Integrative Physiology and Metabolism, Joslin Diabetes Center, Department of Medicine, Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Febbraio+MA%22">Febbraio MA</searchLink>; Drug Discovery Biology, Monash Institute of Pharmaceutical Sciences, Monash University, Melbourne, VIC, Australia; Cellular and Molecular Metabolism Laboratory, Baker Heart and Diabetes Institute, Melbourne, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22Esser+KA%22">Esser KA</searchLink>; Department of Physiology and Aging, University of Florida, Gainesville, FL, USA.<br /><searchLink fieldCode="AU" term="%22Sylow+L%22">Sylow L</searchLink>; Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark. Electronic address: lykkesylow@sund.ku.dk.
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