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Global analysis of cancer cell responses to USP9X inhibition.

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Title: Global analysis of cancer cell responses to USP9X inhibition.
Authors: Schenk P; The Walter and Eliza Hall Institute for Medical Research, Parkville, VIC, Australia.; Department of Medical Biology, University of Melbourne, Parkville, VIC, Australia., Devine SM; The Walter and Eliza Hall Institute for Medical Research, Parkville, VIC, Australia.; Department of Medical Biology, University of Melbourne, Parkville, VIC, Australia., Cobbold SA; The Walter and Eliza Hall Institute for Medical Research, Parkville, VIC, Australia.; Department of Medical Biology, University of Melbourne, Parkville, VIC, Australia., Geoghegan ND; The Walter and Eliza Hall Institute for Medical Research, Parkville, VIC, Australia.; Department of Medical Biology, University of Melbourne, Parkville, VIC, Australia., Kyran EL; The Walter and Eliza Hall Institute for Medical Research, Parkville, VIC, Australia.; Cancer Research UK Cambridge Institute, Cambridge, UK.; School of Clinical Medicine, University of Cambridge, Cambridge, UK., Ang CS; Bio21 Molecular Science and Biotechnology Institute, University of Melbourne, Parkville, VIC, Australia., Alexandrovics JA; The Walter and Eliza Hall Institute for Medical Research, Parkville, VIC, Australia.; Department of Medical Biology, University of Melbourne, Parkville, VIC, Australia., Calleja DJ; The Walter and Eliza Hall Institute for Medical Research, Parkville, VIC, Australia.; Department of Medical Biology, University of Melbourne, Parkville, VIC, Australia., Multari DH; The Walter and Eliza Hall Institute for Medical Research, Parkville, VIC, Australia.; Department of Medical Biology, University of Melbourne, Parkville, VIC, Australia., Vaibhav V; The Walter and Eliza Hall Institute for Medical Research, Parkville, VIC, Australia.; Department of Medical Biology, University of Melbourne, Parkville, VIC, Australia., Lu BGC; The Walter and Eliza Hall Institute for Medical Research, Parkville, VIC, Australia.; Department of Medical Biology, University of Melbourne, Parkville, VIC, Australia., Klemm TA; The Walter and Eliza Hall Institute for Medical Research, Parkville, VIC, Australia.; Department of Medical Biology, University of Melbourne, Parkville, VIC, Australia., Dagley LF; The Walter and Eliza Hall Institute for Medical Research, Parkville, VIC, Australia.; Department of Medical Biology, University of Melbourne, Parkville, VIC, Australia., Lowes KN; The Walter and Eliza Hall Institute for Medical Research, Parkville, VIC, Australia.; Department of Medical Biology, University of Melbourne, Parkville, VIC, Australia., Williamson NA; Bio21 Molecular Science and Biotechnology Institute, University of Melbourne, Parkville, VIC, Australia., Eichhorn PJA; Curtin Medical School, Curtin University, Bentley, WA, Australia.; Curtin Health Innovation Research Institute, Curtin University, Bentley, WA, Australia., Ng AP; The Walter and Eliza Hall Institute for Medical Research, Parkville, VIC, Australia.; Department of Medical Biology, University of Melbourne, Parkville, VIC, Australia.; Clinical Haematology Department, The Royal Melbourne Hospital and Peter MacCallum Cancer Centre, Parkville, VIC, Australia.; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Parkville, VIC, Australia., Feltham R; The Walter and Eliza Hall Institute for Medical Research, Parkville, VIC, Australia.; Department of Medical Biology, University of Melbourne, Parkville, VIC, Australia., Komander D; The Walter and Eliza Hall Institute for Medical Research, Parkville, VIC, Australia. dk@wehi.edu.au.; Department of Medical Biology, University of Melbourne, Parkville, VIC, Australia. dk@wehi.edu.au.
Source: The EMBO journal [EMBO J] 2026 May; Vol. 45 (9), pp. 3306-3331. Date of Electronic Publication: 2026 Apr 07.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8208664 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1460-2075 (Electronic) Linking ISSN: 02614189 NLM ISO Abbreviation: EMBO J Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Schenk+P%22">Schenk P</searchLink>; The Walter and Eliza Hall Institute for Medical Research, Parkville, VIC, Australia.; Department of Medical Biology, University of Melbourne, Parkville, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22Devine+SM%22">Devine SM</searchLink>; The Walter and Eliza Hall Institute for Medical Research, Parkville, VIC, Australia.; Department of Medical Biology, University of Melbourne, Parkville, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22Cobbold+SA%22">Cobbold SA</searchLink>; The Walter and Eliza Hall Institute for Medical Research, Parkville, VIC, Australia.; Department of Medical Biology, University of Melbourne, Parkville, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22Geoghegan+ND%22">Geoghegan ND</searchLink>; The Walter and Eliza Hall Institute for Medical Research, Parkville, VIC, Australia.; Department of Medical Biology, University of Melbourne, Parkville, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22Kyran+EL%22">Kyran EL</searchLink>; The Walter and Eliza Hall Institute for Medical Research, Parkville, VIC, Australia.; Cancer Research UK Cambridge Institute, Cambridge, UK.; School of Clinical Medicine, University of Cambridge, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Ang+CS%22">Ang CS</searchLink>; Bio21 Molecular Science and Biotechnology Institute, University of Melbourne, Parkville, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22Alexandrovics+JA%22">Alexandrovics JA</searchLink>; The Walter and Eliza Hall Institute for Medical Research, Parkville, VIC, Australia.; Department of Medical Biology, University of Melbourne, Parkville, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22Calleja+DJ%22">Calleja DJ</searchLink>; The Walter and Eliza Hall Institute for Medical Research, Parkville, VIC, Australia.; Department of Medical Biology, University of Melbourne, Parkville, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22Multari+DH%22">Multari DH</searchLink>; The Walter and Eliza Hall Institute for Medical Research, Parkville, VIC, Australia.; Department of Medical Biology, University of Melbourne, Parkville, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22Vaibhav+V%22">Vaibhav V</searchLink>; The Walter and Eliza Hall Institute for Medical Research, Parkville, VIC, Australia.; Department of Medical Biology, University of Melbourne, Parkville, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22Lu+BGC%22">Lu BGC</searchLink>; The Walter and Eliza Hall Institute for Medical Research, Parkville, VIC, Australia.; Department of Medical Biology, University of Melbourne, Parkville, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22Klemm+TA%22">Klemm TA</searchLink>; The Walter and Eliza Hall Institute for Medical Research, Parkville, VIC, Australia.; Department of Medical Biology, University of Melbourne, Parkville, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22Dagley+LF%22">Dagley LF</searchLink>; The Walter and Eliza Hall Institute for Medical Research, Parkville, VIC, Australia.; Department of Medical Biology, University of Melbourne, Parkville, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22Lowes+KN%22">Lowes KN</searchLink>; The Walter and Eliza Hall Institute for Medical Research, Parkville, VIC, Australia.; Department of Medical Biology, University of Melbourne, Parkville, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22Williamson+NA%22">Williamson NA</searchLink>; Bio21 Molecular Science and Biotechnology Institute, University of Melbourne, Parkville, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22Eichhorn+PJA%22">Eichhorn PJA</searchLink>; Curtin Medical School, Curtin University, Bentley, WA, Australia.; Curtin Health Innovation Research Institute, Curtin University, Bentley, WA, Australia.<br /><searchLink fieldCode="AU" term="%22Ng+AP%22">Ng AP</searchLink>; The Walter and Eliza Hall Institute for Medical Research, Parkville, VIC, Australia.; Department of Medical Biology, University of Melbourne, Parkville, VIC, Australia.; Clinical Haematology Department, The Royal Melbourne Hospital and Peter MacCallum Cancer Centre, Parkville, VIC, Australia.; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Parkville, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22Feltham+R%22">Feltham R</searchLink>; The Walter and Eliza Hall Institute for Medical Research, Parkville, VIC, Australia.; Department of Medical Biology, University of Melbourne, Parkville, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22Komander+D%22">Komander D</searchLink>; The Walter and Eliza Hall Institute for Medical Research, Parkville, VIC, Australia. dk@wehi.edu.au.; Department of Medical Biology, University of Melbourne, Parkville, VIC, Australia. dk@wehi.edu.au.
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  Data: <searchLink fieldCode="JN" term="%228208664%22">The EMBO journal</searchLink> [EMBO J] 2026 May; Vol. 45 (9), pp. 3306-3331. <i>Date of Electronic Publication: </i>2026 Apr 07.
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