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Fentanyl-induced cortical and cardiopulmonary damage linked to immune response functions and apoptosis-necrosis networks in a multi-omics mouse model.

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Title: Fentanyl-induced cortical and cardiopulmonary damage linked to immune response functions and apoptosis-necrosis networks in a multi-omics mouse model.
Authors: Chakraborty N; Medical Readiness Systems Biology, Center for Military Psychiatry and Neuroscience (CMPN), Walter Reed Army Institute of Research, Silver Spring, MD, United States., Patel M; Medical Readiness Systems Biology, Center for Military Psychiatry and Neuroscience (CMPN), Walter Reed Army Institute of Research, Silver Spring, MD, United States.; Oak Ridge Institute for Science and Education (ORISE), Oak Ridge, TN, United States., Kannan S; Medical Readiness Systems Biology, Center for Military Psychiatry and Neuroscience (CMPN), Walter Reed Army Institute of Research, Silver Spring, MD, United States.; Culmen International, Alexandria, VA, United States., Moyler C; Medical Readiness Systems Biology, Center for Military Psychiatry and Neuroscience (CMPN), Walter Reed Army Institute of Research, Silver Spring, MD, United States.; Oak Ridge Institute for Science and Education (ORISE), Oak Ridge, TN, United States., Dimitrov G; Medical Readiness Systems Biology, Center for Military Psychiatry and Neuroscience (CMPN), Walter Reed Army Institute of Research, Silver Spring, MD, United States.; GDIT, Culmen International, Alexandria, VA, United States., Gautam A; Medical Readiness Systems Biology, Center for Military Psychiatry and Neuroscience (CMPN), Walter Reed Army Institute of Research, Silver Spring, MD, United States., Newman M; Office of the Vice President for Research and Innovation, Virginia Commonwealth University School of Medicine, Richmond, VA, United States., Hendry-Hofer TB; Department of Emergency Medicine, Center for Combat Research, University of Colorado School of Medicine, Aurora, CO, United States., Boyd J; Department of Emergency Medicine, Center for Combat Research, University of Colorado School of Medicine, Aurora, CO, United States.; Department of Pharmaceutical Sciences, University of Colorado Skaggs School of Pharmacy, Aurora, CO, United States., Hammamieh R; Medical Readiness Systems Biology, Center for Military Psychiatry and Neuroscience (CMPN), Walter Reed Army Institute of Research, Silver Spring, MD, United States.
Source: Frontiers in immunology [Front Immunol] 2026 Mar 23; Vol. 17, pp. 1694651. Date of Electronic Publication: 2026 Mar 23 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Chakraborty+N%22">Chakraborty N</searchLink>; Medical Readiness Systems Biology, Center for Military Psychiatry and Neuroscience (CMPN), Walter Reed Army Institute of Research, Silver Spring, MD, United States.<br /><searchLink fieldCode="AU" term="%22Patel+M%22">Patel M</searchLink>; Medical Readiness Systems Biology, Center for Military Psychiatry and Neuroscience (CMPN), Walter Reed Army Institute of Research, Silver Spring, MD, United States.; Oak Ridge Institute for Science and Education (ORISE), Oak Ridge, TN, United States.<br /><searchLink fieldCode="AU" term="%22Kannan+S%22">Kannan S</searchLink>; Medical Readiness Systems Biology, Center for Military Psychiatry and Neuroscience (CMPN), Walter Reed Army Institute of Research, Silver Spring, MD, United States.; Culmen International, Alexandria, VA, United States.<br /><searchLink fieldCode="AU" term="%22Moyler+C%22">Moyler C</searchLink>; Medical Readiness Systems Biology, Center for Military Psychiatry and Neuroscience (CMPN), Walter Reed Army Institute of Research, Silver Spring, MD, United States.; Oak Ridge Institute for Science and Education (ORISE), Oak Ridge, TN, United States.<br /><searchLink fieldCode="AU" term="%22Dimitrov+G%22">Dimitrov G</searchLink>; Medical Readiness Systems Biology, Center for Military Psychiatry and Neuroscience (CMPN), Walter Reed Army Institute of Research, Silver Spring, MD, United States.; GDIT, Culmen International, Alexandria, VA, United States.<br /><searchLink fieldCode="AU" term="%22Gautam+A%22">Gautam A</searchLink>; Medical Readiness Systems Biology, Center for Military Psychiatry and Neuroscience (CMPN), Walter Reed Army Institute of Research, Silver Spring, MD, United States.<br /><searchLink fieldCode="AU" term="%22Newman+M%22">Newman M</searchLink>; Office of the Vice President for Research and Innovation, Virginia Commonwealth University School of Medicine, Richmond, VA, United States.<br /><searchLink fieldCode="AU" term="%22Hendry-Hofer+TB%22">Hendry-Hofer TB</searchLink>; Department of Emergency Medicine, Center for Combat Research, University of Colorado School of Medicine, Aurora, CO, United States.<br /><searchLink fieldCode="AU" term="%22Boyd+J%22">Boyd J</searchLink>; Department of Emergency Medicine, Center for Combat Research, University of Colorado School of Medicine, Aurora, CO, United States.; Department of Pharmaceutical Sciences, University of Colorado Skaggs School of Pharmacy, Aurora, CO, United States.<br /><searchLink fieldCode="AU" term="%22Hammamieh+R%22">Hammamieh R</searchLink>; Medical Readiness Systems Biology, Center for Military Psychiatry and Neuroscience (CMPN), Walter Reed Army Institute of Research, Silver Spring, MD, United States.
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  Data: <searchLink fieldCode="JN" term="%22101560960%22">Frontiers in immunology</searchLink> [Front Immunol] 2026 Mar 23; Vol. 17, pp. 1694651. <i>Date of Electronic Publication: </i>2026 Mar 23 (<i>Print Publication: </i>2026).
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