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A novel G13-RAPGEF2-RAP1 signaling pathway critical for platelet adhesion and aggregation.

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Title: A novel G13-RAPGEF2-RAP1 signaling pathway critical for platelet adhesion and aggregation.
Authors: Paul DS; Department of Biochemistry and Biophysics, The University of North Carolina at Chapel Hill, Chapel Hill, NC.; UNC Blood Research Center, The University of North Carolina at Chapel Hill, Chapel Hill, NC., Rocco DJ; UNC Blood Research Center, The University of North Carolina at Chapel Hill, Chapel Hill, NC.; Department of Cell Biology and Physiology, The University of North Carolina at Chapel Hill, Chapel Hill, NC., Clark EG; Department of Biochemistry and Biophysics, The University of North Carolina at Chapel Hill, Chapel Hill, NC.; UNC Blood Research Center, The University of North Carolina at Chapel Hill, Chapel Hill, NC., Schug WJ; Department of Biochemistry and Biophysics, The University of North Carolina at Chapel Hill, Chapel Hill, NC.; UNC Blood Research Center, The University of North Carolina at Chapel Hill, Chapel Hill, NC., Martyanov AA; Department of Biochemistry and Biophysics, The University of North Carolina at Chapel Hill, Chapel Hill, NC.; UNC Blood Research Center, The University of North Carolina at Chapel Hill, Chapel Hill, NC., Vander Ploeg MR; Department of Biochemistry and Biophysics, The University of North Carolina at Chapel Hill, Chapel Hill, NC.; UNC Blood Research Center, The University of North Carolina at Chapel Hill, Chapel Hill, NC., Jones SR; Department of Biochemistry and Biophysics, The University of North Carolina at Chapel Hill, Chapel Hill, NC.; UNC Blood Research Center, The University of North Carolina at Chapel Hill, Chapel Hill, NC., Lee RH; Department of Biochemistry and Biophysics, The University of North Carolina at Chapel Hill, Chapel Hill, NC.; UNC Blood Research Center, The University of North Carolina at Chapel Hill, Chapel Hill, NC., Mwiza JMN; Department of Physician Assistant Studies, North Carolina Agricultural and Technical State University, Greensboro, NC., Ballard-Kordeliski A; Department of Biochemistry and Biophysics, The University of North Carolina at Chapel Hill, Chapel Hill, NC.; UNC Blood Research Center, The University of North Carolina at Chapel Hill, Chapel Hill, NC., Deger N; Department of Biochemistry and Biophysics, The University of North Carolina at Chapel Hill, Chapel Hill, NC.; UNC Blood Research Center, The University of North Carolina at Chapel Hill, Chapel Hill, NC., Kawano T; UNC Blood Research Center, The University of North Carolina at Chapel Hill, Chapel Hill, NC.; Department of Medicine, The University of North Carolina at Chapel Hill, Chapel Hill, NC., Mackman N; UNC Blood Research Center, The University of North Carolina at Chapel Hill, Chapel Hill, NC.; Department of Medicine, The University of North Carolina at Chapel Hill, Chapel Hill, NC., Bergmeier W; Department of Biochemistry and Biophysics, The University of North Carolina at Chapel Hill, Chapel Hill, NC.; UNC Blood Research Center, The University of North Carolina at Chapel Hill, Chapel Hill, NC.
Source: Blood [Blood] 2026 Jun 18; Vol. 147 (25), pp. 3102-3112.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 7603509 Publication Model: Print Cited Medium: Internet ISSN: 1528-0020 (Electronic) Linking ISSN: 00064971 NLM ISO Abbreviation: Blood Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: A novel G13-RAPGEF2-RAP1 signaling pathway critical for platelet adhesion and aggregation.
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  Data: <searchLink fieldCode="AU" term="%22Paul+DS%22">Paul DS</searchLink>; Department of Biochemistry and Biophysics, The University of North Carolina at Chapel Hill, Chapel Hill, NC.; UNC Blood Research Center, The University of North Carolina at Chapel Hill, Chapel Hill, NC.<br /><searchLink fieldCode="AU" term="%22Rocco+DJ%22">Rocco DJ</searchLink>; UNC Blood Research Center, The University of North Carolina at Chapel Hill, Chapel Hill, NC.; Department of Cell Biology and Physiology, The University of North Carolina at Chapel Hill, Chapel Hill, NC.<br /><searchLink fieldCode="AU" term="%22Clark+EG%22">Clark EG</searchLink>; Department of Biochemistry and Biophysics, The University of North Carolina at Chapel Hill, Chapel Hill, NC.; UNC Blood Research Center, The University of North Carolina at Chapel Hill, Chapel Hill, NC.<br /><searchLink fieldCode="AU" term="%22Schug+WJ%22">Schug WJ</searchLink>; Department of Biochemistry and Biophysics, The University of North Carolina at Chapel Hill, Chapel Hill, NC.; UNC Blood Research Center, The University of North Carolina at Chapel Hill, Chapel Hill, NC.<br /><searchLink fieldCode="AU" term="%22Martyanov+AA%22">Martyanov AA</searchLink>; Department of Biochemistry and Biophysics, The University of North Carolina at Chapel Hill, Chapel Hill, NC.; UNC Blood Research Center, The University of North Carolina at Chapel Hill, Chapel Hill, NC.<br /><searchLink fieldCode="AU" term="%22Vander+Ploeg+MR%22">Vander Ploeg MR</searchLink>; Department of Biochemistry and Biophysics, The University of North Carolina at Chapel Hill, Chapel Hill, NC.; UNC Blood Research Center, The University of North Carolina at Chapel Hill, Chapel Hill, NC.<br /><searchLink fieldCode="AU" term="%22Jones+SR%22">Jones SR</searchLink>; Department of Biochemistry and Biophysics, The University of North Carolina at Chapel Hill, Chapel Hill, NC.; UNC Blood Research Center, The University of North Carolina at Chapel Hill, Chapel Hill, NC.<br /><searchLink fieldCode="AU" term="%22Lee+RH%22">Lee RH</searchLink>; Department of Biochemistry and Biophysics, The University of North Carolina at Chapel Hill, Chapel Hill, NC.; UNC Blood Research Center, The University of North Carolina at Chapel Hill, Chapel Hill, NC.<br /><searchLink fieldCode="AU" term="%22Mwiza+JMN%22">Mwiza JMN</searchLink>; Department of Physician Assistant Studies, North Carolina Agricultural and Technical State University, Greensboro, NC.<br /><searchLink fieldCode="AU" term="%22Ballard-Kordeliski+A%22">Ballard-Kordeliski A</searchLink>; Department of Biochemistry and Biophysics, The University of North Carolina at Chapel Hill, Chapel Hill, NC.; UNC Blood Research Center, The University of North Carolina at Chapel Hill, Chapel Hill, NC.<br /><searchLink fieldCode="AU" term="%22Deger+N%22">Deger N</searchLink>; Department of Biochemistry and Biophysics, The University of North Carolina at Chapel Hill, Chapel Hill, NC.; UNC Blood Research Center, The University of North Carolina at Chapel Hill, Chapel Hill, NC.<br /><searchLink fieldCode="AU" term="%22Kawano+T%22">Kawano T</searchLink>; UNC Blood Research Center, The University of North Carolina at Chapel Hill, Chapel Hill, NC.; Department of Medicine, The University of North Carolina at Chapel Hill, Chapel Hill, NC.<br /><searchLink fieldCode="AU" term="%22Mackman+N%22">Mackman N</searchLink>; UNC Blood Research Center, The University of North Carolina at Chapel Hill, Chapel Hill, NC.; Department of Medicine, The University of North Carolina at Chapel Hill, Chapel Hill, NC.<br /><searchLink fieldCode="AU" term="%22Bergmeier+W%22">Bergmeier W</searchLink>; Department of Biochemistry and Biophysics, The University of North Carolina at Chapel Hill, Chapel Hill, NC.; UNC Blood Research Center, The University of North Carolina at Chapel Hill, Chapel Hill, NC.
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