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The social dimension of apathy: evidence for a distinct domain from 11,243 individuals across health and neurocognitive disorders.

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Title: The social dimension of apathy: evidence for a distinct domain from 11,243 individuals across health and neurocognitive disorders.
Authors: Zhao S; Department of Experimental Psychology, University of Oxford, Oxford, OX1 3EL, UK. sijia.zhao@psy.ox.ac.uk., Ye R; Department of Neurology, The First Affiliated Hospital of Anhui Medical University, Hefei, 230022, China.; School of Mental Health and Psychological Sciences, Anhui Medical University, Hefei, 230032, China.; Anhui Province Key Laboratory of Cognition and Neuropsychiatric Disorders, Hefei, 230022, China.; Collaborative Innovation Center of Neuropsychiatric Disorders and Mental Health, Hefei, 230032, China., Tang QY; Department of Physics, Hong Kong Baptist University, Hong Kong, China., Attaallah B; Department of Brain Sciences, Imperial College London, London, W12 0BZ, UK.; Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, OX3 9DU, UK., Toniolo S; Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, OX3 9DU, UK.; Cognitive Disorders Clinic, John Radcliffe Hospital, Oxford, OX3 9DU, UK., Saleh Y; Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, OX3 9DU, UK.; Cognitive Disorders Clinic, John Radcliffe Hospital, Oxford, OX3 9DU, UK., Rouse MA; MRC Cognition and Brain Sciences Unit, University of Cambridge, Cambridge, CB2 7EF, UK., Garrard P; School of Health and Medical Sciences, City St George's, University of London, London, SW17 0RE, UK., Broulidakis MJ; Department of Experimental Psychology, University of Oxford, Oxford, OX1 3EL, UK.; Cognitive Disorders Clinic, John Radcliffe Hospital, Oxford, OX3 9DU, UK., Thompson S; Cognitive Disorders Clinic, John Radcliffe Hospital, Oxford, OX3 9DU, UK., Manohar SG; Department of Experimental Psychology, University of Oxford, Oxford, OX1 3EL, UK.; Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, OX3 9DU, UK.; Cognitive Disorders Clinic, John Radcliffe Hospital, Oxford, OX3 9DU, UK., Irani SR; Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, OX3 9DU, UK.; Department of Neurology, Mayo Clinic, Jacksonville, FL, 32224, USA.; Department of Neurosciences, Mayo Clinic, Jacksonville, FL, 32224, USA., Ang YS; Social and Cognitive Computing Department, Institute of High Performance Computing, Agency for Science, Technology and Research (A*STAR), Singapore, Singapore., Lockwood P; Centre for Human Brain Health, School of Psychology, University of Birmingham, Birmingham, B15 2TT, UK.; Institute for Mental Health, School of Psychology, University of Birmingham, Birmingham, B15 2TT, UK.; Centre for Developmental Sciences, School of Psychology, University of Birmingham, Birmingham, B15 2TT, UK., Apps MAJ; Centre for Human Brain Health, School of Psychology, University of Birmingham, Birmingham, B15 2TT, UK.; Institute for Mental Health, School of Psychology, University of Birmingham, Birmingham, B15 2TT, UK., Hu P; Department of Neurology, The First Affiliated Hospital of Anhui Medical University, Hefei, 230022, China.; Anhui Province Key Laboratory of Cognition and Neuropsychiatric Disorders, Hefei, 230022, China.; Collaborative Innovation Center of Neuropsychiatric Disorders and Mental Health, Hefei, 230032, China., Wang K; Department of Neurology, The First Affiliated Hospital of Anhui Medical University, Hefei, 230022, China.; School of Mental Health and Psychological Sciences, Anhui Medical University, Hefei, 230032, China.; Anhui Province Key Laboratory of Cognition and Neuropsychiatric Disorders, Hefei, 230022, China.; Collaborative Innovation Center of Neuropsychiatric Disorders and Mental Health, Hefei, 230032, China.; Institute of Artificial Intelligence, Hefei Comprehensive National Science Center, Hefei, 230088, China.; Anhui Institute of Translational Medicine, Hefei, 230000, China., Rowe JB; MRC Cognition and Brain Sciences Unit, University of Cambridge, Cambridge, CB2 7EF, UK.; Department of Clinical Neurosciences, University of Cambridge, Cambridge, CB2 0QQ, UK.; Cambridge University Hospitals NHS Foundation Trust, Cambridge, CB2 0QQ, UK., Le Heron C; Department of Medicine, University of Otago, Christchurch, New Zealand.; New Zealand Brain Research Institute, Christchurch, New Zealand.; Department of Neurology, Christchurch Hospital, Te Whatu Ora Health New Zealand, Christchurch, New Zealand., Husain M; Department of Experimental Psychology, University of Oxford, Oxford, OX1 3EL, UK.; Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, OX3 9DU, UK.; Cognitive Disorders Clinic, John Radcliffe Hospital, Oxford, OX3 9DU, UK.
Source: Translational psychiatry [Transl Psychiatry] 2026 Apr 08; Vol. 16 (1). Date of Electronic Publication: 2026 Apr 08.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: United States NLM ID: 101562664 Publication Model: Electronic Cited Medium: Internet ISSN: 2158-3188 (Electronic) Linking ISSN: 21583188 NLM ISO Abbreviation: Transl Psychiatry Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: The social dimension of apathy: evidence for a distinct domain from 11,243 individuals across health and neurocognitive disorders.
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  Data: <searchLink fieldCode="AU" term="%22Zhao+S%22">Zhao S</searchLink>; Department of Experimental Psychology, University of Oxford, Oxford, OX1 3EL, UK. sijia.zhao@psy.ox.ac.uk.<br /><searchLink fieldCode="AU" term="%22Ye+R%22">Ye R</searchLink>; Department of Neurology, The First Affiliated Hospital of Anhui Medical University, Hefei, 230022, China.; School of Mental Health and Psychological Sciences, Anhui Medical University, Hefei, 230032, China.; Anhui Province Key Laboratory of Cognition and Neuropsychiatric Disorders, Hefei, 230022, China.; Collaborative Innovation Center of Neuropsychiatric Disorders and Mental Health, Hefei, 230032, China.<br /><searchLink fieldCode="AU" term="%22Tang+QY%22">Tang QY</searchLink>; Department of Physics, Hong Kong Baptist University, Hong Kong, China.<br /><searchLink fieldCode="AU" term="%22Attaallah+B%22">Attaallah B</searchLink>; Department of Brain Sciences, Imperial College London, London, W12 0BZ, UK.; Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, OX3 9DU, UK.<br /><searchLink fieldCode="AU" term="%22Toniolo+S%22">Toniolo S</searchLink>; Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, OX3 9DU, UK.; Cognitive Disorders Clinic, John Radcliffe Hospital, Oxford, OX3 9DU, UK.<br /><searchLink fieldCode="AU" term="%22Saleh+Y%22">Saleh Y</searchLink>; Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, OX3 9DU, UK.; Cognitive Disorders Clinic, John Radcliffe Hospital, Oxford, OX3 9DU, UK.<br /><searchLink fieldCode="AU" term="%22Rouse+MA%22">Rouse MA</searchLink>; MRC Cognition and Brain Sciences Unit, University of Cambridge, Cambridge, CB2 7EF, UK.<br /><searchLink fieldCode="AU" term="%22Garrard+P%22">Garrard P</searchLink>; School of Health and Medical Sciences, City St George's, University of London, London, SW17 0RE, UK.<br /><searchLink fieldCode="AU" term="%22Broulidakis+MJ%22">Broulidakis MJ</searchLink>; Department of Experimental Psychology, University of Oxford, Oxford, OX1 3EL, UK.; Cognitive Disorders Clinic, John Radcliffe Hospital, Oxford, OX3 9DU, UK.<br /><searchLink fieldCode="AU" term="%22Thompson+S%22">Thompson S</searchLink>; Cognitive Disorders Clinic, John Radcliffe Hospital, Oxford, OX3 9DU, UK.<br /><searchLink fieldCode="AU" term="%22Manohar+SG%22">Manohar SG</searchLink>; Department of Experimental Psychology, University of Oxford, Oxford, OX1 3EL, UK.; Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, OX3 9DU, UK.; Cognitive Disorders Clinic, John Radcliffe Hospital, Oxford, OX3 9DU, UK.<br /><searchLink fieldCode="AU" term="%22Irani+SR%22">Irani SR</searchLink>; Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, OX3 9DU, UK.; Department of Neurology, Mayo Clinic, Jacksonville, FL, 32224, USA.; Department of Neurosciences, Mayo Clinic, Jacksonville, FL, 32224, USA.<br /><searchLink fieldCode="AU" term="%22Ang+YS%22">Ang YS</searchLink>; Social and Cognitive Computing Department, Institute of High Performance Computing, Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Lockwood+P%22">Lockwood P</searchLink>; Centre for Human Brain Health, School of Psychology, University of Birmingham, Birmingham, B15 2TT, UK.; Institute for Mental Health, School of Psychology, University of Birmingham, Birmingham, B15 2TT, UK.; Centre for Developmental Sciences, School of Psychology, University of Birmingham, Birmingham, B15 2TT, UK.<br /><searchLink fieldCode="AU" term="%22Apps+MAJ%22">Apps MAJ</searchLink>; Centre for Human Brain Health, School of Psychology, University of Birmingham, Birmingham, B15 2TT, UK.; Institute for Mental Health, School of Psychology, University of Birmingham, Birmingham, B15 2TT, UK.<br /><searchLink fieldCode="AU" term="%22Hu+P%22">Hu P</searchLink>; Department of Neurology, The First Affiliated Hospital of Anhui Medical University, Hefei, 230022, China.; Anhui Province Key Laboratory of Cognition and Neuropsychiatric Disorders, Hefei, 230022, China.; Collaborative Innovation Center of Neuropsychiatric Disorders and Mental Health, Hefei, 230032, China.<br /><searchLink fieldCode="AU" term="%22Wang+K%22">Wang K</searchLink>; Department of Neurology, The First Affiliated Hospital of Anhui Medical University, Hefei, 230022, China.; School of Mental Health and Psychological Sciences, Anhui Medical University, Hefei, 230032, China.; Anhui Province Key Laboratory of Cognition and Neuropsychiatric Disorders, Hefei, 230022, China.; Collaborative Innovation Center of Neuropsychiatric Disorders and Mental Health, Hefei, 230032, China.; Institute of Artificial Intelligence, Hefei Comprehensive National Science Center, Hefei, 230088, China.; Anhui Institute of Translational Medicine, Hefei, 230000, China.<br /><searchLink fieldCode="AU" term="%22Rowe+JB%22">Rowe JB</searchLink>; MRC Cognition and Brain Sciences Unit, University of Cambridge, Cambridge, CB2 7EF, UK.; Department of Clinical Neurosciences, University of Cambridge, Cambridge, CB2 0QQ, UK.; Cambridge University Hospitals NHS Foundation Trust, Cambridge, CB2 0QQ, UK.<br /><searchLink fieldCode="AU" term="%22Le+Heron+C%22">Le Heron C</searchLink>; Department of Medicine, University of Otago, Christchurch, New Zealand.; New Zealand Brain Research Institute, Christchurch, New Zealand.; Department of Neurology, Christchurch Hospital, Te Whatu Ora Health New Zealand, Christchurch, New Zealand.<br /><searchLink fieldCode="AU" term="%22Husain+M%22">Husain M</searchLink>; Department of Experimental Psychology, University of Oxford, Oxford, OX1 3EL, UK.; Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, OX3 9DU, UK.; Cognitive Disorders Clinic, John Radcliffe Hospital, Oxford, OX3 9DU, UK.
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  Data: <searchLink fieldCode="JN" term="%22101562664%22">Translational psychiatry</searchLink> [Transl Psychiatry] 2026 Apr 08; Vol. 16 (1). <i>Date of Electronic Publication: </i>2026 Apr 08.
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