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RIP kinase inhibition with Necrostatin-1 improves human marginal mass islet graft survival and function for the management of type 1 diabetes.

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Title: RIP kinase inhibition with Necrostatin-1 improves human marginal mass islet graft survival and function for the management of type 1 diabetes.
Authors: Aggarwal S; Department of Surgery, University of Alberta, Edmonton, AB, Canada.; Alberta Diabetes Institute, University of Alberta, Edmonton, AB, Canada., Cuesta-Gomez N; Department of Surgery, University of Alberta, Edmonton, AB, Canada.; Alberta Diabetes Institute, University of Alberta, Edmonton, AB, Canada., Paramor J; Department of Surgery, University of Alberta, Edmonton, AB, Canada.; Alberta Diabetes Institute, University of Alberta, Edmonton, AB, Canada., Kelly S; Department of Surgery, University of Alberta, Edmonton, AB, Canada.; Alberta Diabetes Institute, University of Alberta, Edmonton, AB, Canada., Polishevska K; Department of Surgery, University of Alberta, Edmonton, AB, Canada.; Alberta Diabetes Institute, University of Alberta, Edmonton, AB, Canada., Seeberger K; Department of Surgery, University of Alberta, Edmonton, AB, Canada.; Alberta Diabetes Institute, University of Alberta, Edmonton, AB, Canada., Worton J; Department of Surgery, University of Alberta, Edmonton, AB, Canada.; Alberta Diabetes Institute, University of Alberta, Edmonton, AB, Canada., Kuppan P; Department of Surgery, University of Alberta, Edmonton, AB, Canada.; Alberta Diabetes Institute, University of Alberta, Edmonton, AB, Canada., Pepper AR; Department of Surgery, University of Alberta, Edmonton, AB, Canada. apepper@ualberta.ca.; Alberta Diabetes Institute, University of Alberta, Edmonton, AB, Canada. apepper@ualberta.ca.
Source: Cell death & disease [Cell Death Dis] 2026 Apr 08; Vol. 17 (1). Date of Electronic Publication: 2026 Apr 08.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101524092 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-4889 (Electronic) NLM ISO Abbreviation: Cell Death Dis Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: RIP kinase inhibition with Necrostatin-1 improves human marginal mass islet graft survival and function for the management of type 1 diabetes.
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  Data: <searchLink fieldCode="AU" term="%22Aggarwal+S%22">Aggarwal S</searchLink>; Department of Surgery, University of Alberta, Edmonton, AB, Canada.; Alberta Diabetes Institute, University of Alberta, Edmonton, AB, Canada.<br /><searchLink fieldCode="AU" term="%22Cuesta-Gomez+N%22">Cuesta-Gomez N</searchLink>; Department of Surgery, University of Alberta, Edmonton, AB, Canada.; Alberta Diabetes Institute, University of Alberta, Edmonton, AB, Canada.<br /><searchLink fieldCode="AU" term="%22Paramor+J%22">Paramor J</searchLink>; Department of Surgery, University of Alberta, Edmonton, AB, Canada.; Alberta Diabetes Institute, University of Alberta, Edmonton, AB, Canada.<br /><searchLink fieldCode="AU" term="%22Kelly+S%22">Kelly S</searchLink>; Department of Surgery, University of Alberta, Edmonton, AB, Canada.; Alberta Diabetes Institute, University of Alberta, Edmonton, AB, Canada.<br /><searchLink fieldCode="AU" term="%22Polishevska+K%22">Polishevska K</searchLink>; Department of Surgery, University of Alberta, Edmonton, AB, Canada.; Alberta Diabetes Institute, University of Alberta, Edmonton, AB, Canada.<br /><searchLink fieldCode="AU" term="%22Seeberger+K%22">Seeberger K</searchLink>; Department of Surgery, University of Alberta, Edmonton, AB, Canada.; Alberta Diabetes Institute, University of Alberta, Edmonton, AB, Canada.<br /><searchLink fieldCode="AU" term="%22Worton+J%22">Worton J</searchLink>; Department of Surgery, University of Alberta, Edmonton, AB, Canada.; Alberta Diabetes Institute, University of Alberta, Edmonton, AB, Canada.<br /><searchLink fieldCode="AU" term="%22Kuppan+P%22">Kuppan P</searchLink>; Department of Surgery, University of Alberta, Edmonton, AB, Canada.; Alberta Diabetes Institute, University of Alberta, Edmonton, AB, Canada.<br /><searchLink fieldCode="AU" term="%22Pepper+AR%22">Pepper AR</searchLink>; Department of Surgery, University of Alberta, Edmonton, AB, Canada. apepper@ualberta.ca.; Alberta Diabetes Institute, University of Alberta, Edmonton, AB, Canada. apepper@ualberta.ca.
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  Data: <searchLink fieldCode="JN" term="%22101524092%22">Cell death & disease</searchLink> [Cell Death Dis] 2026 Apr 08; Vol. 17 (1). <i>Date of Electronic Publication: </i>2026 Apr 08.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Pub%2E+Group%22">Nature Pub. Group </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101524092 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2041-4889 (Electronic) <i>NLM ISO Abbreviation: </i>Cell Death Dis <i>Subsets: </i>MEDLINE
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        Value: 10.1038/s41419-026-08728-8
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        Text: English
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      – TitleFull: RIP kinase inhibition with Necrostatin-1 improves human marginal mass islet graft survival and function for the management of type 1 diabetes.
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              Text: 2026 Apr 08
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