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Cell loss disrupts mechanical homeostasis to drive retinal pigment epithelium ageing-like phenotype in vitro.

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Title: Cell loss disrupts mechanical homeostasis to drive retinal pigment epithelium ageing-like phenotype in vitro.
Authors: Piskova T; Institute of Molecular and Cellular Anatomy, RWTH Aachen University, Aachen, Germany., Kozyrina AN; Centre for the Cellular Microenvironment, James Watt School of Engineering, University of Glasgow, Glasgow, UK., Astrauskaitė G; Centre for the Cellular Microenvironment, James Watt School of Engineering, University of Glasgow, Glasgow, UK., Mabrouk ME; Institute of Stem Cell Biology, University Hospital of RWTH Aachen, Aachen, Germany., Schepl S; Institute of Molecular and Cellular Anatomy, RWTH Aachen University, Aachen, Germany., Yam SLS; Institute of Molecular and Cellular Anatomy, RWTH Aachen University, Aachen, Germany., Ravithas R; Institute of Molecular and Cellular Anatomy, RWTH Aachen University, Aachen, Germany., Wagner W; Institute of Stem Cell Biology, University Hospital of RWTH Aachen, Aachen, Germany., Vassalli M; Centre for the Cellular Microenvironment, James Watt School of Engineering, University of Glasgow, Glasgow, UK., Di Russo J; Institute of Molecular and Cellular Anatomy, RWTH Aachen University, Aachen, Germany. jdirusso@ukaachen.de.; DWI-Leibniz-Institute for Interactive Materials, Aachen, Germany. jdirusso@ukaachen.de.
Source: Nature communications [Nat Commun] 2026 Apr 08; Vol. 17 (1). Date of Electronic Publication: 2026 Apr 08.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Cell loss disrupts mechanical homeostasis to drive retinal pigment epithelium ageing-like phenotype in vitro.
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  Data: <searchLink fieldCode="AU" term="%22Piskova+T%22">Piskova T</searchLink>; Institute of Molecular and Cellular Anatomy, RWTH Aachen University, Aachen, Germany.<br /><searchLink fieldCode="AU" term="%22Kozyrina+AN%22">Kozyrina AN</searchLink>; Centre for the Cellular Microenvironment, James Watt School of Engineering, University of Glasgow, Glasgow, UK.<br /><searchLink fieldCode="AU" term="%22Astrauskaitė+G%22">Astrauskaitė G</searchLink>; Centre for the Cellular Microenvironment, James Watt School of Engineering, University of Glasgow, Glasgow, UK.<br /><searchLink fieldCode="AU" term="%22Mabrouk+ME%22">Mabrouk ME</searchLink>; Institute of Stem Cell Biology, University Hospital of RWTH Aachen, Aachen, Germany.<br /><searchLink fieldCode="AU" term="%22Schepl+S%22">Schepl S</searchLink>; Institute of Molecular and Cellular Anatomy, RWTH Aachen University, Aachen, Germany.<br /><searchLink fieldCode="AU" term="%22Yam+SLS%22">Yam SLS</searchLink>; Institute of Molecular and Cellular Anatomy, RWTH Aachen University, Aachen, Germany.<br /><searchLink fieldCode="AU" term="%22Ravithas+R%22">Ravithas R</searchLink>; Institute of Molecular and Cellular Anatomy, RWTH Aachen University, Aachen, Germany.<br /><searchLink fieldCode="AU" term="%22Wagner+W%22">Wagner W</searchLink>; Institute of Stem Cell Biology, University Hospital of RWTH Aachen, Aachen, Germany.<br /><searchLink fieldCode="AU" term="%22Vassalli+M%22">Vassalli M</searchLink>; Centre for the Cellular Microenvironment, James Watt School of Engineering, University of Glasgow, Glasgow, UK.<br /><searchLink fieldCode="AU" term="%22Di+Russo+J%22">Di Russo J</searchLink>; Institute of Molecular and Cellular Anatomy, RWTH Aachen University, Aachen, Germany. jdirusso@ukaachen.de.; DWI-Leibniz-Institute for Interactive Materials, Aachen, Germany. jdirusso@ukaachen.de.
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  Data: <searchLink fieldCode="JN" term="%22101528555%22">Nature communications</searchLink> [Nat Commun] 2026 Apr 08; Vol. 17 (1). <i>Date of Electronic Publication: </i>2026 Apr 08.
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              Text: 2026 Apr 08
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