IL-1-mediated inflammation promotes metastatic dissemination and resistance to EGFR-targeted therapy.
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| Title: | IL-1-mediated inflammation promotes metastatic dissemination and resistance to EGFR-targeted therapy. |
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| Authors: | Pagano F; Department of Medical and Surgical Sciences, University of Bologna, Bologna, Italy., Girone C; Department of Medical and Surgical Sciences, University of Bologna, Bologna, Italy., Borrelli F; Department of Medical and Surgical Sciences, University of Bologna, Bologna, Italy., Romaniello D; Department of Medical and Surgical Sciences, University of Bologna, Bologna, Italy.; IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy., Gelfo V; IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy., Filippini DM; IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy., Morselli A; Department of Medical and Surgical Sciences, University of Bologna, Bologna, Italy., Mazzeschi M; IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy., Querzoli G; IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy., Ambrosi F; Department of Medical and Surgical Sciences, University of Bologna, Bologna, Italy.; Pathology Unit, Maggiore Hospital-AUSL Bologna, Bologna, Italy., Miano C; IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy., D'Uva G; Department of Medical and Surgical Sciences, University of Bologna, Bologna, Italy.; IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy., Fazi F; Department of Wellbeing, Health and Environmental Sustainability (BeSSA), Sapienza University of Rome, Rome, Italy., Chaluvally-Raghavan P; Department of Obstetrics and Gynecology, Medical College of Wisconsin, Milwaukee, WI, USA.; Medical College of Wisconsin Cancer Center, Medical College of Wisconsin, Milwaukee, WI, USA., Sgarzi M; IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy. michela.sgarzi@aosp.bo.it., Győrffy B; Department of Bioinformatics, Semmelweis University, Budapest, Hungary.; Institute of Transdisciplinary Discoveries, Medical School, University of Pecs, Pecs, Hungary.; Cancer Biomarker Research Group, Institute of Molecular Life Sciences, HUN-REN Research Centre for Natural Sciences, Budapest, Hungary., Ardizzoni A; IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy., Lauriola M; Department of Medical and Surgical Sciences, University of Bologna, Bologna, Italy. mattia.lauriola2@unibo.it.; IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy. mattia.lauriola2@unibo.it. |
| Source: | NPJ precision oncology [NPJ Precis Oncol] 2026 Apr 08; Vol. 10 (1). Date of Electronic Publication: 2026 Apr 08. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Springer Nature Country of Publication: England NLM ID: 101708166 Publication Model: Electronic Cited Medium: Print ISSN: 2397-768X (Print) Linking ISSN: 2397768X NLM ISO Abbreviation: NPJ Precis Oncol Subsets: PubMed not MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2397-768X |
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| DOI: | 10.1038/s41698-026-01389-y |