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IL-1-mediated inflammation promotes metastatic dissemination and resistance to EGFR-targeted therapy.

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Title: IL-1-mediated inflammation promotes metastatic dissemination and resistance to EGFR-targeted therapy.
Authors: Pagano F; Department of Medical and Surgical Sciences, University of Bologna, Bologna, Italy., Girone C; Department of Medical and Surgical Sciences, University of Bologna, Bologna, Italy., Borrelli F; Department of Medical and Surgical Sciences, University of Bologna, Bologna, Italy., Romaniello D; Department of Medical and Surgical Sciences, University of Bologna, Bologna, Italy.; IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy., Gelfo V; IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy., Filippini DM; IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy., Morselli A; Department of Medical and Surgical Sciences, University of Bologna, Bologna, Italy., Mazzeschi M; IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy., Querzoli G; IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy., Ambrosi F; Department of Medical and Surgical Sciences, University of Bologna, Bologna, Italy.; Pathology Unit, Maggiore Hospital-AUSL Bologna, Bologna, Italy., Miano C; IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy., D'Uva G; Department of Medical and Surgical Sciences, University of Bologna, Bologna, Italy.; IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy., Fazi F; Department of Wellbeing, Health and Environmental Sustainability (BeSSA), Sapienza University of Rome, Rome, Italy., Chaluvally-Raghavan P; Department of Obstetrics and Gynecology, Medical College of Wisconsin, Milwaukee, WI, USA.; Medical College of Wisconsin Cancer Center, Medical College of Wisconsin, Milwaukee, WI, USA., Sgarzi M; IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy. michela.sgarzi@aosp.bo.it., Győrffy B; Department of Bioinformatics, Semmelweis University, Budapest, Hungary.; Institute of Transdisciplinary Discoveries, Medical School, University of Pecs, Pecs, Hungary.; Cancer Biomarker Research Group, Institute of Molecular Life Sciences, HUN-REN Research Centre for Natural Sciences, Budapest, Hungary., Ardizzoni A; IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy., Lauriola M; Department of Medical and Surgical Sciences, University of Bologna, Bologna, Italy. mattia.lauriola2@unibo.it.; IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy. mattia.lauriola2@unibo.it.
Source: NPJ precision oncology [NPJ Precis Oncol] 2026 Apr 08; Vol. 10 (1). Date of Electronic Publication: 2026 Apr 08.
Publication Type: Journal Article
Journal Info: Publisher: Springer Nature Country of Publication: England NLM ID: 101708166 Publication Model: Electronic Cited Medium: Print ISSN: 2397-768X (Print) Linking ISSN: 2397768X NLM ISO Abbreviation: NPJ Precis Oncol Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: IL-1-mediated inflammation promotes metastatic dissemination and resistance to EGFR-targeted therapy.
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  Data: <searchLink fieldCode="AU" term="%22Pagano+F%22">Pagano F</searchLink>; Department of Medical and Surgical Sciences, University of Bologna, Bologna, Italy.<br /><searchLink fieldCode="AU" term="%22Girone+C%22">Girone C</searchLink>; Department of Medical and Surgical Sciences, University of Bologna, Bologna, Italy.<br /><searchLink fieldCode="AU" term="%22Borrelli+F%22">Borrelli F</searchLink>; Department of Medical and Surgical Sciences, University of Bologna, Bologna, Italy.<br /><searchLink fieldCode="AU" term="%22Romaniello+D%22">Romaniello D</searchLink>; Department of Medical and Surgical Sciences, University of Bologna, Bologna, Italy.; IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy.<br /><searchLink fieldCode="AU" term="%22Gelfo+V%22">Gelfo V</searchLink>; IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy.<br /><searchLink fieldCode="AU" term="%22Filippini+DM%22">Filippini DM</searchLink>; IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy.<br /><searchLink fieldCode="AU" term="%22Morselli+A%22">Morselli A</searchLink>; Department of Medical and Surgical Sciences, University of Bologna, Bologna, Italy.<br /><searchLink fieldCode="AU" term="%22Mazzeschi+M%22">Mazzeschi M</searchLink>; IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy.<br /><searchLink fieldCode="AU" term="%22Querzoli+G%22">Querzoli G</searchLink>; IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy.<br /><searchLink fieldCode="AU" term="%22Ambrosi+F%22">Ambrosi F</searchLink>; Department of Medical and Surgical Sciences, University of Bologna, Bologna, Italy.; Pathology Unit, Maggiore Hospital-AUSL Bologna, Bologna, Italy.<br /><searchLink fieldCode="AU" term="%22Miano+C%22">Miano C</searchLink>; IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy.<br /><searchLink fieldCode="AU" term="%22D'Uva+G%22">D'Uva G</searchLink>; Department of Medical and Surgical Sciences, University of Bologna, Bologna, Italy.; IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy.<br /><searchLink fieldCode="AU" term="%22Fazi+F%22">Fazi F</searchLink>; Department of Wellbeing, Health and Environmental Sustainability (BeSSA), Sapienza University of Rome, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Chaluvally-Raghavan+P%22">Chaluvally-Raghavan P</searchLink>; Department of Obstetrics and Gynecology, Medical College of Wisconsin, Milwaukee, WI, USA.; Medical College of Wisconsin Cancer Center, Medical College of Wisconsin, Milwaukee, WI, USA.<br /><searchLink fieldCode="AU" term="%22Sgarzi+M%22">Sgarzi M</searchLink>; IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy. michela.sgarzi@aosp.bo.it.<br /><searchLink fieldCode="AU" term="%22Győrffy+B%22">Győrffy B</searchLink>; Department of Bioinformatics, Semmelweis University, Budapest, Hungary.; Institute of Transdisciplinary Discoveries, Medical School, University of Pecs, Pecs, Hungary.; Cancer Biomarker Research Group, Institute of Molecular Life Sciences, HUN-REN Research Centre for Natural Sciences, Budapest, Hungary.<br /><searchLink fieldCode="AU" term="%22Ardizzoni+A%22">Ardizzoni A</searchLink>; IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy.<br /><searchLink fieldCode="AU" term="%22Lauriola+M%22">Lauriola M</searchLink>; Department of Medical and Surgical Sciences, University of Bologna, Bologna, Italy. mattia.lauriola2@unibo.it.; IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy. mattia.lauriola2@unibo.it.
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  Data: <searchLink fieldCode="JN" term="%22101708166%22">NPJ precision oncology</searchLink> [NPJ Precis Oncol] 2026 Apr 08; Vol. 10 (1). <i>Date of Electronic Publication: </i>2026 Apr 08.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Springer+Nature%22">Springer Nature </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101708166 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Print <i>ISSN: </i>2397-768X (Print) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%222397768X%22">2397768X </searchLink><i>NLM ISO Abbreviation: </i>NPJ Precis Oncol <i>Subsets: </i>PubMed not MEDLINE
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