A sstR2-targeted radiohybrid theranostic agent for PET imaging and β- therapy with excellent preclinical performance.

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Title: A sstR2-targeted radiohybrid theranostic agent for PET imaging and β- therapy with excellent preclinical performance.
Authors: Deiser S; Chair of Medicinal and Bioinorganic Chemistry, Department of Chemistry, School of Natural Sciences, Technical University of Munich, München, 85748, Germany.; Chair of Pharmaceutical Radiochemistry, Department of Chemistry, School of Natural Sciences, Technical University of Munich, München, 85748, Germany., Fenzl S; Chair of Medicinal and Bioinorganic Chemistry, Department of Chemistry, School of Natural Sciences, Technical University of Munich, München, 85748, Germany.; Chair of Silicon Chemistry, Department of Chemistry, School of Natural Sciences, Technical University of Munich, München, 85748, Germany., König V; Chair of Medicinal and Bioinorganic Chemistry, Department of Chemistry, School of Natural Sciences, Technical University of Munich, München, 85748, Germany.; Chair of Pharmaceutical Radiochemistry, Department of Chemistry, School of Natural Sciences, Technical University of Munich, München, 85748, Germany., Inoue S; Chair of Silicon Chemistry, Department of Chemistry, School of Natural Sciences, Technical University of Munich, München, 85748, Germany. s.inoue@tum.de., Casini A; Chair of Medicinal and Bioinorganic Chemistry, Department of Chemistry, School of Natural Sciences, Technical University of Munich, München, 85748, Germany. angela.casini@tum.de.; Chair of Pharmaceutical Radiochemistry, Department of Chemistry, School of Natural Sciences, Technical University of Munich, München, 85748, Germany. angela.casini@tum.de.
Source: Npj imaging [Npj Imaging] 2026 Apr 08; Vol. 4 (1). Date of Electronic Publication: 2026 Apr 08.
Publication Type: Journal Article
Journal Info: Publisher: Springer Nature Country of Publication: Switzerland NLM ID: 9918733285306676 Publication Model: Electronic Cited Medium: Internet ISSN: 2948-197X (Electronic) Linking ISSN: 2948197X NLM ISO Abbreviation: Npj Imaging Subsets: PubMed not MEDLINE
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  Data: A sstR2-targeted radiohybrid theranostic agent for PET imaging and β<superscript>-</superscript> therapy with excellent preclinical performance.
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  Data: <searchLink fieldCode="AU" term="%22Deiser+S%22">Deiser S</searchLink>; Chair of Medicinal and Bioinorganic Chemistry, Department of Chemistry, School of Natural Sciences, Technical University of Munich, München, 85748, Germany.; Chair of Pharmaceutical Radiochemistry, Department of Chemistry, School of Natural Sciences, Technical University of Munich, München, 85748, Germany.<br /><searchLink fieldCode="AU" term="%22Fenzl+S%22">Fenzl S</searchLink>; Chair of Medicinal and Bioinorganic Chemistry, Department of Chemistry, School of Natural Sciences, Technical University of Munich, München, 85748, Germany.; Chair of Silicon Chemistry, Department of Chemistry, School of Natural Sciences, Technical University of Munich, München, 85748, Germany.<br /><searchLink fieldCode="AU" term="%22König+V%22">König V</searchLink>; Chair of Medicinal and Bioinorganic Chemistry, Department of Chemistry, School of Natural Sciences, Technical University of Munich, München, 85748, Germany.; Chair of Pharmaceutical Radiochemistry, Department of Chemistry, School of Natural Sciences, Technical University of Munich, München, 85748, Germany.<br /><searchLink fieldCode="AU" term="%22Inoue+S%22">Inoue S</searchLink>; Chair of Silicon Chemistry, Department of Chemistry, School of Natural Sciences, Technical University of Munich, München, 85748, Germany. s.inoue@tum.de.<br /><searchLink fieldCode="AU" term="%22Casini+A%22">Casini A</searchLink>; Chair of Medicinal and Bioinorganic Chemistry, Department of Chemistry, School of Natural Sciences, Technical University of Munich, München, 85748, Germany. angela.casini@tum.de.; Chair of Pharmaceutical Radiochemistry, Department of Chemistry, School of Natural Sciences, Technical University of Munich, München, 85748, Germany. angela.casini@tum.de.
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        Value: 10.1038/s44303-026-00155-w
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              Text: 2026 Apr 08
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