A penicillin-binding protein inhibitor series to target drug-resistant Neisseria gonorrhoeae.

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Title: A penicillin-binding protein inhibitor series to target drug-resistant Neisseria gonorrhoeae.
Authors: Uehara T; Venatorx Pharmaceuticals, Inc., Malvern, PA, USA. tsuyoshi.uehara@gmail.com., Zulli AL; Venatorx Pharmaceuticals, Inc., Malvern, PA, USA., Miller B; Venatorx Pharmaceuticals, Inc., Malvern, PA, USA., Avery LM; Venatorx Pharmaceuticals, Inc., Malvern, PA, USA., Boyd SA; Venatorx Pharmaceuticals, Inc., Malvern, PA, USA., Chatwin CL; Venatorx Pharmaceuticals, Inc., Malvern, PA, USA., Chu GH; Venatorx Pharmaceuticals, Inc., Malvern, PA, USA., Drager AS; Venatorx Pharmaceuticals, Inc., Malvern, PA, USA., Edwards M; Venatorx Pharmaceuticals, Inc., Malvern, PA, USA., Emeigh Hart SG; Venatorx Pharmaceuticals, Inc., Malvern, PA, USA., Line NJ; Venatorx Pharmaceuticals, Inc., Malvern, PA, USA., Myers CL; Venatorx Pharmaceuticals, Inc., Malvern, PA, USA., Rongala G; Venatorx Pharmaceuticals, Inc., Malvern, PA, USA., Stevenson A; Venatorx Pharmaceuticals, Inc., Malvern, PA, USA., Uehara K; Venatorx Pharmaceuticals, Inc., Malvern, PA, USA., Yi F; Venatorx Pharmaceuticals, Inc., Malvern, PA, USA., Wang B; BioDuro-Sundia, Beijing, China., Liu Z; BioDuro-Sundia, Beijing, China., Wang M; BioDuro-Sundia, Beijing, China., Zhao Z; BioDuro-Sundia, Beijing, China., Zhou X; BioDuro-Sundia, Beijing, China., Zhao H; BioDuro-Sundia, Beijing, China., Stratton CM; Department of Biochemistry and Molecular Biology, University of South Alabama, Mobile, AL, USA., Bala S; Department of Biochemistry and Molecular Biology, University of South Alabama, Mobile, AL, USA., Davies C; Department of Biochemistry and Molecular Biology, University of South Alabama, Mobile, AL, USA., Tkavc R; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA.; Department of Microbiology and Immunology, Uniformed Services University of the Health Sciences, Bethesda, MD, USA., Jerse AE; Department of Microbiology and Immunology, Uniformed Services University of the Health Sciences, Bethesda, MD, USA., Pevear DC; Venatorx Pharmaceuticals, Inc., Malvern, PA, USA.; Spring Mill Pharma Inc., Malvern, PA, USA., Burns CJ; Venatorx Pharmaceuticals, Inc., Malvern, PA, USA., Daigle DM; Venatorx Pharmaceuticals, Inc., Malvern, PA, USA., Condon SM; Venatorx Pharmaceuticals, Inc., Malvern, PA, USA. stephencondon3418@gmail.com.
Source: Nature microbiology [Nat Microbiol] 2026 May; Vol. 11 (5), pp. 1348-1360. Date of Electronic Publication: 2026 Apr 08.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101674869 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2058-5276 (Electronic) Linking ISSN: 20585276 NLM ISO Abbreviation: Nat Microbiol Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2058-5276
DOI:10.1038/s41564-026-02309-3