Efficacy of local convection enhanced delivery of chemotherapy using an intracerebral osmotic pump in a rat model of glioblastoma.

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Title: Efficacy of local convection enhanced delivery of chemotherapy using an intracerebral osmotic pump in a rat model of glioblastoma.
Authors: McDaid J; Department of Neurosurgery, Endeavor Health, Evanston, IL, United States.; Pritzker School of Medicine, Chicago, IL, United States., Bailes JE; Department of Neurosurgery, Endeavor Health, Evanston, IL, United States.; Pritzker School of Medicine, University of Chicago, Chicago, IL, United States.; Deep Brain BCI Corp, Wilmington, DE, United States., Jha NK; Deep Brain BCI Corp, Wilmington, DE, United States., Bobustuc G; Intent Medical Group, Endeavor Health Advanced Neurosciences Institute, Arlington Heights, IL, United States., Berlet R; Department of Neurosurgery, Endeavor Health, Evanston, IL, United States., Kessinger C; Department of Neurosurgery, Endeavor Health, Evanston, IL, United States., Whitcomb E; Department of Neurosurgery, Endeavor Health, Evanston, IL, United States., Lee JM; Pritzker School of Medicine, University of Chicago, Chicago, IL, United States.; Department of Pathology, Endeavor Health, Evanston, IL, United States., Aksenov DP; Pritzker School of Medicine, University of Chicago, Chicago, IL, United States.; Department of Radiology, Endeavor Health, Evanston, IL, United States.; Department of Anesthesiology, Endeavor Health, Evanston, IL, United States., Walker M; Department of Radiology, Endeavor Health, Evanston, IL, United States., Azapagic A; Department of Mechanical Engineering, The University of Utah, Salt Lake, UT, United States., Bookwalter J; Department of Biomedical Engineering, The University of Utah, Salt Lake, UT, United States., Ullah A; Department of Biomedical Engineering, The University of Utah, Salt Lake, UT, United States., Sant H; Department of Chemical Engineering, The University of Utah, Salt Lake, UT, United States., Shea J; Department of Biomedical Engineering, The University of Utah, Salt Lake, UT, United States.; Department of Surgery, University of Utah School of Medicine, Salt Lake, UT, United States., Gale BK; Department of Mechanical Engineering, The University of Utah, Salt Lake, UT, United States.; Department of Biomedical Engineering, The University of Utah, Salt Lake, UT, United States.
Source: Frontiers in oncology [Front Oncol] 2026 Mar 04; Vol. 16, pp. 1775053. Date of Electronic Publication: 2026 Mar 04 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101568867 Publication Model: eCollection Cited Medium: Print ISSN: 2234-943X (Print) Linking ISSN: 2234943X NLM ISO Abbreviation: Front Oncol Subsets: PubMed not MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22McDaid+J%22">McDaid J</searchLink>; Department of Neurosurgery, Endeavor Health, Evanston, IL, United States.; Pritzker School of Medicine, Chicago, IL, United States.<br /><searchLink fieldCode="AU" term="%22Bailes+JE%22">Bailes JE</searchLink>; Department of Neurosurgery, Endeavor Health, Evanston, IL, United States.; Pritzker School of Medicine, University of Chicago, Chicago, IL, United States.; Deep Brain BCI Corp, Wilmington, DE, United States.<br /><searchLink fieldCode="AU" term="%22Jha+NK%22">Jha NK</searchLink>; Deep Brain BCI Corp, Wilmington, DE, United States.<br /><searchLink fieldCode="AU" term="%22Bobustuc+G%22">Bobustuc G</searchLink>; Intent Medical Group, Endeavor Health Advanced Neurosciences Institute, Arlington Heights, IL, United States.<br /><searchLink fieldCode="AU" term="%22Berlet+R%22">Berlet R</searchLink>; Department of Neurosurgery, Endeavor Health, Evanston, IL, United States.<br /><searchLink fieldCode="AU" term="%22Kessinger+C%22">Kessinger C</searchLink>; Department of Neurosurgery, Endeavor Health, Evanston, IL, United States.<br /><searchLink fieldCode="AU" term="%22Whitcomb+E%22">Whitcomb E</searchLink>; Department of Neurosurgery, Endeavor Health, Evanston, IL, United States.<br /><searchLink fieldCode="AU" term="%22Lee+JM%22">Lee JM</searchLink>; Pritzker School of Medicine, University of Chicago, Chicago, IL, United States.; Department of Pathology, Endeavor Health, Evanston, IL, United States.<br /><searchLink fieldCode="AU" term="%22Aksenov+DP%22">Aksenov DP</searchLink>; Pritzker School of Medicine, University of Chicago, Chicago, IL, United States.; Department of Radiology, Endeavor Health, Evanston, IL, United States.; Department of Anesthesiology, Endeavor Health, Evanston, IL, United States.<br /><searchLink fieldCode="AU" term="%22Walker+M%22">Walker M</searchLink>; Department of Radiology, Endeavor Health, Evanston, IL, United States.<br /><searchLink fieldCode="AU" term="%22Azapagic+A%22">Azapagic A</searchLink>; Department of Mechanical Engineering, The University of Utah, Salt Lake, UT, United States.<br /><searchLink fieldCode="AU" term="%22Bookwalter+J%22">Bookwalter J</searchLink>; Department of Biomedical Engineering, The University of Utah, Salt Lake, UT, United States.<br /><searchLink fieldCode="AU" term="%22Ullah+A%22">Ullah A</searchLink>; Department of Biomedical Engineering, The University of Utah, Salt Lake, UT, United States.<br /><searchLink fieldCode="AU" term="%22Sant+H%22">Sant H</searchLink>; Department of Chemical Engineering, The University of Utah, Salt Lake, UT, United States.<br /><searchLink fieldCode="AU" term="%22Shea+J%22">Shea J</searchLink>; Department of Biomedical Engineering, The University of Utah, Salt Lake, UT, United States.; Department of Surgery, University of Utah School of Medicine, Salt Lake, UT, United States.<br /><searchLink fieldCode="AU" term="%22Gale+BK%22">Gale BK</searchLink>; Department of Mechanical Engineering, The University of Utah, Salt Lake, UT, United States.; Department of Biomedical Engineering, The University of Utah, Salt Lake, UT, United States.
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  Data: <searchLink fieldCode="JN" term="%22101568867%22">Frontiers in oncology</searchLink> [Front Oncol] 2026 Mar 04; Vol. 16, pp. 1775053. <i>Date of Electronic Publication: </i>2026 Mar 04 (<i>Print Publication: </i>2026).
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