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Takayasu arteritis phenotypes and outcomes: A data-driven cluster analysis from a large international cohort.

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Title: Takayasu arteritis phenotypes and outcomes: A data-driven cluster analysis from a large international cohort.
Authors: Vieira M; Sorbonne Universités AP-HP, Groupe Hospitalier Pitié-Salpêtrière, Département de Médecine Interne et Immunologie Clinique, F-75013, Centre National de Référence Maladies Autoimmunes Systémiques Rares, Centre National de Référence Maladies Autoinflammatoires et Amylose Inflammatoire (CEREMAIA), Inflammation-Immunopathology-Biotherapy Department (DMU 3iD), CIC Biotherapy, INSERM 959, Groupe Hospitalier Pitié-Salpetriere, AP-HP, Paris, France; Rheumatology Division, Department of Internal Medicine, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil., Ghayad E; Sorbonne Universités AP-HP, Groupe Hospitalier Pitié-Salpêtrière, Département de Médecine Interne et Immunologie Clinique, F-75013, Centre National de Référence Maladies Autoimmunes Systémiques Rares, Centre National de Référence Maladies Autoinflammatoires et Amylose Inflammatoire (CEREMAIA), Inflammation-Immunopathology-Biotherapy Department (DMU 3iD), CIC Biotherapy, INSERM 959, Groupe Hospitalier Pitié-Salpetriere, AP-HP, Paris, France., Aeschlimann FA; Department of Rheumatology, University Children's Hospital Basel UKBB, Basel, Switzerland., Peres Lima JP; Rheumatology Division, Department of Medicine, Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, SP, Brazil., Marvisi C; Division of Rheumatology, Azienda USL-IRCCS di Reggio Emilia and Università di Modena e Reggio Emilia, Reggio Emilia, Italy., Iacomelli G; Department of Internal Medicine, ASST Fatebenefratelli-Sacco, Fatebenefratelli Hospital, 20121, Milan, Italy., Mekinian A; Department of Internal Medicine, Sorbonne Universités, AP-HP, Hôpital Saint-Antoine, Centre National de Référence Maladies Autoimmunes Systémiques Rares, Centre National de Référence Maladies Autoinflammatoires et Amylose Inflammatoire (CEREMAIA), Inflammation-Immunopathology-Biotherapy Department (DMU 3iD), Paris, France., Koné-Paut I; Department of Pediatric Rheumatology, National Referral Centre of Auto-Inflammatory Diseases and Inflammatory Amyloidosis, CEREMAIA, CHU de Bicêtre, APHP, University of Paris Saclay, Le Kremlin Bicêtre, France., Bader-Meunier B; Department of Pediatric Immunology, Hematology and Rheumatology, Necker Hospital, AP-HP, National Reference Centre for Rare Rheumatic and Autoimmune Systemic Diseases in Children, RAISE, France., Hassold N; Department of Pediatric Rheumatology, National Referral Centre of Auto-Inflammatory Diseases and Inflammatory Amyloidosis, CEREMAIA, CHU de Bicêtre, APHP, University of Paris Saclay, Le Kremlin Bicêtre, France., Comarmond C; Department of Internal Medicine and Clinical Immunology, Lariboisière Hospital, AP-HP, Paris, France., Lambert M; Univ. Lille, Inserm, CHU Lille, Department of Internal Medicine and Clinical Immunology, Hopital Claude Huriez, CERAINOM, U1286 - INFINITE - Institute for Translational Research in Inflammation, Lille, France., Mirault T; Université Paris Cité, National Reference Center for Rare Arterial diseases - CRMR MARS, FAVA-MULTI, VASCERN, Department of Vascular Medicine, Hôpital Européen Georges-Pompidou, AP-HP, Paris, France., Benhamou Y; Department of Internal Medicine, CHU de Rouen, UniRouen, Rouen, France., Espitia O; Nantes Université, CHU Nantes Department of Internal and Vascular Medicine, CNRS UMR 6291, INSERM UMR 1087, l'institut du Thorax Team III Vascular and Pulmonary Diseases, F-44000, Nantes, France., Redheuil A; Sorbonne Université, INSERM 1146, CNRS 7371, Laboratoire d'Imagerie Biomédicale, Department of Cardiovascular Radiology, Pitié-Salpêtrière Hospital AP-HP, Paris, France., Gaudric J; Department of Vascular and Endovascular Surgery-Tertiary Aortic Center, Pitié-Salpêtrière University Hospital, Assistance Publique-Hôpitaux de Paris and Sorbonne Médecine Universités, Paris, France., Chiche L; Department of Vascular and Endovascular Surgery-Tertiary Aortic Center, Pitié-Salpêtrière University Hospital, Assistance Publique-Hôpitaux de Paris and Sorbonne Médecine Universités, Paris, France., Cacoub P; Sorbonne Universités AP-HP, Groupe Hospitalier Pitié-Salpêtrière, Département de Médecine Interne et Immunologie Clinique, F-75013, Centre National de Référence Maladies Autoimmunes Systémiques Rares, Centre National de Référence Maladies Autoinflammatoires et Amylose Inflammatoire (CEREMAIA), Inflammation-Immunopathology-Biotherapy Department (DMU 3iD), CIC Biotherapy, INSERM 959, Groupe Hospitalier Pitié-Salpetriere, AP-HP, Paris, France., Kougkas N; Fourth Department of Internal Medicine, Hippokration Hospital, Aristotle University of Thessaloniki, Greece., Tombetti E; Department of Internal Medicine, ASST Fatebenefratelli-Sacco, Fatebenefratelli Hospital, 20121, Milan, Italy., Salvarani C; Division of Rheumatology, Azienda USL-IRCCS di Reggio Emilia and Università di Modena e Reggio Emilia, Reggio Emilia, Italy., Silva de Souza AW; Rheumatology Division, Department of Medicine, Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, SP, Brazil., Misra DP; Department of Clinical Immunology and Rheumatology, Sanjay Gandhi Postgraduate Institute of Medical Sciences (SGPGIMS), Lucknow, India., Chevret S; Biostatistics Department, Saint Louis Hospital, Assistance Publique-Hôpitaux de Paris, Université Paris-Cité, Paris, France., Saadoun D; Sorbonne Universités AP-HP, Groupe Hospitalier Pitié-Salpêtrière, Département de Médecine Interne et Immunologie Clinique, F-75013, Centre National de Référence Maladies Autoimmunes Systémiques Rares, Centre National de Référence Maladies Autoinflammatoires et Amylose Inflammatoire (CEREMAIA), Inflammation-Immunopathology-Biotherapy Department (DMU 3iD), CIC Biotherapy, INSERM 959, Groupe Hospitalier Pitié-Salpetriere, AP-HP, Paris, France. Electronic address: david.saadoun@aphp.fr.
Source: Journal of autoimmunity [J Autoimmun] 2026 May; Vol. 160, pp. 103550. Date of Electronic Publication: 2026 Apr 08.
Publication Type: Journal Article; Multicenter Study
Journal Info: Publisher: Academic Press Country of Publication: England NLM ID: 8812164 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1095-9157 (Electronic) Linking ISSN: 08968411 NLM ISO Abbreviation: J Autoimmun Subsets: MEDLINE
Database: MEDLINE Ultimate
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PubType: Academic Journal
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  Data: Takayasu arteritis phenotypes and outcomes: A data-driven cluster analysis from a large international cohort.
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  Data: <searchLink fieldCode="AU" term="%22Vieira+M%22">Vieira M</searchLink>; Sorbonne Universités AP-HP, Groupe Hospitalier Pitié-Salpêtrière, Département de Médecine Interne et Immunologie Clinique, F-75013, Centre National de Référence Maladies Autoimmunes Systémiques Rares, Centre National de Référence Maladies Autoinflammatoires et Amylose Inflammatoire (CEREMAIA), Inflammation-Immunopathology-Biotherapy Department (DMU 3iD), CIC Biotherapy, INSERM 959, Groupe Hospitalier Pitié-Salpetriere, AP-HP, Paris, France; Rheumatology Division, Department of Internal Medicine, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil.<br /><searchLink fieldCode="AU" term="%22Ghayad+E%22">Ghayad E</searchLink>; Sorbonne Universités AP-HP, Groupe Hospitalier Pitié-Salpêtrière, Département de Médecine Interne et Immunologie Clinique, F-75013, Centre National de Référence Maladies Autoimmunes Systémiques Rares, Centre National de Référence Maladies Autoinflammatoires et Amylose Inflammatoire (CEREMAIA), Inflammation-Immunopathology-Biotherapy Department (DMU 3iD), CIC Biotherapy, INSERM 959, Groupe Hospitalier Pitié-Salpetriere, AP-HP, Paris, France.<br /><searchLink fieldCode="AU" term="%22Aeschlimann+FA%22">Aeschlimann FA</searchLink>; Department of Rheumatology, University Children's Hospital Basel UKBB, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Peres+Lima+JP%22">Peres Lima JP</searchLink>; Rheumatology Division, Department of Medicine, Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, SP, Brazil.<br /><searchLink fieldCode="AU" term="%22Marvisi+C%22">Marvisi C</searchLink>; Division of Rheumatology, Azienda USL-IRCCS di Reggio Emilia and Università di Modena e Reggio Emilia, Reggio Emilia, Italy.<br /><searchLink fieldCode="AU" term="%22Iacomelli+G%22">Iacomelli G</searchLink>; Department of Internal Medicine, ASST Fatebenefratelli-Sacco, Fatebenefratelli Hospital, 20121, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Mekinian+A%22">Mekinian A</searchLink>; Department of Internal Medicine, Sorbonne Universités, AP-HP, Hôpital Saint-Antoine, Centre National de Référence Maladies Autoimmunes Systémiques Rares, Centre National de Référence Maladies Autoinflammatoires et Amylose Inflammatoire (CEREMAIA), Inflammation-Immunopathology-Biotherapy Department (DMU 3iD), Paris, France.<br /><searchLink fieldCode="AU" term="%22Koné-Paut+I%22">Koné-Paut I</searchLink>; Department of Pediatric Rheumatology, National Referral Centre of Auto-Inflammatory Diseases and Inflammatory Amyloidosis, CEREMAIA, CHU de Bicêtre, APHP, University of Paris Saclay, Le Kremlin Bicêtre, France.<br /><searchLink fieldCode="AU" term="%22Bader-Meunier+B%22">Bader-Meunier B</searchLink>; Department of Pediatric Immunology, Hematology and Rheumatology, Necker Hospital, AP-HP, National Reference Centre for Rare Rheumatic and Autoimmune Systemic Diseases in Children, RAISE, France.<br /><searchLink fieldCode="AU" term="%22Hassold+N%22">Hassold N</searchLink>; Department of Pediatric Rheumatology, National Referral Centre of Auto-Inflammatory Diseases and Inflammatory Amyloidosis, CEREMAIA, CHU de Bicêtre, APHP, University of Paris Saclay, Le Kremlin Bicêtre, France.<br /><searchLink fieldCode="AU" term="%22Comarmond+C%22">Comarmond C</searchLink>; Department of Internal Medicine and Clinical Immunology, Lariboisière Hospital, AP-HP, Paris, France.<br /><searchLink fieldCode="AU" term="%22Lambert+M%22">Lambert M</searchLink>; Univ. Lille, Inserm, CHU Lille, Department of Internal Medicine and Clinical Immunology, Hopital Claude Huriez, CERAINOM, U1286 - INFINITE - Institute for Translational Research in Inflammation, Lille, France.<br /><searchLink fieldCode="AU" term="%22Mirault+T%22">Mirault T</searchLink>; Université Paris Cité, National Reference Center for Rare Arterial diseases - CRMR MARS, FAVA-MULTI, VASCERN, Department of Vascular Medicine, Hôpital Européen Georges-Pompidou, AP-HP, Paris, France.<br /><searchLink fieldCode="AU" term="%22Benhamou+Y%22">Benhamou Y</searchLink>; Department of Internal Medicine, CHU de Rouen, UniRouen, Rouen, France.<br /><searchLink fieldCode="AU" term="%22Espitia+O%22">Espitia O</searchLink>; Nantes Université, CHU Nantes Department of Internal and Vascular Medicine, CNRS UMR 6291, INSERM UMR 1087, l'institut du Thorax Team III Vascular and Pulmonary Diseases, F-44000, Nantes, France.<br /><searchLink fieldCode="AU" term="%22Redheuil+A%22">Redheuil A</searchLink>; Sorbonne Université, INSERM 1146, CNRS 7371, Laboratoire d'Imagerie Biomédicale, Department of Cardiovascular Radiology, Pitié-Salpêtrière Hospital AP-HP, Paris, France.<br /><searchLink fieldCode="AU" term="%22Gaudric+J%22">Gaudric J</searchLink>; Department of Vascular and Endovascular Surgery-Tertiary Aortic Center, Pitié-Salpêtrière University Hospital, Assistance Publique-Hôpitaux de Paris and Sorbonne Médecine Universités, Paris, France.<br /><searchLink fieldCode="AU" term="%22Chiche+L%22">Chiche L</searchLink>; Department of Vascular and Endovascular Surgery-Tertiary Aortic Center, Pitié-Salpêtrière University Hospital, Assistance Publique-Hôpitaux de Paris and Sorbonne Médecine Universités, Paris, France.<br /><searchLink fieldCode="AU" term="%22Cacoub+P%22">Cacoub P</searchLink>; Sorbonne Universités AP-HP, Groupe Hospitalier Pitié-Salpêtrière, Département de Médecine Interne et Immunologie Clinique, F-75013, Centre National de Référence Maladies Autoimmunes Systémiques Rares, Centre National de Référence Maladies Autoinflammatoires et Amylose Inflammatoire (CEREMAIA), Inflammation-Immunopathology-Biotherapy Department (DMU 3iD), CIC Biotherapy, INSERM 959, Groupe Hospitalier Pitié-Salpetriere, AP-HP, Paris, France.<br /><searchLink fieldCode="AU" term="%22Kougkas+N%22">Kougkas N</searchLink>; Fourth Department of Internal Medicine, Hippokration Hospital, Aristotle University of Thessaloniki, Greece.<br /><searchLink fieldCode="AU" term="%22Tombetti+E%22">Tombetti E</searchLink>; Department of Internal Medicine, ASST Fatebenefratelli-Sacco, Fatebenefratelli Hospital, 20121, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Salvarani+C%22">Salvarani C</searchLink>; Division of Rheumatology, Azienda USL-IRCCS di Reggio Emilia and Università di Modena e Reggio Emilia, Reggio Emilia, Italy.<br /><searchLink fieldCode="AU" term="%22Silva+de+Souza+AW%22">Silva de Souza AW</searchLink>; Rheumatology Division, Department of Medicine, Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, SP, Brazil.<br /><searchLink fieldCode="AU" term="%22Misra+DP%22">Misra DP</searchLink>; Department of Clinical Immunology and Rheumatology, Sanjay Gandhi Postgraduate Institute of Medical Sciences (SGPGIMS), Lucknow, India.<br /><searchLink fieldCode="AU" term="%22Chevret+S%22">Chevret S</searchLink>; Biostatistics Department, Saint Louis Hospital, Assistance Publique-Hôpitaux de Paris, Université Paris-Cité, Paris, France.<br /><searchLink fieldCode="AU" term="%22Saadoun+D%22">Saadoun D</searchLink>; Sorbonne Universités AP-HP, Groupe Hospitalier Pitié-Salpêtrière, Département de Médecine Interne et Immunologie Clinique, F-75013, Centre National de Référence Maladies Autoimmunes Systémiques Rares, Centre National de Référence Maladies Autoinflammatoires et Amylose Inflammatoire (CEREMAIA), Inflammation-Immunopathology-Biotherapy Department (DMU 3iD), CIC Biotherapy, INSERM 959, Groupe Hospitalier Pitié-Salpetriere, AP-HP, Paris, France. Electronic address: david.saadoun@aphp.fr.
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  Data: <searchLink fieldCode="JN" term="%228812164%22">Journal of autoimmunity</searchLink> [J Autoimmun] 2026 May; Vol. 160, pp. 103550. <i>Date of Electronic Publication: </i>2026 Apr 08.
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