Meloaxilines A-E, five unprecedented monoterpenoid indole alkaloids from Melodinus axillaris, suppress colorectal cancer by targeting the iron metabolism pathway.
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| Title: | Meloaxilines A-E, five unprecedented monoterpenoid indole alkaloids from Melodinus axillaris, suppress colorectal cancer by targeting the iron metabolism pathway. |
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| Authors: | Du KC; Key Labzoratory of Ethnomedicine Material Basis & Pharmacological Mechanisms, Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang 110016, China; Joint International Research Laboratory of Intelligent Drug Delivery Systems of Ministry of Education, Shenyang Pharmaceutical University, Shenyang 110016, China., Li GC; Key Labzoratory of Ethnomedicine Material Basis & Pharmacological Mechanisms, Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang 110016, China; Joint International Research Laboratory of Intelligent Drug Delivery Systems of Ministry of Education, Shenyang Pharmaceutical University, Shenyang 110016, China., Li YH; Key Labzoratory of Ethnomedicine Material Basis & Pharmacological Mechanisms, Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang 110016, China; Joint International Research Laboratory of Intelligent Drug Delivery Systems of Ministry of Education, Shenyang Pharmaceutical University, Shenyang 110016, China., Xu XB; Key Labzoratory of Ethnomedicine Material Basis & Pharmacological Mechanisms, Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang 110016, China; Joint International Research Laboratory of Intelligent Drug Delivery Systems of Ministry of Education, Shenyang Pharmaceutical University, Shenyang 110016, China., Hua HM; Key Labzoratory of Ethnomedicine Material Basis & Pharmacological Mechanisms, Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang 110016, China., Kongkatitham V; Center of Excellence in Natural Products for Ageing and Chronic Diseases, Faculty of Pharmaceutical Sciences, Chulalongkorn University, Bangkok 10330, Thailand., Wang YM; Key Labzoratory of Ethnomedicine Material Basis & Pharmacological Mechanisms, Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang 110016, China; Joint International Research Laboratory of Intelligent Drug Delivery Systems of Ministry of Education, Shenyang Pharmaceutical University, Shenyang 110016, China. Electronic address: WYM9585@163.com., Rojsitthisak P; Department of Pharmaceutics, School of Pharmacy, Shenyang Pharmaceutical University, 103 Wenhua Road, Shenyang 110016, China; Center of Excellence in Natural Products for Ageing and Chronic Diseases, Faculty of Pharmaceutical Sciences, Chulalongkorn University, Bangkok 10330, Thailand. Electronic address: pornchai.r@chula.ac.th., Meng DL; Key Labzoratory of Ethnomedicine Material Basis & Pharmacological Mechanisms, Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang 110016, China; Joint International Research Laboratory of Intelligent Drug Delivery Systems of Ministry of Education, Shenyang Pharmaceutical University, Shenyang 110016, China. Electronic address: mengdl@163.com. |
| Source: | Bioorganic chemistry [Bioorg Chem] 2026 Jul 15; Vol. 176, pp. 109845. Date of Electronic Publication: 2026 Apr 08. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Elsevier Country of Publication: United States NLM ID: 1303703 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2120 (Electronic) Linking ISSN: 00452068 NLM ISO Abbreviation: Bioorg Chem Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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