Modulation of TNF-α, IL-1β and myeloperoxidase contributes to the anti-inflammatory and analgesic effects of Paullinia pinnata Linn (Sapindaceae) extracts in complete Freund's adjuvant-induced mono-arthritis in rats.

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Title: Modulation of TNF-α, IL-1β and myeloperoxidase contributes to the anti-inflammatory and analgesic effects of Paullinia pinnata Linn (Sapindaceae) extracts in complete Freund's adjuvant-induced mono-arthritis in rats.
Authors: Tseuguem PP; Research Unit of Animal Physiology and Phytopharmacology, Faculty of Sciences, University of Dschang, P.O. Box 67, Dschang, Cameroon; Laboratory of Applied Chemistry and Bioscience (LACB), Department of Chemistry and Biology, Faculty of Sciences, University of Bertoua, P.O. Box 416, Bertoua, Cameroon. Electronic address: piuspum@gmail.com., Kuete CF; Department of Neuroscience and Center for Advanced Pain Studies, The University of Texas at Dallas, 800 W. Campbell Road, Richardson, TX, 75080, USA. Electronic address: christian.kuetefofie@utdallas.edu., Tabatabaei SM; Department of Pharmaceutical Sciences, University of Kentucky, Lexington, KY 40536, USA. Electronic address: sahar.mofidi@uky.edu., Treat A; Department of Neuroscience and Center for Advanced Pain Studies, The University of Texas at Dallas, 800 W. Campbell Road, Richardson, TX, 75080, USA. Electronic address: annytreat@gmail.com., Kolber BJ; Department of Neuroscience and Center for Advanced Pain Studies, The University of Texas at Dallas, 800 W. Campbell Road, Richardson, TX, 75080, USA. Electronic address: benedict.kolber@utdallas.edu., Tidgewell KJ; Department of Pharmaceutical Sciences, University of Kentucky, Lexington, KY 40536, USA. Electronic address: kevin.tidgewell@uky.edu., Nguelefack TB; Research Unit of Animal Physiology and Phytopharmacology, Faculty of Sciences, University of Dschang, P.O. Box 67, Dschang, Cameroon. Electronic address: nguelefack@yahoo.fr.
Source: Journal of ethnopharmacology [J Ethnopharmacol] 2026 Jul 15; Vol. 366, pp. 121635. Date of Electronic Publication: 2026 Apr 07.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Sequoia Country of Publication: Ireland NLM ID: 7903310 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-7573 (Electronic) Linking ISSN: 03788741 NLM ISO Abbreviation: J Ethnopharmacol Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1872-7573
DOI:10.1016/j.jep.2026.121635