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Modulation of TNF-α, IL-1β and myeloperoxidase contributes to the anti-inflammatory and analgesic effects of Paullinia pinnata Linn (Sapindaceae) extracts in complete Freund's adjuvant-induced mono-arthritis in rats.

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Title: Modulation of TNF-α, IL-1β and myeloperoxidase contributes to the anti-inflammatory and analgesic effects of Paullinia pinnata Linn (Sapindaceae) extracts in complete Freund's adjuvant-induced mono-arthritis in rats.
Authors: Tseuguem PP; Research Unit of Animal Physiology and Phytopharmacology, Faculty of Sciences, University of Dschang, P.O. Box 67, Dschang, Cameroon; Laboratory of Applied Chemistry and Bioscience (LACB), Department of Chemistry and Biology, Faculty of Sciences, University of Bertoua, P.O. Box 416, Bertoua, Cameroon. Electronic address: piuspum@gmail.com., Kuete CF; Department of Neuroscience and Center for Advanced Pain Studies, The University of Texas at Dallas, 800 W. Campbell Road, Richardson, TX, 75080, USA. Electronic address: christian.kuetefofie@utdallas.edu., Tabatabaei SM; Department of Pharmaceutical Sciences, University of Kentucky, Lexington, KY 40536, USA. Electronic address: sahar.mofidi@uky.edu., Treat A; Department of Neuroscience and Center for Advanced Pain Studies, The University of Texas at Dallas, 800 W. Campbell Road, Richardson, TX, 75080, USA. Electronic address: annytreat@gmail.com., Kolber BJ; Department of Neuroscience and Center for Advanced Pain Studies, The University of Texas at Dallas, 800 W. Campbell Road, Richardson, TX, 75080, USA. Electronic address: benedict.kolber@utdallas.edu., Tidgewell KJ; Department of Pharmaceutical Sciences, University of Kentucky, Lexington, KY 40536, USA. Electronic address: kevin.tidgewell@uky.edu., Nguelefack TB; Research Unit of Animal Physiology and Phytopharmacology, Faculty of Sciences, University of Dschang, P.O. Box 67, Dschang, Cameroon. Electronic address: nguelefack@yahoo.fr.
Source: Journal of ethnopharmacology [J Ethnopharmacol] 2026 Jul 15; Vol. 366, pp. 121635. Date of Electronic Publication: 2026 Apr 07.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Sequoia Country of Publication: Ireland NLM ID: 7903310 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-7573 (Electronic) Linking ISSN: 03788741 NLM ISO Abbreviation: J Ethnopharmacol Subsets: MEDLINE
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  Data: Modulation of TNF-α, IL-1β and myeloperoxidase contributes to the anti-inflammatory and analgesic effects of Paullinia pinnata Linn (Sapindaceae) extracts in complete Freund's adjuvant-induced mono-arthritis in rats.
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  Data: <searchLink fieldCode="AU" term="%22Tseuguem+PP%22">Tseuguem PP</searchLink>; Research Unit of Animal Physiology and Phytopharmacology, Faculty of Sciences, University of Dschang, P.O. Box 67, Dschang, Cameroon; Laboratory of Applied Chemistry and Bioscience (LACB), Department of Chemistry and Biology, Faculty of Sciences, University of Bertoua, P.O. Box 416, Bertoua, Cameroon. Electronic address: piuspum@gmail.com.<br /><searchLink fieldCode="AU" term="%22Kuete+CF%22">Kuete CF</searchLink>; Department of Neuroscience and Center for Advanced Pain Studies, The University of Texas at Dallas, 800 W. Campbell Road, Richardson, TX, 75080, USA. Electronic address: christian.kuetefofie@utdallas.edu.<br /><searchLink fieldCode="AU" term="%22Tabatabaei+SM%22">Tabatabaei SM</searchLink>; Department of Pharmaceutical Sciences, University of Kentucky, Lexington, KY 40536, USA. Electronic address: sahar.mofidi@uky.edu.<br /><searchLink fieldCode="AU" term="%22Treat+A%22">Treat A</searchLink>; Department of Neuroscience and Center for Advanced Pain Studies, The University of Texas at Dallas, 800 W. Campbell Road, Richardson, TX, 75080, USA. Electronic address: annytreat@gmail.com.<br /><searchLink fieldCode="AU" term="%22Kolber+BJ%22">Kolber BJ</searchLink>; Department of Neuroscience and Center for Advanced Pain Studies, The University of Texas at Dallas, 800 W. Campbell Road, Richardson, TX, 75080, USA. Electronic address: benedict.kolber@utdallas.edu.<br /><searchLink fieldCode="AU" term="%22Tidgewell+KJ%22">Tidgewell KJ</searchLink>; Department of Pharmaceutical Sciences, University of Kentucky, Lexington, KY 40536, USA. Electronic address: kevin.tidgewell@uky.edu.<br /><searchLink fieldCode="AU" term="%22Nguelefack+TB%22">Nguelefack TB</searchLink>; Research Unit of Animal Physiology and Phytopharmacology, Faculty of Sciences, University of Dschang, P.O. Box 67, Dschang, Cameroon. Electronic address: nguelefack@yahoo.fr.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier+Sequoia%22">Elsevier Sequoia </searchLink><i>Country of Publication: </i>Ireland <i>NLM ID: </i>7903310 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1872-7573 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2203788741%22">03788741 </searchLink><i>NLM ISO Abbreviation: </i>J Ethnopharmacol <i>Subsets: </i>MEDLINE
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