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Mode of action guided metagenomic natural product discovery reveals convergent evolution of a ClpP-targeting motif.

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Title: Mode of action guided metagenomic natural product discovery reveals convergent evolution of a ClpP-targeting motif.
Authors: Kan J; Laboratory of Genetically Encoded Small Molecules, The Rockefeller University, New York, NY, USA., Spotton K; Laboratory of Genetically Encoded Small Molecules, The Rockefeller University, New York, NY, USA.; Tri-Institutional PhD Program in Chemical Biology, The Rockefeller University, New York, NY, USA., Morales-Amador A; Laboratory of Genetically Encoded Small Molecules, The Rockefeller University, New York, NY, USA., Hernandez Y; Laboratory of Genetically Encoded Small Molecules, The Rockefeller University, New York, NY, USA., Burian J; Laboratory of Genetically Encoded Small Molecules, The Rockefeller University, New York, NY, USA., Panfil C; Laboratory of Genetically Encoded Small Molecules, The Rockefeller University, New York, NY, USA., Ternei MA; Laboratory of Genetically Encoded Small Molecules, The Rockefeller University, New York, NY, USA., Boer RE; Laboratory of Genetically Encoded Small Molecules, The Rockefeller University, New York, NY, USA., Bhattacharjee A; Laboratory of Genetically Encoded Small Molecules, The Rockefeller University, New York, NY, USA., Brady SF; Laboratory of Genetically Encoded Small Molecules, The Rockefeller University, New York, NY, USA. sbrady@rockefeller.edu.
Source: Nature communications [Nat Commun] 2026 Apr 09; Vol. 17 (1). Date of Electronic Publication: 2026 Apr 09.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Mode of action guided metagenomic natural product discovery reveals convergent evolution of a ClpP-targeting motif.
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  Data: <searchLink fieldCode="AU" term="%22Kan+J%22">Kan J</searchLink>; Laboratory of Genetically Encoded Small Molecules, The Rockefeller University, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Spotton+K%22">Spotton K</searchLink>; Laboratory of Genetically Encoded Small Molecules, The Rockefeller University, New York, NY, USA.; Tri-Institutional PhD Program in Chemical Biology, The Rockefeller University, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Morales-Amador+A%22">Morales-Amador A</searchLink>; Laboratory of Genetically Encoded Small Molecules, The Rockefeller University, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Hernandez+Y%22">Hernandez Y</searchLink>; Laboratory of Genetically Encoded Small Molecules, The Rockefeller University, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Burian+J%22">Burian J</searchLink>; Laboratory of Genetically Encoded Small Molecules, The Rockefeller University, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Panfil+C%22">Panfil C</searchLink>; Laboratory of Genetically Encoded Small Molecules, The Rockefeller University, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Ternei+MA%22">Ternei MA</searchLink>; Laboratory of Genetically Encoded Small Molecules, The Rockefeller University, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Boer+RE%22">Boer RE</searchLink>; Laboratory of Genetically Encoded Small Molecules, The Rockefeller University, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Bhattacharjee+A%22">Bhattacharjee A</searchLink>; Laboratory of Genetically Encoded Small Molecules, The Rockefeller University, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Brady+SF%22">Brady SF</searchLink>; Laboratory of Genetically Encoded Small Molecules, The Rockefeller University, New York, NY, USA. sbrady@rockefeller.edu.
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  Data: <searchLink fieldCode="JN" term="%22101528555%22">Nature communications</searchLink> [Nat Commun] 2026 Apr 09; Vol. 17 (1). <i>Date of Electronic Publication: </i>2026 Apr 09.
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              Text: 2026 Apr 09
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