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SMODA: Interpretable Multimodal Omics Integration for Disease Classification and Subtype Discovery via Heterogeneous Transfer Learning.

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Title: SMODA: Interpretable Multimodal Omics Integration for Disease Classification and Subtype Discovery via Heterogeneous Transfer Learning.
Authors: Zhao J; Metabolomics Subcenter of the National Genomics Data Center, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian 116023, China.; University of Chinese Academy of Sciences, Beijing 100049, China.; Liaoning Province Key Laboratory of Metabolomics, Dalian 116023, China., Bao H; Metabolomics Subcenter of the National Genomics Data Center, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian 116023, China.; University of Chinese Academy of Sciences, Beijing 100049, China.; Liaoning Province Key Laboratory of Metabolomics, Dalian 116023, China., Guan P; Metabolomics Subcenter of the National Genomics Data Center, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian 116023, China.; University of Chinese Academy of Sciences, Beijing 100049, China.; Liaoning Province Key Laboratory of Metabolomics, Dalian 116023, China., Zhao X; Metabolomics Subcenter of the National Genomics Data Center, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian 116023, China.; University of Chinese Academy of Sciences, Beijing 100049, China.; Liaoning Province Key Laboratory of Metabolomics, Dalian 116023, China., Wang B; Metabolomics Subcenter of the National Genomics Data Center, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian 116023, China.; University of Chinese Academy of Sciences, Beijing 100049, China.; Liaoning Province Key Laboratory of Metabolomics, Dalian 116023, China., Yan Z; Metabolomics Subcenter of the National Genomics Data Center, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian 116023, China.; Liaoning Province Key Laboratory of Metabolomics, Dalian 116023, China.; School of Chemistry, Dalian University of Technology, Dalian 116024, China., Zhao C; Metabolomics Subcenter of the National Genomics Data Center, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian 116023, China.; University of Chinese Academy of Sciences, Beijing 100049, China.; Liaoning Province Key Laboratory of Metabolomics, Dalian 116023, China., Zhao Y; Metabolomics Subcenter of the National Genomics Data Center, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian 116023, China.; Liaoning Province Key Laboratory of Metabolomics, Dalian 116023, China., Lu X; Metabolomics Subcenter of the National Genomics Data Center, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian 116023, China.; University of Chinese Academy of Sciences, Beijing 100049, China.; Liaoning Province Key Laboratory of Metabolomics, Dalian 116023, China., Xu G; Metabolomics Subcenter of the National Genomics Data Center, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian 116023, China.; University of Chinese Academy of Sciences, Beijing 100049, China.; Liaoning Province Key Laboratory of Metabolomics, Dalian 116023, China.
Source: Analytical chemistry [Anal Chem] 2026 Apr 21; Vol. 98 (15), pp. 10997-11009. Date of Electronic Publication: 2026 Apr 10.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 0370536 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-6882 (Electronic) Linking ISSN: 00032700 NLM ISO Abbreviation: Anal Chem Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: SMODA: Interpretable Multimodal Omics Integration for Disease Classification and Subtype Discovery via Heterogeneous Transfer Learning.
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  Data: <searchLink fieldCode="AU" term="%22Zhao+J%22">Zhao J</searchLink>; Metabolomics Subcenter of the National Genomics Data Center, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian 116023, China.; University of Chinese Academy of Sciences, Beijing 100049, China.; Liaoning Province Key Laboratory of Metabolomics, Dalian 116023, China.<br /><searchLink fieldCode="AU" term="%22Bao+H%22">Bao H</searchLink>; Metabolomics Subcenter of the National Genomics Data Center, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian 116023, China.; University of Chinese Academy of Sciences, Beijing 100049, China.; Liaoning Province Key Laboratory of Metabolomics, Dalian 116023, China.<br /><searchLink fieldCode="AU" term="%22Guan+P%22">Guan P</searchLink>; Metabolomics Subcenter of the National Genomics Data Center, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian 116023, China.; University of Chinese Academy of Sciences, Beijing 100049, China.; Liaoning Province Key Laboratory of Metabolomics, Dalian 116023, China.<br /><searchLink fieldCode="AU" term="%22Zhao+X%22">Zhao X</searchLink>; Metabolomics Subcenter of the National Genomics Data Center, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian 116023, China.; University of Chinese Academy of Sciences, Beijing 100049, China.; Liaoning Province Key Laboratory of Metabolomics, Dalian 116023, China.<br /><searchLink fieldCode="AU" term="%22Wang+B%22">Wang B</searchLink>; Metabolomics Subcenter of the National Genomics Data Center, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian 116023, China.; University of Chinese Academy of Sciences, Beijing 100049, China.; Liaoning Province Key Laboratory of Metabolomics, Dalian 116023, China.<br /><searchLink fieldCode="AU" term="%22Yan+Z%22">Yan Z</searchLink>; Metabolomics Subcenter of the National Genomics Data Center, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian 116023, China.; Liaoning Province Key Laboratory of Metabolomics, Dalian 116023, China.; School of Chemistry, Dalian University of Technology, Dalian 116024, China.<br /><searchLink fieldCode="AU" term="%22Zhao+C%22">Zhao C</searchLink>; Metabolomics Subcenter of the National Genomics Data Center, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian 116023, China.; University of Chinese Academy of Sciences, Beijing 100049, China.; Liaoning Province Key Laboratory of Metabolomics, Dalian 116023, China.<br /><searchLink fieldCode="AU" term="%22Zhao+Y%22">Zhao Y</searchLink>; Metabolomics Subcenter of the National Genomics Data Center, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian 116023, China.; Liaoning Province Key Laboratory of Metabolomics, Dalian 116023, China.<br /><searchLink fieldCode="AU" term="%22Lu+X%22">Lu X</searchLink>; Metabolomics Subcenter of the National Genomics Data Center, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian 116023, China.; University of Chinese Academy of Sciences, Beijing 100049, China.; Liaoning Province Key Laboratory of Metabolomics, Dalian 116023, China.<br /><searchLink fieldCode="AU" term="%22Xu+G%22">Xu G</searchLink>; Metabolomics Subcenter of the National Genomics Data Center, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian 116023, China.; University of Chinese Academy of Sciences, Beijing 100049, China.; Liaoning Province Key Laboratory of Metabolomics, Dalian 116023, China.
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  Data: <searchLink fieldCode="JN" term="%220370536%22">Analytical chemistry</searchLink> [Anal Chem] 2026 Apr 21; Vol. 98 (15), pp. 10997-11009. <i>Date of Electronic Publication: </i>2026 Apr 10.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Chemical+Society%22">American Chemical Society </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>0370536 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1520-6882 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200032700%22">00032700 </searchLink><i>NLM ISO Abbreviation: </i>Anal Chem <i>Subsets: </i>MEDLINE
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      – Type: doi
        Value: 10.1021/acs.analchem.5c06539
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      – Code: eng
        Text: English
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        StartPage: 10997
    Titles:
      – TitleFull: SMODA: Interpretable Multimodal Omics Integration for Disease Classification and Subtype Discovery via Heterogeneous Transfer Learning.
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            NameFull: Zhao J
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            NameFull: Bao H
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            – D: 21
              M: 04
              Text: 2026 Apr 21
              Type: published
              Y: 2026
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              Value: 98
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            – TitleFull: Analytical chemistry
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