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Cultured ex vivo human brain tissue maintains cell-type transcriptional identities.

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Title: Cultured ex vivo human brain tissue maintains cell-type transcriptional identities.
Authors: McGinnis JP; Department of Neurosurgery, Baylor College of Medicine, Houston, TX 77030, USA.; Jan and Dan Duncan Neurological Research Institute, Texas Children's Hospital, Houston, TX 77030, USA., Mallannagari S; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA.; Jan and Dan Duncan Neurological Research Institute, Texas Children's Hospital, Houston, TX 77030, USA., Guevara MC; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA.; Jan and Dan Duncan Neurological Research Institute, Texas Children's Hospital, Houston, TX 77030, USA., Ortiz-Guzman J; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA.; Jan and Dan Duncan Neurological Research Institute, Texas Children's Hospital, Houston, TX 77030, USA., Belfort BDW; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA.; Jan and Dan Duncan Neurological Research Institute, Texas Children's Hospital, Houston, TX 77030, USA.; Medical Scientist Training Program, Baylor College of Medicine, Houston, TX 77030, USA., Bao S; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA.; Development, Disease Models & Therapeutics Graduate Program, Baylor College of Medicine, Houston, TX 77030, USA., Srivastava S; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA.; Jan and Dan Duncan Neurological Research Institute, Texas Children's Hospital, Houston, TX 77030, USA.; Medical Scientist Training Program, Baylor College of Medicine, Houston, TX 77030, USA., Morkas M; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA., Ji E; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA., Katlowitz KA; Department of Neurosurgery, Baylor College of Medicine, Houston, TX 77030, USA., Addison A; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA.; Development, Disease Models & Therapeutics Graduate Program, Baylor College of Medicine, Houston, TX 77030, USA., Tantry EK; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA.; Jan and Dan Duncan Neurological Research Institute, Texas Children's Hospital, Houston, TX 77030, USA., Mohila CA; Department of Pathology, Texas Children's Hospital, Baylor College of Medicine, Houston, TX 77030, USA., Blessing MM; Department of Pathology, Texas Children's Hospital, Baylor College of Medicine, Houston, TX 77030, USA., Gadgil N; Department of Neurosurgery, Baylor College of Medicine, Houston, TX 77030, USA.; Department of Neurosurgery, Texas Children's Hospital, Baylor College of Medicine, Houston, TX 77030, USA., McClugage SG 3rd; Department of Neurosurgery, Baylor College of Medicine, Houston, TX 77030, USA.; Department of Neurosurgery, Texas Children's Hospital, Baylor College of Medicine, Houston, TX 77030, USA., Bauer DF; Department of Neurosurgery, Baylor College of Medicine, Houston, TX 77030, USA.; Department of Neurosurgery, Texas Children's Hospital, Baylor College of Medicine, Houston, TX 77030, USA., Whitehead WE; Department of Neurosurgery, Baylor College of Medicine, Houston, TX 77030, USA.; Department of Neurosurgery, Texas Children's Hospital, Baylor College of Medicine, Houston, TX 77030, USA., Aldave G; Department of Neurosurgery, Baylor College of Medicine, Houston, TX 77030, USA.; Department of Neurosurgery, Texas Children's Hospital, Baylor College of Medicine, Houston, TX 77030, USA., Tanweer O; Department of Neurosurgery, Baylor College of Medicine, Houston, TX 77030, USA., Jaleel N; Department of Neurosurgery, Baylor College of Medicine, Houston, TX 77030, USA., Jalali A; Department of Neurosurgery, Baylor College of Medicine, Houston, TX 77030, USA., Patel AJ; Department of Neurosurgery, Baylor College of Medicine, Houston, TX 77030, USA., Sheth SA; Department of Neurosurgery, Baylor College of Medicine, Houston, TX 77030, USA., Weiner HL; Department of Neurosurgery, Baylor College of Medicine, Houston, TX 77030, USA.; Department of Neurosurgery, Texas Children's Hospital, Baylor College of Medicine, Houston, TX 77030, USA., Gopinath S; Department of Neurosurgery, Baylor College of Medicine, Houston, TX 77030, USA., Rao G; Department of Neurosurgery, Baylor College of Medicine, Houston, TX 77030, USA., Harmanci AS; Department of Neurosurgery, Baylor College of Medicine, Houston, TX 77030, USA.; Jan and Dan Duncan Neurological Research Institute, Texas Children's Hospital, Houston, TX 77030, USA., Curry D; Department of Neurosurgery, Baylor College of Medicine, Houston, TX 77030, USA.; Department of Neurosurgery, Texas Children's Hospital, Baylor College of Medicine, Houston, TX 77030, USA., Arenkiel BR; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA.; Jan and Dan Duncan Neurological Research Institute, Texas Children's Hospital, Houston, TX 77030, USA.
Source: Brain communications [Brain Commun] 2026 Mar 09; Vol. 8 (2), pp. fcag073. Date of Electronic Publication: 2026 Mar 09 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 101755125 Publication Model: eCollection Cited Medium: Internet ISSN: 2632-1297 (Electronic) Linking ISSN: 26321297 NLM ISO Abbreviation: Brain Commun Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Cultured ex vivo human brain tissue maintains cell-type transcriptional identities.
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  Data: <searchLink fieldCode="AU" term="%22McGinnis+JP%22">McGinnis JP</searchLink>; Department of Neurosurgery, Baylor College of Medicine, Houston, TX 77030, USA.; Jan and Dan Duncan Neurological Research Institute, Texas Children's Hospital, Houston, TX 77030, USA.<br /><searchLink fieldCode="AU" term="%22Mallannagari+S%22">Mallannagari S</searchLink>; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA.; Jan and Dan Duncan Neurological Research Institute, Texas Children's Hospital, Houston, TX 77030, USA.<br /><searchLink fieldCode="AU" term="%22Guevara+MC%22">Guevara MC</searchLink>; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA.; Jan and Dan Duncan Neurological Research Institute, Texas Children's Hospital, Houston, TX 77030, USA.<br /><searchLink fieldCode="AU" term="%22Ortiz-Guzman+J%22">Ortiz-Guzman J</searchLink>; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA.; Jan and Dan Duncan Neurological Research Institute, Texas Children's Hospital, Houston, TX 77030, USA.<br /><searchLink fieldCode="AU" term="%22Belfort+BDW%22">Belfort BDW</searchLink>; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA.; Jan and Dan Duncan Neurological Research Institute, Texas Children's Hospital, Houston, TX 77030, USA.; Medical Scientist Training Program, Baylor College of Medicine, Houston, TX 77030, USA.<br /><searchLink fieldCode="AU" term="%22Bao+S%22">Bao S</searchLink>; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA.; Development, Disease Models & Therapeutics Graduate Program, Baylor College of Medicine, Houston, TX 77030, USA.<br /><searchLink fieldCode="AU" term="%22Srivastava+S%22">Srivastava S</searchLink>; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA.; Jan and Dan Duncan Neurological Research Institute, Texas Children's Hospital, Houston, TX 77030, USA.; 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Department of Neurosurgery, Baylor College of Medicine, Houston, TX 77030, USA.<br /><searchLink fieldCode="AU" term="%22Patel+AJ%22">Patel AJ</searchLink>; Department of Neurosurgery, Baylor College of Medicine, Houston, TX 77030, USA.<br /><searchLink fieldCode="AU" term="%22Sheth+SA%22">Sheth SA</searchLink>; Department of Neurosurgery, Baylor College of Medicine, Houston, TX 77030, USA.<br /><searchLink fieldCode="AU" term="%22Weiner+HL%22">Weiner HL</searchLink>; Department of Neurosurgery, Baylor College of Medicine, Houston, TX 77030, USA.; Department of Neurosurgery, Texas Children's Hospital, Baylor College of Medicine, Houston, TX 77030, USA.<br /><searchLink fieldCode="AU" term="%22Gopinath+S%22">Gopinath S</searchLink>; Department of Neurosurgery, Baylor College of Medicine, Houston, TX 77030, USA.<br /><searchLink fieldCode="AU" term="%22Rao+G%22">Rao G</searchLink>; Department of Neurosurgery, Baylor College of Medicine, Houston, TX 77030, USA.<br /><searchLink fieldCode="AU" term="%22Harmanci+AS%22">Harmanci AS</searchLink>; 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  Data: <searchLink fieldCode="JN" term="%22101755125%22">Brain communications</searchLink> [Brain Commun] 2026 Mar 09; Vol. 8 (2), pp. fcag073. <i>Date of Electronic Publication: </i>2026 Mar 09 (<i>Print Publication: </i>2026).
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Oxford+University+Press%22">Oxford University Press </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101755125 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Internet <i>ISSN: </i>2632-1297 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2226321297%22">26321297 </searchLink><i>NLM ISO Abbreviation: </i>Brain Commun <i>Subsets: </i>PubMed not MEDLINE
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