Evaluation of the Prevalence of Occult Fibrin in Donor Organs, Its Origins, and Consequences: Insights From the COPE Studies.

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Title: Evaluation of the Prevalence of Occult Fibrin in Donor Organs, Its Origins, and Consequences: Insights From the COPE Studies.
Authors: Watson CJE; Department of Surgery, Addenbrookes Hospital, University of Cambridge, Cambridge, United Kingdom.; The Roy Calne Transplant Unit, Cambridge University Hospitals NHS Foundation Trust, Cambridge, United Kingdom.; National Institute for Health and Care Research, Cambridge Biomedical Research Centre, Cambridge, United Kingdom.; National Institute for Health and Care Research Blood and Transplant Research Unit in Organ Donation and Transplantation, at The University of Cambridge, in Collaboration With Newcastle University, in Partnership With National Health Service Blood and Transplant (NHSBT), Cambridge, United Kingdom., Jochmans I; Laboratory of Abdominal Transplantation, Transplantation Research Group, Department of Microbiology, Immunology and Transplantation, KU Leuven, and Abdominal Transplant Surgery, University Hospitals Leuven, Leuven, Belgium., Macdonald S; Specialist Haemostasis Laboratory, Cambridge University Hospitals NHS Foundation Trust, Cambridge, United Kingdom., White D; Specialist Haemostasis Laboratory, Cambridge University Hospitals NHS Foundation Trust, Cambridge, United Kingdom., Bridgeman C; Specialist Haemostasis Laboratory, Cambridge University Hospitals NHS Foundation Trust, Cambridge, United Kingdom., Butler AJ; Department of Surgery, Addenbrookes Hospital, University of Cambridge, Cambridge, United Kingdom.; The Roy Calne Transplant Unit, Cambridge University Hospitals NHS Foundation Trust, Cambridge, United Kingdom.; National Institute for Health and Care Research, Cambridge Biomedical Research Centre, Cambridge, United Kingdom.; National Institute for Health and Care Research Blood and Transplant Research Unit in Organ Donation and Transplantation, at The University of Cambridge, in Collaboration With Newcastle University, in Partnership With National Health Service Blood and Transplant (NHSBT), Cambridge, United Kingdom., Gaurav R; The Roy Calne Transplant Unit, Cambridge University Hospitals NHS Foundation Trust, Cambridge, United Kingdom.; National Institute for Health and Care Research, Cambridge Biomedical Research Centre, Cambridge, United Kingdom.; National Institute for Health and Care Research Blood and Transplant Research Unit in Organ Donation and Transplantation, at The University of Cambridge, in Collaboration With Newcastle University, in Partnership With National Health Service Blood and Transplant (NHSBT), Cambridge, United Kingdom., Swift L; The Roy Calne Transplant Unit, Cambridge University Hospitals NHS Foundation Trust, Cambridge, United Kingdom., Paterson AL; National Institute for Health and Care Research, Cambridge Biomedical Research Centre, Cambridge, United Kingdom.; Department of Histopathology, Cambridge University Hospitals NHS Foundation Trust, Cambridge, United Kingdom., Lo Faro L; Oxford Transplant Research Group, Nuffield Department of Surgical Sciences, John Radcliffe Hospital, University of Oxford, Oxford, United Kingdom., Kaisar ME; Oxford Transplant Research Group, Nuffield Department of Surgical Sciences, John Radcliffe Hospital, University of Oxford, Oxford, United Kingdom., Nasralla D; Liver Transplant Unit, The Royal Free London NHS Foundation Trust, London, United Kingdom., Husen P; Department of General, Visceral and Transplant Surgery, University Hospital Heidelberg, Heidelberg, Germany., Cross S; Nuffield Department of Surgical Sciences, University of Oxford, and The Oxford Biomedical Research Centre, Oxford, United Kingdom., Friend PJ; Oxford Transplant Research Group, Nuffield Department of Surgical Sciences, John Radcliffe Hospital, University of Oxford, Oxford, United Kingdom.; Nuffield Department of Surgical Sciences, University of Oxford, and The Oxford Biomedical Research Centre, Oxford, United Kingdom., Ploeg RJ; Oxford Transplant Research Group, Nuffield Department of Surgical Sciences, John Radcliffe Hospital, University of Oxford, Oxford, United Kingdom.; Nuffield Department of Surgical Sciences, University of Oxford, and The Oxford Biomedical Research Centre, Oxford, United Kingdom., Kosmoliaptsis V; Department of Surgery, Addenbrookes Hospital, University of Cambridge, Cambridge, United Kingdom.; The Roy Calne Transplant Unit, Cambridge University Hospitals NHS Foundation Trust, Cambridge, United Kingdom.; National Institute for Health and Care Research, Cambridge Biomedical Research Centre, Cambridge, United Kingdom.; National Institute for Health and Care Research Blood and Transplant Research Unit in Organ Donation and Transplantation, at The University of Cambridge, in Collaboration With Newcastle University, in Partnership With National Health Service Blood and Transplant (NHSBT), Cambridge, United Kingdom.
Source: Transplant international : official journal of the European Society for Organ Transplantation [Transpl Int] 2026 Mar 25; Vol. 39, pp. 15547. Date of Electronic Publication: 2026 Mar 25 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Media S. A Country of Publication: Switzerland NLM ID: 8908516 Publication Model: eCollection Cited Medium: Internet ISSN: 1432-2277 (Electronic) Linking ISSN: 09340874 NLM ISO Abbreviation: Transpl Int Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Watson+CJE%22">Watson CJE</searchLink>; Department of Surgery, Addenbrookes Hospital, University of Cambridge, Cambridge, United Kingdom.; The Roy Calne Transplant Unit, Cambridge University Hospitals NHS Foundation Trust, Cambridge, United Kingdom.; National Institute for Health and Care Research, Cambridge Biomedical Research Centre, Cambridge, United Kingdom.; National Institute for Health and Care Research Blood and Transplant Research Unit in Organ Donation and Transplantation, at The University of Cambridge, in Collaboration With Newcastle University, in Partnership With National Health Service Blood and Transplant (NHSBT), Cambridge, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Jochmans+I%22">Jochmans I</searchLink>; Laboratory of Abdominal Transplantation, Transplantation Research Group, Department of Microbiology, Immunology and Transplantation, KU Leuven, and Abdominal Transplant Surgery, University Hospitals Leuven, Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Macdonald+S%22">Macdonald S</searchLink>; Specialist Haemostasis Laboratory, Cambridge University Hospitals NHS Foundation Trust, Cambridge, United Kingdom.<br /><searchLink fieldCode="AU" term="%22White+D%22">White D</searchLink>; Specialist Haemostasis Laboratory, Cambridge University Hospitals NHS Foundation Trust, Cambridge, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Bridgeman+C%22">Bridgeman C</searchLink>; Specialist Haemostasis Laboratory, Cambridge University Hospitals NHS Foundation Trust, Cambridge, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Butler+AJ%22">Butler AJ</searchLink>; Department of Surgery, Addenbrookes Hospital, University of Cambridge, Cambridge, United Kingdom.; The Roy Calne Transplant Unit, Cambridge University Hospitals NHS Foundation Trust, Cambridge, United Kingdom.; National Institute for Health and Care Research, Cambridge Biomedical Research Centre, Cambridge, United Kingdom.; National Institute for Health and Care Research Blood and Transplant Research Unit in Organ Donation and Transplantation, at The University of Cambridge, in Collaboration With Newcastle University, in Partnership With National Health Service Blood and Transplant (NHSBT), Cambridge, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Gaurav+R%22">Gaurav R</searchLink>; 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Oxford Transplant Research Group, Nuffield Department of Surgical Sciences, John Radcliffe Hospital, University of Oxford, Oxford, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Kaisar+ME%22">Kaisar ME</searchLink>; Oxford Transplant Research Group, Nuffield Department of Surgical Sciences, John Radcliffe Hospital, University of Oxford, Oxford, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Nasralla+D%22">Nasralla D</searchLink>; Liver Transplant Unit, The Royal Free London NHS Foundation Trust, London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Husen+P%22">Husen P</searchLink>; Department of General, Visceral and Transplant Surgery, University Hospital Heidelberg, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Cross+S%22">Cross S</searchLink>; Nuffield Department of Surgical Sciences, University of Oxford, and The Oxford Biomedical Research Centre, Oxford, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Friend+PJ%22">Friend PJ</searchLink>; Oxford Transplant Research Group, Nuffield Department of Surgical Sciences, John Radcliffe Hospital, University of Oxford, Oxford, United Kingdom.; Nuffield Department of Surgical Sciences, University of Oxford, and The Oxford Biomedical Research Centre, Oxford, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Ploeg+RJ%22">Ploeg RJ</searchLink>; Oxford Transplant Research Group, Nuffield Department of Surgical Sciences, John Radcliffe Hospital, University of Oxford, Oxford, United Kingdom.; Nuffield Department of Surgical Sciences, University of Oxford, and The Oxford Biomedical Research Centre, Oxford, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Kosmoliaptsis+V%22">Kosmoliaptsis V</searchLink>; Department of Surgery, Addenbrookes Hospital, University of Cambridge, Cambridge, United Kingdom.; The Roy Calne Transplant Unit, Cambridge University Hospitals NHS Foundation Trust, Cambridge, United Kingdom.; National Institute for Health and Care Research, Cambridge Biomedical Research Centre, Cambridge, United Kingdom.; National Institute for Health and Care Research Blood and Transplant Research Unit in Organ Donation and Transplantation, at The University of Cambridge, in Collaboration With Newcastle University, in Partnership With National Health Service Blood and Transplant (NHSBT), Cambridge, United Kingdom.
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